GenWay ID: GWB-140C55
Legacy ID: 20-783-74199
Size: 0.1 mg
Source: Mouse
Reactivity: Human
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Details for Fc EPSILON R1 ALPHA, Antibody

Specificity: Fc EPSILON R1 ALPHA

NCBI Gene ID: 2205

Isotype: IgG2b

Specificity: Fc EPSILON R1 ALPHA

Clone: 9E1

Appox. Protein Concentration: Lot specific and is stated on the vial

Synonyms: FCE1A Fusion Partner: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0-Ag14 myeloma cell line. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Buffer Solution: Phosphate buffered saline

Preservative Stabilisers: 0.09% Sodium Azide

Suggested Dilution: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul
Suggested Dilution: Flow Cytometry - 1/50 - 1/100 Function: Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface.

Subunit: IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A.

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Similarity: Belongs to the CD3Z/FCER1G family.

Similarity: Contains 1 ITAM domain. 1. Vangelista. L. et al. (2002) A minimal receptor-Ig chimera of human Fc epsilon R1 alpha-chain efficiently binds secretory and membrane IgE. Protein Engineering. 15: 51-57.2. Vangelista. L. et al. (2002) Efficient folding of the Fc epsilonR1 alpha-chain membrane-proximal domain D2 depends on the presence of the N-terminal domain D1.

Additional Info for Fc EPSILON R1 ALPHA, Antibody

Name Fc EPSILON R1 ALPHA, Antibody
NCBI Acc Number NP_004097.1
Format Purified
Stability 18 months from date of despatch.
Clonality Monoclonal
Storage Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a pr
Molecular Weight 9667
Swiss Prot Number P12319
Applications ELISA, FACS/FC, IF, IP, WB

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