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Alphabetical Listing of Proteins:
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Peptides
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Secondary Antibodies
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ELISA Kits
Baculoviral IAP repeat-containing protein 2 Antibody, Rabbit Polyclonal Antibody
Catalog Number: 18-661-15190
Buy BIRC2 antibody -
Size:
0.1 mg ($300.00)
0.5 mg ($1,050.00)
1 mg ($1,560.00)
Related Product Names:
- BIRC2 antibody; BIRC2; API1; IAP2; MIHB; HIAP2; RNF48; Baculoviral IAP repeat-containing protein 2
- Inhibitor of apoptosis protein 2; HIAP2; HIAP-2; C-IAP1; TNFR2-TRAF signaling complex protein 2; IAP homolog B; Baculoviral IAP repeat-containing protein 2
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
BIRC2
Gene Name Synonym:
API1; IAP2; MIHB; HIAP2; RNF48
Gi #:
4502141
NCBI Acc #:
NP_001157.1
Swiss Prot Acc #:
Q13490
Length (aa):
618
Mol. Weight (Da):
69900
Chrom Location:
11q22
Immunogen:
Raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1. This antibody detects bo
Source/Host:
Rabbit
Purity/Purification:
It is supplied as immunoaffinity purified IgG.
Clonality:
Polyclonal
Crossreactivity:
Human
Format:
Phosphate-Buffered Saline, containing 0.02% sodium azide.
Storage:
4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.
Stability:
Store at -4 degree C for one year.
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for BIRC2 ANTIBODY:
WB: Tested
ELISA, ICC, IHC: Not Tested
TESTING: (
secondary reagents
and
protocols
)
Western Blot:
Western blot analysis of c-IAP in human lung lysate with anti-c-IAP (CT) at 1 (lane A), 2 (lane B), and 4 (lane C) ug/ml, respectively. ( anti-BIRC2 )
BIRC2 antibody Western Blot image
BIRC2 ANTIBODY TARGET DESCRIPTION:
Synonym Names for BIRC2 antibody:
BIRC2; API1; IAP2; MIHB; HIAP2; RNF48; Inhibitor of apoptosis protein 2; HIAP2; HIAP-2; C-IAP1; TNFR2-TRAF signaling complex protein 2; IAP homolog B; Baculoviral IAP repeat-containing protein 2
Function:
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Subunit:
Interacts with SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity.
Subcellular Location:
Cytoplasm (Potential).
Tissue Specificity:
Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Similarity:
Belongs to the IAP family.
Similarity:
Contains 3 BIR repeats.
Similarity:
Contains 1 CARD domain.
Similarity:
Contains 1 RING-type zinc finger.
Summary:
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
Baculoviral IAP repeat-containing protein 2 reacts with human.
OMIM:
601712; gene. [
NCBI
/
EBI
]
Pathways:
KEGG pathway:
Apoptosis
04210
KEGG pathway:
Focal adhesion
04510
Products similar to BIRC2 antibody:
IgG
cIAP2, IgG
cIAP1, IgG
PRODUCT INTERACTIONS:
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-3, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-3, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3 active, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3 [3F48], IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3 [3F49], IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3 [T46L], IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit A' Hu Caspase 3, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASP3 (caspase 3. apoptosis-related cysteine peptidase), IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3 protease, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 3, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase-7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase-7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 7 [B4-G2], IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit anti Human Caspase 7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit anti Caspase 7 (CT), IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit anti Caspase 7 (NT), IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 7, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 7 active, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
CASPASE-9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9 [1-2], IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9 active, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit A' Caspase 9 (I20)(Intermed. Domain2), IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit A' Caspase 9 (I16)Intermed. Domain 1, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Rabbit anti Human Caspase 9, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9 active, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Caspase 9 (ready-to-use), IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Diablo homolog, mitochondrial, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Diablo homolog, mitochondrial, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
SMAC/DIABLO, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Mouse Anti-Human SMAC/DIABLO, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Anti-Smac/DIABLO, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Diablo, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Diablo, IgG
(GenWay Catalog #: 18-661-15190)
.
Baculoviral IAP repeat-containing protein 2
interacts
with
Diablo, IgG
(GenWay Catalog #: 18-661-15190)
.
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
BACKGROUND REFERENCES for BIRC2 ANTIBODY:
Background references for antibody target are not specific to GenWay products
[1]
Chang,Y.F., Cheng,C.M., Chang,L.K., Jong,Y.J. and Yuo,C.Y., et al.
