Fc EPSILON R1 ALPHA, Antibody

GenWay ID: GWB-140C55
Legacy ID: 20-783-74199
Size: 0.1 mg
Source: Mouse
Reactivity: Human
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Details for Fc EPSILON R1 ALPHA, Antibody

Specificity: Fc EPSILON R1 ALPHA

NCBI Gene ID: 2205

Isotype: IgG2b

Specificity: Fc EPSILON R1 ALPHA

Clone: 9E1

Appox. Protein Concentration: Lot specific and is stated on the vial

Synonyms: FCE1A Fusion Partner: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0-Ag14 myeloma cell line. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Buffer Solution: Phosphate buffered saline

Preservative Stabilisers: 0.09% Sodium Azide

Suggested Dilution: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul
Suggested Dilution: Flow Cytometry - 1/50 - 1/100 Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface.

Subunit: IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A.

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Similarity: Belongs to the CD3Z/FCER1G family.

Similarity: Contains 1 ITAM domain. 1. Vangelista. L. et al. (2002) A minimal receptor-Ig chimera of human Fc epsilon R1 alpha-chain efficiently binds secretory and membrane IgE. Protein Engineering. 15: 51-57.2. Vangelista. L. et al. (2002) Efficient folding of the Fc epsilonR1 alpha-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1.

Additional Info for Fc EPSILON R1 ALPHA, Antibody

Name Fc EPSILON R1 ALPHA, Antibody
Related Product Names MOUSE ANTI HUMAN FC EPSILON R1 ALPHA Fc EPSILON R1 ALPHAFCER1G
NCBI Acc Number NP_004097.1
Format Purified
Stability 18 months from date of despatch.
Clonality Monoclonal
Storage Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a pr
Molecular Weight 9667
Swiss Prot Number P12319
Applications ELISA, FACS/FC, IF, IP, WB

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