ACTB antibody, Actin, cytoplasmic 1 Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Actin, cytoplasmic 1 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-661-15259

Buy ACTB antibody -

Size:

Related Product Names:

- ACTB antibody; ACTB; PS1TP5BP1; Actin, cytoplasmic 1
- Beta-actin; Actin, beta

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ACTB	Gene Name Synonym: PS1TP5BP1
Gi #: 12803203	NCBI Acc #: AAH02409.1	Swiss Prot Acc #: P60709
Length (aa): 375	Mol. Weight (Da): 41737	Chrom Location: 7p15-p12

Immunogen: Raised against a 16 amino acid peptide from near the amino-terminus of human b-actin.

Source/Host: Rabbit

Purity/Purification: b-actin antibody is supplied as immunoaffinity purified IgG.

Clonality: Polyclonal

Crossreactivity: Human, mouse, rat

Format: Phosphate-Buffered Saline, containing 0.02% sodium azide.

Storage: 4 degree C for short term (weeks) and -20 degree C for long term. Avoid frequent freeze and thaw.

Stability: Store at -4 degree C for one year.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ACTB ANTIBODY:

WB: Tested

ELISA, ICC, IHC: Not Tested

TESTING: (secondary reagents and protocols )

Western Blot: Western blot analysis of b-actin in HeLa cell lysate with b-actin antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. ( anti-ACTB )

ACTB antibody Western Blot image
ACTB

ACTB ANTIBODY TARGET DESCRIPTION:

Synonym Names for ACTB antibody: ACTB; PS1TP5BP1; Beta-actin; Actin, beta

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Subunit: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with XPO6.

Subcellular Location: Cytoplasm.

Miscellaneous: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.

Similarity: Belongs to the actin family.

Actin, cytoplasmic 1 reacts with human, mouse, rat.

OMIM: 102630; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Adherens junction 04520
KEGG pathway: Cell Communication 01430
KEGG pathway: Focal adhesion 04510
KEGG pathway: Leukocyte transendothelial migration 04670
KEGG pathway: Pathogenic Escherichia coli infection - EHEC 05130
KEGG pathway: Pathogenic Escherichia coli infection - EPEC 05131
KEGG pathway: Regulation of actin cytoskeleton 04810
KEGG pathway: Tight junction 04530

Products similar to ACTB antibody:

IgG

beta Actin (ready-to-use), IgG

actin, beta, IgG

beta Lactamase [3E11.G3], IgG

beta Actin, IgG

beta Lactamase, IgG

Protein

Actin, cytoplasmic 1, Protein

ACTG1 Human, Protein

Actin, cytoplasmic 2, Protein

PRODUCT INTERACTIONS:

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for ACTB ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,, et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
[2] Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,, et al.
     Direct Submission
[3] , Ponte P., Ng S.Y., Engel J., Gunning P., Kedes L.
     Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA.
[4] , Nakajima-Iijima S., Hamada H., Reddy P., Kakunaga T.
     Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns.
[5] , Ohmori H., Toyama S., Toyama S.
     Direct proof that the primary site of action of cytochalasin on cell motility processes is actin.
[6] , Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N., Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S., et al.
     NIEHS-SNPs, environmental genome project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu).
[7] , Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., et al.
     The DNA sequence of human chromosome 7.
[8] , Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., et al.
     Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
[9] , Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.
     Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
[10] , Bienvenut W.V.
     Unpublished observations (JUN-2005).

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Precautions: ACTB antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ACTB antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ACTB antibody, all related information, articles, resources about ACTB antibody are being stored on our online database. Let us know if you have questions regarding this product.

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