Anti- Kalirin (isoform 2) Antibody

GenWay ID: GWB-B423AA
Legacy ID: 18-202-335512
Size: 0.1 mg
Source: Goat
Reactivity: Mouse
Expected from sequence similarity: Human, Mouse, Rat
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Details for Anti- Kalirin (isoform 2) Antibody

Related Products: 06-202-339484 - Immunizing Peptide

Sequence: Peptide with sequence C-RWHLGPGDPFSTYV, from the C Terminus of the Notes: Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Approx 200kDa band observed in Mouse Brain lysates (calculated MW of 192kDa according to XP_001001845). Recommended concentration: 1-3ug/ml.

Immunogen: The protein sequence Summary: Huntington\'s disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This protein is a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]. [1] Ma,X.M., Wang,Y., Ferraro,F., Mains,R.E. and Eipper,B.A., et al.
Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons
[2] Youn,H., Jeoung,M., Koo,Y., Ji,H., Markesbery,W.R., Ji,I. and Ji,T.H.
Kalirin is under-expressed in Alzheimer\'s disease hippocampus
[3] Wang,L., Hauser,E.R., Shah,S.H., Pericak-Vance,M.A., Haynes,C., Crosslin,D., Harris,M., Nelson,S., Hale,A.B., Granger,C.B.,, et al.
Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease
[4] Koo,T.H., Eipper,B.A. and Donaldson,J.G., et al.
Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation
[5] Beausoleil,S.A., Villen,J., Gerber,S.A., Rush,J. and Gygi,S.P., et al.
A probability-based approach for high-throughput protein phosphorylation analysis and site localization

Additional Info for Anti- Kalirin (isoform 2) Antibody

Name Anti- Kalirin (isoform 2) Antibody
Related Product Names DUET; DUO; HAPIP; TRADKalirin (isoform 2)KALRN
NCBI Acc Number NP_003938.1
GI Number 4504335
Purity Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Clonality Polyclonal
Storage Aliquot and store at -20°C
Sequence Length 1663
Applications E, WB

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