hGB1A antibody, Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant Antibody, Rabbit Polyclonal Antibody

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Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-461-10572

Buy hGB1A antibody -

Volume:

Related Product Names:

- hGB1A antibody; hGB1A; hGB1a; GPRC3A; GABABR1; GABBR1-3; GABAB(1e); dJ271M21.1.1; dJ271M21.1.2; Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant
- Gamma-aminobutyric acid (GABA) B receptor 1 isoform a

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: hGB1A	Gene Name Synonym: hGB1a; GPRC3A; GABABR1; GABBR1-3; GABAB(1e); dJ271M21.1.1; dJ271M21.1.2
Gi #: 10835015	NCBI Acc #: NP_001461.1	Swiss Prot Acc #: Q53EM0
Length (aa): 961	Mol. Weight (Da): 95134	Chrom Location: 6p21.31

Immunogen: N-terminal extracellular domain of human protein, near amino acid #200. Synthetic peptide - KLH conjugated.

Uses: IHC (9 - 18 ug/ml) (Optimal dilution to be determined by the researcher)

Source/Host: Rabbit

Purity/Purification: Immunoaffinity Purified

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Storage: -4 degree C for short term (weeks) and -70 degree C for long term.

Stability: 6-12 months at -20 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for HGB1A ANTIBODY:

IHC: Tested

ELISA, ICC, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Brain, Purkinje neurons ( anti-hGB1A )

hGB1A antibody IHC image
hGB1A

HGB1A ANTIBODY TARGET DESCRIPTION:

Synonym Names for hGB1A antibody: hGB1A; hGB1a; GPRC3A; GABABR1; GABBR1-3; GABAB(1e); dJ271M21.1.1; dJ271M21.1.2; Gamma-aminobutyric acid (GABA) B receptor 1 isoform a

Summary: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.

Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant reacts with human.

OMIM: NCBI [603540]

Pathways:
KEGG pathway: Neuroactive ligand-receptor interaction 04080

Products similar to hGB1A antibody:

IgG

Gamma-aminobutyric acid (GABA) B receptor 1 isoform b variant, IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for HGB1A ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Brock,C., Boudier,L., Maurel,D., Blahos,J. and Pin,J.P., et al.
     Assembly-dependent surface targeting of the heterodimeric GABAB Receptor is controlled by COPI but not 14-3-3
[2] Goudet,C., Kniazeff,J., Hlavackova,V., Malhaire,F., Maurel,D., Acher,F., Blahos,J., Prezeau,L. and Pin,J.P.
     Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators
[3] Iwakiri,M., Mizukami,K., Ikonomovic,M.D., Ishikawa,M., Hidaka,S., Abrahamson,E.E., DeKosky,S.T. and Asada,T.
     Changes in hippocampal GABABR1 subunit expression in Alzheimer's patients: association with Braak staging
[4] Zai,G., Arnold,P., Burroughs,E., Barr,C.L., Richter,M.A. and Kennedy,J.L.
     Evidence for the gamma-amino-butyric acid type B receptor 1 (GABBR1) gene as a susceptibility factor in obsessive-compulsive disorder
[5] Ma,S., Abou-Khalil,B., Sutcliffe,J.S., Haines,J.L. and Hedera,P., et al.
     The GABBR1 locus and the G1465A variant is not associated with temporal lobe epilepsy preceded by febrile seizures
[6] , Maruyama K., Sugano S.
     Oligo-capping : a simple method to replace the cap structure of eucaryotic mRNAs with oligoribonucleotides.
[7] , Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S.
     Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
[8] , Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
     Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: hGB1A antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of hGB1A antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about hGB1A antibody, all related information, articles, resources about hGB1A antibody are being stored on our online database. Let us know if you have questions regarding this product.

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