GPCR antibody, Putative G-protein coupled receptor Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Putative G-protein coupled receptor Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-461-10778

Buy GPCR antibody -

Volume:

Related Product Names:

- GPCR antibody; GPCR; EVR1; FEVR; Fz-4; FzE4; GPCR; FZD4S; MGC34390; Putative G-protein coupled receptor
- Frizzled 4

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: GPCR	Gene Name Synonym: EVR1; FEVR; Fz-4; FzE4; GPCR; FZD4S; MGC34390
Gi #: 22547161	NCBI Acc #: NP_036325.2	Swiss Prot Acc #: Q8TDT8
Length (aa): 537	Mol. Weight (Da): 48661	Chrom Location: 11q14.2

Immunogen: N-terminal extracellular domain of human. Synthetic peptide - KLH conjugated.

Target Protein: Frizzled-4 (FZD4)

Uses: IHC (30 ug/ml) (Optimal dilution to be determined by the researcher)

Source/Host: Rabbit

Purity/Purification: Immunoaffinity Purified

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Storage: -4 degree C for short term (weeks) and -70 degree C for long term.

Stability: 6-12 months at -20 degree C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for GPCR ANTIBODY:

IHC: Tested

ELISA, ICC, Western Blot: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Kidney ( anti-GPCR )

GPCR antibody IHC image
GPCR

GPCR ANTIBODY TARGET DESCRIPTION:

Synonym Names for GPCR antibody: GPCR; EVR1; FEVR; Fz-4; FzE4; GPCR; FZD4S; MGC34390; Frizzled 4

Summary: This protein is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Putative G-protein coupled receptor reacts with human.

OMIM: NCBI [604579]

Pathways:
KEGG pathway: Colorectal cancer 05210
KEGG pathway: Wnt signaling pathway 04310

Products similar to GPCR antibody:

IgG

Histamine H3 receptor, IgG

HRH3, IgG

G-protein coupled receptor family C group 6 member A, IgG

Histamine receptor H4, IgG

G-protein coupled bile acid receptor 1, IgG

Protein

HISTAMINE RECEPTOR 3, Protein

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for GPCR ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Yoshida,S., Arita,R., Yoshida,A., Tada,H., Emori,A., Noda,Y., Nakao,S., Fujisawa,K. and Ishibashi,T.
     Novel mutation in FZD4 gene in a Japanese pedigree with familial exudative vitreoretinopathy
[2] Toomes,C., Bottomley,H.M., Scott,S., Mackey,D.A., Craig,J.E., Appukuttan,B., Stout,J.T., Flaxel,C.J., Zhang,K., Black,G.C.,, et al.
     Spectrum and frequency of FZD4 mutations in familial exudative vitreoretinopathy
[3] Omoto,S., Hayashi,T., Kitahara,K., Takeuchi,T. and Ueoka,Y., et al.
     Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R)
[4] Toomes,C., Bottomley,H.M., Jackson,R.M., Towns,K.V., Scott,S., Mackey,D.A., Craig,J.E., Jiang,L., Yang,Z., Trembath,R.,, et al.
     Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q
[5] Toomes,C., Downey,L.M., Bottomley,H.M., Scott,S., Woodruff,G., Trembath,R.C. and Inglehearn,C.F.
     Identification of a fourth locus (EVR4) for familial exudative vitreoretinopathy (FEVR)
[6] , Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.
     Identification of G protein-coupled receptor genes from the human genome sequence.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: GPCR antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of GPCR antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GPCR antibody, all related information, articles, resources about GPCR antibody are being stored on our online database. Let us know if you have questions regarding this product.

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