The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination
[2]
Eckelman,B.P. and Salvesen,G.S., et al.
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
[3]
Samuel,T., Welsh,K., Lober,T., Togo,S.H., Zapata,J.M. and Reed,J.C., et al.
Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases
[4]
Peng,H., Huang,Y., Duan,Z., Erdmann,N., Xu,D., Herek,S. and Zheng,J.
Cellular IAP1 regulates TRAIL-induced apoptosis in human fetal cortical neural progenitor cells
[5]
Endo,K., Kohnoe,S., Tsujita,E., Watanabe,A., Nakashima,H., Baba,H. and Maehara,Y.
Modulation of anti-apoptosis by endogenous IAP expression in MKN45 human gastric cancer cells
[6]
, Rothe M., Pan M.-G., Henzel W.J., Ayres T.M., Goeddel D.V.
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.
[7]
, Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., Farahani R., McLean M., Ikeda J., Mackenzie A., et al.
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.
[8]
, Uren A.G., Pakusch M., Hawkins C.J., Puls K.L., Vaux D.L.
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
[9]
, Livingston R.J., Rieder M.J., Shaffer T., Bertucci C., Baier C.N., Rajkumar N., Willa H.T., Daniels M., Downing T.K., Stanaway I.B., et al.
NIEHS-SNPs, environmental genome project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu).
[10]
, Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
BIRC2 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of BIRC2 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about BIRC2 antibody, all related information, articles, resources about BIRC2 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.
Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays.
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MDH
Melanocyte-stimulating hormone receptor
Melanocyte-stimulating hormone receptor
Methylated-DNA--protein-cysteine methylt...
MIA Human
MICA Human
MICB Human
MIF
MIF (clone 4E4)
MIF Human His-N
MIG Human
MIG Mouse
MIP-1a Human
MIP-1a Mouse
MIP-1a Rat
MIP-1b Human
MIP-3b Human
MIP-3b Mouse
MITF (microphthalmia-associated transcri...
MMP-3 Human
MMP-7 Human
MMP-8 Human
MTF1 (metal-regulatory transcription fac...
MXI1 (MAX interactor 1)
MYBL2 (v-myb myeloblastosis viral oncoge...
MYCBP (c-myc binding protein)
MYCL1 (v-myc myelocytomatosis viral onco...
MYCN (v-myc myelocytomatosis viral relat...
NANOG (Nanog homeobox)
NAP-2 Human
NAPA (N-ethylmaleimide-sensitive factor ...
Neuromedin-B receptor
Neuromedin-B receptor
NFkappaB essential modulator
NFkappaB essential modulator
NFKB2 (nuclear factor of kappa light pol...
NFKB2 (nuclear factor of kappa light pol...
NGAL Human
NOTCH3 (Notch homolog 3 (Drosophila))
NRG1 Human
NT-3 Human
Nuclear receptor 0B1
Nuclear receptor subfamily 4, group A, m...
Nuclear receptor subfamily 4, group A, m...
Omentin Human
Orphan G Protein-Coupled Receptor CAD696...
Orphan G Protein-Coupled Receptor CAD696...
OSM Human
OTTHUMP00000018219
OTTHUMP00000018219
OTTHUMP00000018219
OTTHUMP00000018219
P-Sel Human
P40
P504s Human
PARP1 (poly (ADP-ribose) polymerase fami...
Patched 2
PAX2 (paired box gene 2)
PAX3 (paired box gene 3 (Waardenburg syn...
PAX5 (paired box gene 5 (B-cell lineage ...
PAX7 (paired box gene 7)
PAX7 (paired box gene 7)
PDCD4 (programmed cell death 4 (neoplast...
PDGF-BB Human, Yeast
PDGF-BB Mouse
PDI Human
Peflin
Peptidyl-prolyl cis-trans isomerase NIMA...
Peripheral-type benzodiazepine receptor
PEX Human
PfHSP70
PHB (prohibitin)
Pin1 (clone 3G8)
PIN1 Human
PKC-a Human
PKC-d Human
PKC-e Human
PKC-t Human
PL-7 Human
PLA2 IIA Human
Platelet-Derived Growth Factor, AB Heter...
PLGF-1 Human
PLGF-2 Human
POU1F1 (POU domain. class 1. transcripti...
POU1F1 (POU domain. class 1. transcripti...
POU2F2 (POU domain. class 2. transcripti...
PPAR-g Human
PPARA (peroxisome proliferator-activated...
