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| P2Y purinoceptor 11 Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-461-10113 |
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| Related Product Names:
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P2RY11 antibody; P2RY11; P2Y11; P2Y purinoceptor 11
- P2Y11; Purinergic receptor P2Y11 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: P2RY11 |
Gene Name Synonym: P2Y11 |
Gi #:
23463303 |
NCBI Acc #:
NP_002557.2 |
Swiss Prot Acc #:
Q96G91 |
Length (aa): 374 |
Mol. Weight (Da): 40345 |
Chrom Location: 19p13.2 |
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 Immunogen: 3rd extracellular domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (8 - 16 ug/ml) (Optimal dilution to be determined by the researcher)
Source/Host: Rabbit
Purity/Purification: Immunoaffinity Purified
Clonality: Polyclonal
Crossreactivity: Human
Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.
Storage: -4 degree C for short term (weeks) and -70 degree C for long term.
Stability: 6-12 months at -20 degree C.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for P2RY11 ANTIBODY: |
| IHC: Tested |
| ELISA, ICC, Western Blot: Not Tested |
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| P2RY11 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for P2RY11 antibody: P2RY11; P2Y11; P2Y11; Purinergic receptor P2Y11
Function: Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.
Subcellular Location: Membrane; multi-pass membrane protein.
Tissue Specificity: Highest expression in the spleen, lower in the small intestine.
Induction: Increased by DMSO and retinoic acid.
Miscellaneous: A putative trans-splicing which involves PPAN and P2RY11 gene regions produces a fusion protein.
Similarity: Belongs to the G-protein coupled receptor 1 family [view classification].
Summary: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.
P2Y purinoceptor 11 reacts with human.
OMIM: 602697; gene. [NCBI / EBI]
Products similar to P2RY11 antibody:
IgG
 P2Y purinoceptor 11, IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for P2RY11 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
[1] Duhant,X., Schandene,L., Bruyns,C., Gonzalez,N.S., Goldman,M., Boeynaems,J.M. and Communi,D.
Extracellular adenine nucleotides inhibit the activation of human CD4+ T lymphocytes
[2] Moore,D.J., Chambers,J.K., Wahlin,J.P., Tan,K.B., Moore,G.B., Jenkins,O., Emson,P.C. and Murdock,P.R.
Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study
[3] Communi,D., Suarez-Huerta,N., Dussossoy,D., Savi,P. and Boeynaems,J.M.
Cotranscription and intergenic splicing of human P2Y11 and SSF1 genes
[4] van der Weyden,L., Conigrave,A.D. and Morris,M.B., et al.
Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor
[5] Communi,D., Govaerts,C., Parmentier,M. and Boeynaems,J.M., et al.
Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase
[6] , Communi D.
Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
[7] , King M.M., Aronstam R.S., Sharma S.V.
Isolation of cDNA coding for purinergic receptor P2Y, G protein-coupled, 11 (P2RY11).
[8] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[9] , Communi D., Govaerts C., Parmentier M., Boeynaems J.-M.
Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase.
[10] , Communi D., Suarez-Huerta N., Dussossoy D., Savi P., Boeynaems J.-M.
Cotranscription and intergenic splicing of human P2Y11 and SSF1 genes. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: P2RY11 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of P2RY11 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about P2RY11 antibody, all related information, articles, resources about P2RY11 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. This product has been manufactured by MBL International. |
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