BAX antibody, Apoptosis regulator BAX, membrane isoform alpha Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Apoptosis regulator BAX, membrane isoform alpha Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-661-15197

Buy BAX antibody -

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Related Product Names:

- BAX antibody; BAX; Apoptosis regulator BAX, membrane isoform alpha
- Bax alpha

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: BAX	Gene Name Synonym: N/A
Gi #: 388166	NCBI Acc #: AAA03619.1	Swiss Prot Acc #: Q07812
Length (aa): 192	Mol. Weight (Da): 21184	Chrom Location: N/A

Immunogen: Raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax.

Source/Host: Rabbit

Purity/Purification: It is supplied as ion exchange chromatography purified IgG .

Clonality: Polyclonal

Crossreactivity: Human

Format: Phosphate-Buffered Saline, containing 0.02% sodium azide.

Storage: 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.

Stability: Store at -4 degree C for one year.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for BAX ANTIBODY:

IHC, WB: Tested

ELISA, ICC: Not Tested

TESTING: (secondary reagents and protocols )

IHC: Immunohistochemical staining of HL-60 cells using anti-Bax (NT) at 2 ug/ml. ( anti-BAX )

BAX antibody IHC image
BAX

Western Blot: Western blot analysis of Bax in HL-60 cell lysates with anti-Bax (NT) at (A) 1, (B) 2, and (C) 4 ug/ml. ( anti-BAX )

BAX antibody Western Blot image
BAX

BAX ANTIBODY TARGET DESCRIPTION:

Synonym Names for BAX antibody: BAX; Bax alpha

Function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Induces the release of cytochrome c, activation of CASP3, and thereby apoptosis.

Subunit: Homodimers and heterodimers with BCL2, E1B 19K protein, BCL2L1 isoform Bcl-X(L), MCL1 and A1. Interacts with SH3GLB1 and HN.

Subcellular Location: Membrane; single-pass membrane protein.

Tissue Specificity: Expressed in a wide variety of tissues.

Domain: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family (By similarity).

Disease: Defects in BAX are found in some cell lines from hematopoietic malignancies as T-cell acute lymphoblastic leukemia, Burkitt lymphoma, and plasmacytoma.

Similarity: Belongs to the Bcl-2 family.

Apoptosis regulator BAX, membrane isoform alpha reacts with human.

OMIM: 600040; gene. [NCBI / EBI]

Products similar to BAX antibody:

IgG

Bax (ready-to-use), IgG

Bax [2D2] (ready-to-use), IgG

Bax, IgG

BAX (BCL2-associated X protein), IgG

Bax, IgG

PRODUCT INTERACTIONS:

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-2 homologous antagonist/killer, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BAK1, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bak, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bak [TC100], IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bak, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bak (ready-to-use), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Apoptosis regulator Bcl-2, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-2, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl2 [SPM117] (ready-to-use), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl2 [100/D5], IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl2 [124], IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl2 [124] (ready-to-use), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Phospho-Thr56), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Phospho-Ser70), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Ab-56), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Ab-70), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Phospho-Thr56) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-2 (Phospho-Ser70) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL2 (B-cell CLL/lymphoma 2), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-2 Human, Protein (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Anti-Bcl-2, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl2, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-2, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Apoptosis regulator Bcl-X, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL2L1 (BCL2-like 1), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X [SPM165], IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X [2H12], IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-XL (Phospho-Ser62), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-XL (Ab-62), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with BCL-XL (Phospho-Ser62) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Mouse Anti-Human Bcl-xL, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X (ready-to-use), IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X, IgG (GenWay Catalog #: 18-661-15197).

Apoptosis regulator BAX, membrane isoform alpha interacts with Bcl-X (ready-to-use), IgG (GenWay Catalog #: 18-661-15197).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for BAX ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Oltvai,Z.N., Milliman,C.L. and Korsmeyer,S.J., et al.
     Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
[2] , Oltvai Z.N., Milliman C.L., Korsmeyer S.J.
     Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
[3] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[4] , Chittenden T., Flemington C., Houghton A.B., Ebb R.G., Gallo G.J., Elangovan B., Chinnadurai G., Lutz R.J.
     A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.
[5] , Cuddeback S.M., Yamaguchi H., Komatsu K., Miyashita T., Yamada M., Wu C., Singh S., Wang H.-G.
     Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax.
[6] , Guo B., Zhai D., Cabezas E., Welsh K., Nouraini S., Satterthwait A.C., Reed J.C.
     Humanin peptide suppresses apoptosis by interfering with Bax activation.
[7] , Meijerink J.P.P., Mensink E.J.B.M., Wang K., Sedlak T.W., Sloetjes A.W., de Witte T., Waksman G., Korsmeyer S.J.
     Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: BAX antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of BAX antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about BAX antibody, all related information, articles, resources about BAX antibody are being stored on our online database. Let us know if you have questions regarding this product.

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