|
|
| PECAM-1 (CD31) Antibody, Mouse IgG1 Monoclonal Antibody |
 |
|
|
 |
| Catalog Number: 20-321-175122 |
|
|
|
| Related Product Names:
|
-
PECAM1 antibody; PECAM1; PECAM-1 (CD31)
- MONOCLONAL ANTIBODY TO HUMAN PECAM-1 (CD31); PECAM-1; EndoCAM; GPIIA'; CD31 antigen; PECAM-1; CD31/EndoCAM; Platelet endothelial cell adhesion molecule |
|
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
|
|
| Gene Name: PECAM1 |
Gene Name Synonym: N/A |
Gi #:
435846 |
NCBI Acc #:
AAB28645.1 |
Swiss Prot Acc #:
P16284 |
Length (aa): 78 |
Mol. Weight (Da): 82536 |
Chrom Location: N/A |
|
|
 Clone: BV8
Applications: The antibody can be used for immuno assays and immuno precipitation. Furthermore the antibody is useful for flow cytometry.
Source/Host: Mouse IgG1
Clonality: Monoclonal
Crossreactivity: Human
Format: 1 ml (100 ug/ml) 0.2 um filtered antibody solution in PBS. containing 0.02% sodium azide and 0.1% bovine serum albumin.
Storage: Product should be stored at 4 degree C
Stability: Stable for 1 year
Shipping: Products may be shipped on ice pack or dry ice. |
|
|
|
| PECAM1 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for PECAM1 antibody: PECAM1; MONOCLONAL ANTIBODY TO HUMAN PECAM-1 (CD31); PECAM-1; EndoCAM; GPIIA'; CD31 antigen; PECAM-1; CD31/EndoCAM; Platelet endothelial cell adhesion molecule
This monoclonal antibody binds to human PECAM-1 (platelet endothelial cell adhesion molecule-1; CD31) a specific component of endothelial cell junctions. PECAM-1 is also expressed in platelets and leukocytes.
Function: This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.
Subcellular Location: Membrane; Single-pass type I membrane protein.
Tissue Specificity: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.
Ptm: Phosphorylated on Ser and Tyr residues after cellular activation.
Similarity: Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
PECAM-1 (CD31) reacts with human.
OMIM: 173445; gene. [NCBI / EBI]
Products similar to PECAM1 antibody:
IgG
 CD31 [B493 (158-2B3)], IgG
CD31 [MEM-05], IgG
CD31, IgG
CD31, IgG
CD31 [JC/70A], IgG
|
|
|
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
|
|
| BACKGROUND
REFERENCES for PECAM1 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
[1] Tang,D.G., Chen,Y.Q., Newman,P.J., Shi,L., Gao,X., Diglio,C.A. and Honn,K.V.
Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium
[2] Simmons D.L., Walker C., Power C., Pigott R.
Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen.
[3] Stockinger H., Gadd S.J., Eher R., Majdic O., Kasinrek W., Schreiber W., Strass B., Schnabl E., Knapp W.
Molecular characterization and functional analysis of the leukocyte surface protein CD31.
[4] Newman P.J., Berndt M.C., Gorski J., White J.C. II, Lyman S., Paddock C., Muller W.A.
PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily.
[5] Albelda S.M., Muller W.A., Buck C.A., Newman P.J.
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.
[6] Kirschbaum N.E., Gumina R.J., Newman P.J.
Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain.
[7] Robbins F.-M.Y., Yao H., Hurley C.K., Hartzman R.J.
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
[8] Tang D.G., Chen Y.Q., Newman P.J., Shi L., Gao X., Diglio C.A., Honn K.V.
Identification of PECAM-1 in solid tumor cells and its potential involvement in tumor cell adhesion to endothelium.
[9] Famiglietti J., Sun J., DeLisser H.M., Albelda S.M.
Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificity.
[10] Wang Y., Su X., Sorenson C.M., Sheibani N.
Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms. |
|
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: PECAM1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of PECAM1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about PECAM1 antibody, all related information, articles, resources about PECAM1 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
|
|
|
GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.
|
|
Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
|
|
|
