Ferritin antibody, Ferritin [F31] Antibody, Mouse Monoclonal Antibody

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Ferritin [F31] Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-190049

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Related Product Names:

- Ferritin antibody; Ferritin; 2512; FTL; 134790; P02792; MGC71996; 94033; FTMT; 608847; Q8N4E7; MTF;; Ferritin [F31]
- Mouse monoclonal [F31] to Ferritin; 2512; FTL; 134790; P02792; MGC71996; 94033; FTMT; 608847; Q8N4E7; MTF;; Ferritin light chain

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: Ferritin	Gene Name Synonym: 2512; FTL; 134790; P02792; MGC71996; 94033; FTMT; 608847; Q8N4E7; MTF;
Gi #: N/A	NCBI Acc #: NP_000137.2	Swiss Prot Acc #: P02792
Length (aa): N/A	Mol. Weight (Da): 20020	Chrom Location: N/A

Clone: F31

Isotype: IgG2b

Immunogen: This clone has been derived from hybridization of SP2/0 myeloma cells with spleen cells of Balb/c mice immunised with purified human ferritin.

Antigen Species: Human

Target: Ferritin

Concentration: 2.4 mg/ml

Purification Note: Purity is tested by electrophoresis.

Storage Buffer: Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide

Application Note: ELISA: Use at an assay dependent dilution. Can be used with 20-272-190048 (capture). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Source/Host: Mouse

Purity/Purification: Protein G purified

Clonality: Monoclonal

Crossreactivity: Human - Not yet tested in other species

Format: Liquid

Storage: Keep as concentrated solution, aliquot and store at 4C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for FERRITIN ANTIBODY:

ELISA: Tested

TESTING: (secondary reagents and protocols )

Not Available

FERRITIN ANTIBODY TARGET DESCRIPTION:

Synonym Names for Ferritin antibody: Ferritin; 2512; FTL; 134790; P02792; MGC71996; 94033; FTMT; 608847; Q8N4E7; MTF;; Mouse monoclonal [F31] to Ferritin; 2512; FTL; 134790; P02792; MGC71996; 94033; FTMT; 608847; Q8N4E7; MTF;; Ferritin light chain

Ferritin is an iron storage protein synthesized by all human cells, with highest concentration in liverparenchymal cells.

Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

Subunit: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.

Disease: Defects in FTL are the cause of hereditary hyperferritinemia-cataract syndrome (HHCS) [MIM:600886]. It is an autosomal dominant disease characterized by early-onset bilateral cataract. Affected patients have elevated level of circulating ferritin. HHCS is caused by mutations in the iron responsive element (IRE) of the FTL gene.

Disease: Defects in FTL are the cause of neuroferritinopathy [MIM:606159]; also known as adult-onset basal ganglia disease. It is a movement disorder with heterogeneous presentations starting in the fourth to sixth decade. It is characterized by a variety of neurological signs including parkinsonism, ataxia, corticospinal signs, mild nonprogressive cognitive deficit and episodic psychosis. It is linked with decreased serum ferritin levels.

Similarity: Belongs to the ferritin family.

Similarity: Contains 1 ferritin-like diiron domain.

Ferritin [F31] reacts with human - not yet tested in other species.

OMIM: 134790; gene. [NCBI / EBI]
600886; phenotype. [NCBI / EBI]
606159; phenotype. [NCBI / EBI]

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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

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Precautions: Ferritin antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of Ferritin antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Ferritin antibody, all related information, articles, resources about Ferritin antibody are being stored on our online database. Let us know if you have questions regarding this product.

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