SSTR4 antibody, Somatostatin receptor type 4 Antibody, Rabbit Polyclonal Antibody

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Somatostatin receptor type 4 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-461-10096

Buy SSTR4 antibody -

Volume:

Related Product Names:

- SSTR4 antibody; SSTR4; Somatostatin receptor type 4
- SS4R; Somatostatin receptor 4

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: SSTR4	Gene Name Synonym: N/A
Gi #: 4557863	NCBI Acc #: NP_001043.1	Swiss Prot Acc #: P31391
Length (aa): 388	Mol. Weight (Da): 41895	Chrom Location: 20p11.2

Immunogen: N-terminal extracellular domain of human. Synthetic peptide - KLH conjugated.

Uses: IHC (3 - 6 ug/ml) (Optimal dilution to be determined by the researcher)

Source/Host: Rabbit

Purity/Purification: Immunoaffinity Purified

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Storage: -4 degree C for short term (weeks) and -70 degree C for long term.

Stability: 6-12 months at -20 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for SSTR4 ANTIBODY:

IHC: Tested

ELISA, ICC, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Pancreas, Islet of Langerhans ( anti-SSTR4 )

SSTR4 antibody IHC image
SSTR4

SSTR4 ANTIBODY TARGET DESCRIPTION:

Synonym Names for SSTR4 antibody: SSTR4; SS4R; Somatostatin receptor 4

Function: Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.

Subcellular Location: Membrane; multi-pass membrane protein.

Tissue Specificity: Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.

Similarity: Belongs to the G-protein coupled receptor 1 family [view classification].

Summary: Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung.

Somatostatin receptor type 4 reacts with human.

OMIM: 182454; gene. [NCBI / EBI]

Products similar to SSTR4 antibody:

IgG

SSTR4 (somatostatin receptor 4), IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for SSTR4 ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Pasquali,D., Notaro,A., Bonavolonta',G., Vassallo,P., Bellastella,A. and Sinisi,A.A.
     Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease
[2] Hansson,J., Bjartell,A., Gadaleanu,V., Dizeyi,N. and Abrahamsson,P.A.
     Expression of somatostatin receptor subtypes 2 and 4 in human benign prostatic hyperplasia and prostatic cancer
[3] Papotti,M., Bongiovanni,M., Volante,M., Allia,E., Landolfi,S., Helboe,L., Schindler,M., Cole,S.L. and Bussolati,G.
     Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis
[4] Pasquali,D., Notaro,A., Esposito,D., Vassallo,P., Bonavolonta,G., Bellastella,A. and Sinisi,A.A.
     [Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy]
[5] Talme,T., Ivanoff,J., Hagglund,M., Van Neerven,R.J., Ivanoff,A. and Sundqvist,K.G.
     Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3
[6] , Xu Y., Song J., Bruno J.F., Berelowitz M.
     Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4.
[7] , Rohrer L., Raulf F., Bruns C., Buettner R., Hofstaedter F., Schuele R.
     Cloning and characterization of a fourth human somatostatin receptor.
[8] , Yamada Y., Kagimoto S., Kubota A., Yasuda K., Masuda K., Someya Y., Ihara Y., Li Q., Imura H., Seino S., et al.
     Cloning, functional expression and pharmacological characterization of a fourth (hSSTR4) and a fifth (hSSTR5) human somatostatin receptor subtype.
[9] , Demchyshyn L.L., Srikant C.B., Sunahara R.K., Kent G., Seeman P., van Tol H.H.M., Panetta R., Patel Y.C., Niznik H.B.
     Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20.
[10] , Kopatz S.A., Aronstam R.S., Sharma S.V.
     cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org).

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: SSTR4 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of SSTR4 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about SSTR4 antibody, all related information, articles, resources about SSTR4 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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