ARC antibody, Activity-regulated cytoskeleton-associated protein Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Activity-regulated cytoskeleton-associated protein Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-661-15047

Buy ARC antibody -

Size:

Related Product Names:

- ARC antibody; ARC; Activity-regulated cytoskeleton-associated protein
- ARC; ARC

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ARC	Gene Name Synonym: N/A
Gi #: 4505419	NCBI Acc #: NP_003937	Swiss Prot Acc #: Q7LC44
Length (aa): 208	Mol. Weight (Da): 22498	Chrom Location: N/A

Linear Protein Map with Immunogenic Epitope Marked (sequence source from above GI#)

Source/Host: Rabbit

Purity/Purification: It is supplied as immunoaffinity chromatography purified IgG.

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate-Buffered Saline, containing 0.02% sodium azide.

Storage: 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.

Stability: Store at -4 degree C for one year.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ARC ANTIBODY:

IHC, WB: Tested

ELISA, ICC: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Immunohistochemistry of ARC in human heart tissue (A) and skeletal muscle (B) with Anti-ARC (CT) at 5 ug/ml. ( anti-ARC )

ARC antibody IHC image
ARC

Western Blot: Western blot analysis of ARC in HeLa (H), KB (K), and A549 (A) whole cell lysates with anti-ARC (CT) at 1:1000 dilution. ( anti-ARC )

ARC antibody Western Blot image
ARC

ARC ANTIBODY TARGET DESCRIPTION:

Synonym Names for ARC antibody: ARC; ARC; ARC

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and –8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

Activity-regulated cytoskeleton-associated protein reacts with human.

Products similar to ARC antibody:

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SMARCA2, IgG

Peptide

MARCKS (Phospho-Ser158) Antibody Blocking Peptide, Peptide

MIP-4 Human, Protein

RNA polymerase transcriptional regulation mediator, subunit 6 homolog, Protein

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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for ARC ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Haug,K., Kremerskothen,J., Hallmann,K., Sander,T., Dullinger,J., Rau,B., Beyenburg,S., Lentze,M.J., Barnekow,A., Elger,C.E.,, et al.
     Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy
[2] Kremerskothen,J., Wendholt,D., Liedtke,T. and Barnekow,A., et al.
     cDNA Cloning, Genomic Organization, and Chromosomal Assignment of human 'Activity-Regulated Cytoskeleton-Associated Gene' (ARC)
[3] Kremerskothen,J., Wendholt,D., Liedtke,T. and Barnekow,A., et al.
     Direct Submission
[4] , Haug K., Kremerskothen J., Hallmann K., Sander T., Dullinger J., Rau B., Beyenburg S., Lentze M.J., Barnekow A., Elger C.E., et al.
     Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.
[5] , Kremerskothen J., Barnekow A.
     Human activity-regulated cytoskeleton-associated gene (ARC) maps to chromosome 8q24.
[6] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[7] , Strausberg R.
     Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ARC antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ARC antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ARC antibody, all related information, articles, resources about ARC antibody are being stored on our online database. Let us know if you have questions regarding this product.

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