FGF2 antibody, FGF2 [FB-8] Antibody, Mouse Monoclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

FGF2 [FB-8] Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-190207

Buy FGF2 antibody -

Volume:

Related Product Names:

- FGF2 antibody; FGF2; 2247; FGF2; 134920; P09038; BFGF; FGFB; HBGH-2;; FGF2 [FB-8]
- Mouse monoclonal [FB - 8] to FGF2; 2247; FGF2; 134920; P09038; BFGF; FGFB; HBGH-2;; Heparin-binding growth factor 2

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: FGF2	Gene Name Synonym: 2247; FGF2; 134920; P09038; BFGF; FGFB; HBGH-2;
Gi #: N/A	NCBI Acc #: NP_001997.5	Swiss Prot Acc #: P09038
Length (aa): N/A	Mol. Weight (Da): 17254	Chrom Location: N/A

Clone: FB-8

Isotype: IgG1

Immunogen: Recombinant full length protein (Human).

Antigen Species: Human

Specificity: Does not cross-react with human fibroblast growth factor - acidic (aFGF).

Target: FGF2

Concentration: 2.2 mg/ml

Storage Buffer: Preservative: None Constituents: 0.01M PBS. pH 7.4

Application Note: Dot: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. Neut: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 18 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Source/Host: Mouse

Purity/Purification: Protein A purified

Clonality: Monoclonal

Crossreactivity: Cross-reacts with Human and Cow. Not yet tested in other species.

Storage: For continuous use, store at 2-8C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for FGF2 ANTIBODY:

Dot, ELISA, Neut, RIA, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

FGF2 ANTIBODY TARGET DESCRIPTION:

Synonym Names for FGF2 antibody: FGF2; 2247; FGF2; 134920; P09038; BFGF; FGFB; HBGH-2;; Mouse monoclonal [FB - 8] to FGF2; 2247; FGF2; 134920; P09038; BFGF; FGFB; HBGH-2;; Heparin-binding growth factor 2

Fibroblast growth factors (FGFs) are members of a family of polypeptides that are potent regulators of cell proliferation, differentiation and function. The FGF family consists of seven members with 30-50% sequence identity at the amino acid level and with conservation of the positions of two cysteine residues. The factors are designated FGF-1 through FGF-7; the names FGF acidic and basic are used for FGF-1 and FGF-2, respectively. Acidic and basic fibroblast growth factor (aFGF and bFGF, respectively) are members of a small family of heparin binding growth factors (HBGF). Comparisons of the primary structure have shown that aFGF and bFGF are closely related mitogens with 55% homology. When isolated from natural sources, bFGF usually has an apparent mass of about 18 kDa, but a variety of larger forms, up to 24 kDa, can exist. Natural bFGF exists in three forms, the 154 amino-acid form and two truncated versions of 146 and 131 amino acids lacking the N-terminal 9 and 24 residues, respectively. Depending on the organ from which it is purified, either the complete or truncated forms of bFGF may be present. In pituitary and brain the complete form predominates, in kidney and corpus luteum only the truncated form can be detected, and in adrenal glands, both forms coexist. Human and bovine bFGF are nearly identical in sequence, differing at only two positions. The largest (154 aa) form of both human and bovine aFGF share all but 12 amino acids. FGFs play crucial roles in normal development, in the maintenance of tissues, and in wound healing and repair. They have been implicated in a wide range of pathological conditions, including tumorigenesis and metastasis. Both aFGF and bFGF exert their mitogenic influence via saturable high-affinity receptors on a variety of cells of mesodermal and neuroectodermal origin, including endothelial cells, smooth muscle cells, fibroblasts, gliomas, chondrocytes, hepatocytes, epithelial cells, and myoblasts. As expected from the sequence homology between the acidic and basic forms of FGF and from their ability to support the proliferation in vitro of the same spectrum of target cells, both aFGF and bFGF interact with the same cell surface receptor.

Function: The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

Subunit: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2.

Miscellaneous: This protein binds heparin more strongly than does aFGF.

Similarity: Belongs to the heparin-binding growth factors family.

FGF2 [FB-8] reacts with cross-reacts with human and cow. not yet tested in other species..

OMIM: 134920; gene. [NCBI / EBI]

Products similar to FGF2 antibody:

IgG

FGF basic, IgG

FGFR1 beta [M17A3], IgG

FGFR1 [M17D10], IgG

FGF basic [MC-GF1], IgG

FGF basic [F-343], IgG

Protein

FGF BASIC, Protein

FGF-2 Bovine, Protein

FGF-23 Human, Protein

FGF-2 Human, sf9, Protein

FGFR1 Human, Protein

PRODUCT INTERACTIONS:

FGF2 [FB-8] interacts with CASPASE-1, IgG (GenWay Catalog #: 20-272-190207).

FGF2 [FB-8] interacts with Caspase 1 [14F468], IgG (GenWay Catalog #: 20-272-190207).

FGF2 [FB-8] interacts with Rabbit anti Caspase 1 (CT), IgG (GenWay Catalog #: 20-272-190207).

FGF2 [FB-8] interacts with Rabbit anti Caspase 1 (Middle), IgG (GenWay Catalog #: 20-272-190207).

FGF2 [FB-8] interacts with Caspase 1, IgG (GenWay Catalog #: 20-272-190207).

FGF2 [FB-8] interacts with Caspase 1 (ready-to-use), IgG (GenWay Catalog #: 20-272-190207).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: FGF2 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of FGF2 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about FGF2 antibody, all related information, articles, resources about FGF2 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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