PREB (prolactin regulatory element bindi...
PRKAR1A
ProBMP-2 Human
Programmed cell death protein 8, mitocho...
Programmed cell death protein 8, mitocho...
Programmed cell death protein 8, mitocho...
Protein CYR61
Protein p65
Protein patched homolog 1
Protein SSX4
PTP-1B (Protein Tyrosine Phosphatase1B)
Putative G-protein coupled receptor
Putative G-protein coupled receptor
Putative transmembrane receptor
Putative transmembrane receptor
Putative transmembrane receptor
RAB3A (RAB3A. member RAS oncogene family...
Rantes Human
RAP Rat
Ras-related C3 botulinum toxin substrate...
RB1 (retinoblastoma 1 (including osteosa...
RBPJ (recombination signal binding prote...
Recoverin
REG1-a Human
RELA
Ribonucleoside-diphosphate reductase M2 ...
RTSbeta
RUNX1T1 (runt-related transcription fact...
RUNX2 (runt-related transcription factor...
RXR Alpha Human
RXR-alpha (Retinoid x receptor)
S100A1 Human
S100A11 Human
S100A4 Human
S100b Human
S100P Human
SALF (Stonin 1)
SARS Core 1-49
SARS Core 1-49, 192-220
SARS Core 340-390
SCD (stearoyl-CoA desaturase (delta-9-de...
SCF Human
SCF Human, Sf9
SCF Mouse
SCF Rat
SDF-1a Human
SDF-1a Mouse
SDF-1b Human
SDF-1b Mouse
SEMA4A
Serine protease HTRA2, mitochondrial
Serine/threonine-protein kinase Chk2
Serine/threonine-protein kinase Sgk1
SERPINH1
Serum amyloid P-component
Signal transducer and activator of trans...
SMAD3 (SMAD family member 3)
SMAD6 (SMAD family member 6)
SMAD6 (SMAD family member 6)
SMAD7 (SMAD family member 7)
SMARCB1
SNAP-25 (Synaptosomal-associated protein...
SNAP-25 C.elegans
SOD Human
Somatostatin receptor type 1
Somatostatin receptor type 2
Somatostatin receptor type 2
Somatostatin receptor type 4
Somatostatin receptor type 5
SOX9 (SRY (sex determining region Y)-box...
SPA
SPARC
SSTR4 (somatostatin receptor 4)
Staphylokinase
STAT1 Human
STAT4 (signal transducer and activator o...
Substance-P receptor
Substance-P receptor
T-cell-specific surface glycoprotein CD2...
T.gondii p30
T.pallidum p41 mosaic
TAL1
TAL1 (T-cell acute lymphocytic leukemia ...
TaqDNA
TATA-binding protein-associated phosphop...
TBP (TATA box binding protein)
TCF2 (transcription factor 2. hepatic; L...
TCF4 (transcription factor 4)
TFDP1 (transcription factor Dp-1)
TGF-B 3 Human
Thyroid stimulating hormone receptor
Thyroid stimulating hormone receptor
Thyroid stimulating hormone receptor
TIRP
TIRP
TLR2 (clone 1F10)
TNF receptor-associated factor 6
TNF-b Human
TNFRI Human
TNFRSF10A (tumor necrosis factor recepto...
Toll-like receptor 2
Toll-like receptor 4
Toll-like receptor 4
TOP1 Human
TOP2A (topoisomerase (DNA) II alpha 170k...
tPA Human
TPO Human
TPO Human
TPO Mouse
TRX E.Coli
TRX Yeast
Trypsin Bovine
TSP Human
Tuberin
Tuberin
Tumor necrosis factor receptor superfami...
Tumor necrosis factor receptor superfami...
Tumor necrosis factor receptor superfami...
Tumor necrosis factor receptor superfami...
Tyrosine-protein kinase BTK
Urease
USF1 (upstream transcription factor 1)
VEGF-C Rat
Vim Human
YY1 (YY1 transcription factor)
ZNFN1A1
Products Type:
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Protein
Peptide
Applications:
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Source:
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Bovine
Canine
Chicken
Equine
Feline
Goat
Hamster
Mouse
Porcine
Primate
Rabbit
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Xenopus
Zebrafish
Xreactivity:
Amphibian
Bovine
Canine
Chicken
Drosophila
Equine
Feline
Goat
Hamster
Human
Insect
Mouse
Porcine
Primate
Rabbit
Rat
Sheep
Viral
Xenopus
Zebrafish
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TRITC
Specific Categories
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