MRGPRD antibody, Mas-related G-protein coupled receptor member D Antibody, Rabbit Polyclonal Antibody

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Mas-related G-protein coupled receptor member D Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-461-10765

Buy MRGPRD antibody -

Volume:

Related Product Names:

- MRGPRD antibody; MRGPRD; MRGD; Mas-related G-protein coupled receptor member D
- Beta-alanine receptor; G-protein coupled receptor TGR7; MAS-related GPR, member D

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: MRGPRD	Gene Name Synonym: MRGD
Gi #: 42794265	NCBI Acc #: NP_944605.2	Swiss Prot Acc #: Q8TDS7
Length (aa): 321	Mol. Weight (Da): 36118	Chrom Location: 11q13.2

Immunogen: 3rd cytoplasmic domain of human. Synthetic peptide - KLH conjugated.

Uses: IHC (17 ug/ml) (Optimal dilution to be determined by the researcher)

Source/Host: Rabbit

Purity/Purification: Immunoaffinity Purified

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Storage: -4 degree C for short term (weeks) and -70 degree C for long term.

Stability: 6-12 months at -20 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for MRGPRD ANTIBODY:

IHC: Tested

ELISA, ICC, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

Not Available

MRGPRD ANTIBODY TARGET DESCRIPTION:

Synonym Names for MRGPRD antibody: MRGPRD; MRGD; Beta-alanine receptor; G-protein coupled receptor TGR7; MAS-related GPR, member D

Function: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Subcellular Location: Cell membrane; multi-pass membrane protein. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily [view classification].

Mas-related G-protein coupled receptor member D reacts with human.

OMIM: 607231; gene. [NCBI / EBI]

Products similar to MRGPRD antibody:

IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for MRGPRD ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Shinohara,T., Harada,M., Ogi,K., Maruyama,M., Fujii,R., Tanaka,H., Fukusumi,S., Komatsu,H., Hosoya,M., Noguchi,Y., Watanabe,T.,, et al.
     Identification of a G protein-coupled receptor specifically responsive to beta-alanine
[2] Zylka,M.J., Dong,X., Southwell,A.L. and Anderson,D.J., et al.
     Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family
[3] Dong,X., Han,S., Zylka,M.J., Simon,M.I. and Anderson,D.J., et al.
     A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons
[4] , Zylka M.J., Dong X., Southwell A.L., Anderson D.J.
     Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.
[5] , Shinohara T., Harada M., Ogi K., Maruyama M., Fujii R., Tanaka H., Fukusumi S., Komatsu H., Hosoya M., Noguchi Y., et al.
     Identification of a G protein-coupled receptor specifically responsive to beta-alanine.
[6] , Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.
     Identification of G protein-coupled receptor genes from the human genome sequence.
[7] , Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y., et al.
     Genome-wide discovery and analysis of human seven transmembrane helix receptor genes.

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Precautions: MRGPRD antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of MRGPRD antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about MRGPRD antibody, all related information, articles, resources about MRGPRD antibody are being stored on our online database. Let us know if you have questions regarding this product.

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