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Recombinant Proteins
GenWay has a diverse recombinant protein expression platform that combines the technologies of bioinformatics, protein domain analysis, gene codon optimization, protein fusion, and protein expression in different host cells. The multi-functional platform for recombinant protein production depicted in Figure 1 allows GenWay to produce soluble and functional proteins. In particular, GenWay has the capability and vector systems for expression of difficult proteins such as proteases, kinases, glycosylated and membrane proteins. We have a very high success rate (almost 100%) and can deliver the proteins in a timely fashion. This is a core competency necessary for efficient and effective production of immunogens and affinity ligands for antibody production and purification. 
Figure 1. GenWay’s protein production platform.
To meet the demands of producing recombinant proteins in a soluble and/or functional form, multiple expression systems that employ different host cells are designed and constructed to form a multi-functional expression platform. Recombinant proteins can be produced through the 3-tiered platform depicted above according to the requirements of the end product and other factors such as solubility, post-translational modifications, functionality, timeline, and cost consideration. The platform is designed to overcome difficulties of protein expression in a particular host cell system and enhance the success rate of production.
Our vector system contains plasmid vectors and recombinant viral vectors. GenWay's adenoviral (Ad) vectors can be used for expressing proteins at high levels in mammalian cell lines. The protein production process starts with the gene ID or GenBank Accession number. Our staff will determine your particular needs for the final product, and will design specifications to meet your needs. We offer a customized service package and competitive prices for recombinant protein expression. Please click the following URLs for more detailed information about our custom protein expression services and recombinant protein products  
 

General Protein Expression Services Literature
Protein Expression Poster
E. coli System
Insect Cell System
Yeast-Pichia expression 
Mammalian Cell System 

 

Proteins SuperMix Case Study Highly-Abundant Proteins 12 Protein Expression
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