ADAMTS5 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 5, preproprotein Antibody, Rabbit Polyclonal Antibody

Alphabetical Listing of Primary Antibodies:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Alphabetical Listing of Proteins:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Peptides \| Secondary Antibodies \| ELISA Kits

ADAM metallopeptidase with thrombospondin type 1 motif, 5, preproprotein Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-461-10612

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Related Product Names:

- ADAMTS5 antibody; ADAMTS5; ADMP-2; ADAMTS11; FLJ36738; ADAM metallopeptidase with thrombospondin type 1 motif, 5, preproprotein
- ADAM metallopeptidase with thrombospondin type 1 motif, 5 preproprotein

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ADAMTS5	Gene Name Synonym: ADMP-2; ADAMTS11; FLJ36738
Gi #: 5901888	NCBI Acc #: NP_008969.1	Swiss Prot Acc #: Q52LV4
Length (aa): 930	Mol. Weight (Da): 101716	Chrom Location: 21q21.3

Immunogen: C-terminal domain of human. Synthetic peptide - KLH conjugated.

Uses: IHC (2 - 4 ug/ml) (Optimal dilution to be determined by the researcher)

Source/Host: Rabbit

Purity/Purification: Immunoaffinity Purified

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Storage: -4 degree C for short term (weeks) and -70 degree C for long term.

Stability: 6-12 months at -20 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ADAMTS5 ANTIBODY:

IHC: Tested

ELISA, ICC, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Cartilage ( anti-ADAMTS5 )

ADAMTS5 antibody IHC image
ADAMTS5

ADAMTS5 ANTIBODY TARGET DESCRIPTION:

Synonym Names for ADAMTS5 antibody: ADAMTS5; ADMP-2; ADAMTS11; FLJ36738; ADAM metallopeptidase with thrombospondin type 1 motif, 5 preproprotein

Summary: This protein is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

ADAM metallopeptidase with thrombospondin type 1 motif, 5, preproprotein reacts with human.

OMIM: NCBI [605007]

Products similar to ADAMTS5 antibody:

IgG

ADAMTS5, IgG

Rabbit anti ADAMTS-5 N-terminal, IgG

ADAM metallopeptidase with thrombospondin type 1 motif, 5, preproprotein, IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for ADAMTS5 ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Zeng,W., Corcoran,C., Collins-Racie,L.A., Lavallie,E.R., Morris,E.A. and Flannery,C.R.
     Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18
[2] Held-Feindt,J., Paredes,E.B., Blomer,U., Seidenbecher,C., Stark,A.M., Mehdorn,H.M. and Mentlein,R.
     Matrix-degrading proteases ADAMTS4 and ADAMTS5 (disintegrins and metalloproteinases with thrombospondin motifs 4 and 5) are expressed in human glioblastomas
[3] Cross,N.A., Chandrasekharan,S., Jokonya,N., Fowles,A., Hamdy,F.C., Buttle,D.J. and Eaton,C.L.
     The expression and regulation of ADAMTS-1, -4, -5, -9, and -15, and TIMP-3 by TGFbeta1 in prostate cells: relevance to the accumulation of versican
[4] Tortorella,M.D., Arner,E.C., Hills,R., Easton,A., Korte-Sarfaty,J., Fok,K., Wittwer,A.J., Liu,R.Q. and Malfait,A.M.
     Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes
[5] Tortorella,M.D., Liu,R.Q., Burn,T., Newton,R.C. and Arner,E., et al.
     Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)
[6] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

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Precautions: ADAMTS5 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ADAMTS5 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ADAMTS5 antibody, all related information, articles, resources about ADAMTS5 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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