Anti- MICA (MHC class I polypeptide-related sequence A) Antibody

GenWay ID: GWB-864CC7
Legacy ID: 18-003-44554
Size: 0.1 mg
Source: Rabbit
Reactivity: Human
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Details for Anti- MICA (MHC class I polypeptide-related sequence A) Antibody

Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human MICA. ELISA Titre: 1:312500 Category: Signaling Intermediates

Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. MICA is expressed on the cell surface. although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamm

Summary: MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.

Summary: MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. [provided by RefSeq]. Boissel.N.. (2006) J. Immunol. 176 (8). 5108-5116.

Additional Info for Anti- MICA (MHC class I polypeptide-related sequence A) Antibody

Name Anti- MICA (MHC class I polypeptide-related sequence A) Antibody
Related Product Names MICA (MHC class I polypeptide-related sequence A)MICA
NCBI Acc Number NP_000238.1
GI Number 4557751
Purity Rabbit IgG purified by protein A chromatography.
Format Suggested dilution at 2.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Stability Note: Avoid repeat freeze-thaw cycles.
Clonality Polyclonal
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Molecular Weight 42 kDa
Sequence Length 383
Applications WB

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