P Cadherin antibody, P Cadherin [NCC-CAD-299] Antibody, Mouse Monoclonal Antibody

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P Cadherin [NCC-CAD-299] Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-190755

Buy P Cadherin antibody -

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Related Product Names:

- P Cadherin antibody; P Cadherin; Cadherin 3 Cadherin-3 precursor Cadp Calcium-dependent adhesion protein placental CDHP HJMD P-cadherin (placental) PCAD Placenta; P Cadherin [NCC-CAD-299]
- Mouse monoclonal [NCC-CAD-299] to P cadherin; Cadherin 3 Cadherin-3 precursor Cadp Calcium-dependent adhesion protein placental CDHP HJMD P-cadherin (placental) PCAD Placental cadherin; Cadherin-3

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: P Cadherin	Gene Name Synonym: Cadherin 3 Cadherin-3 precursor Cadp Calcium-dependent adhesion protein placental CDHP HJMD P-cadherin (placental) PCAD Placenta
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: P22223
Length (aa): N/A	Mol. Weight (Da): 91418	Chrom Location: N/A

Clone: NCC-CAD-299

Isotype: IgG1

Immunogen: Human epidermal carcinoma cell line A431.

Antigen Species: Human

Specificity: Human P Cadherin. Inhibits P Cadherin dependent cell-cell contact.

Target: P Cadherin

Localization: Type I membrane protein

Concentration: Lot specific and is stated on the vial.

Storage Buffer: Phosphate-buffered saline, pH 7.4 containing 1% BSA

Application Note: For IHC-Fr: Use at a concentration of 5-10 ug/ml. For Inhib: Use at a concentration of 100 ug/ml. For WB: Use at a concentration of 5-10 ug/ml. Predicted molecular weight: 91.4 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

Cellular Localization: Type I membrane protein

Source/Host: Mouse

Clonality: Monoclonal

Crossreactivity: Human - Not yet tested in other species.

Format: Liquid

Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for P CADHERIN ANTIBODY:

IHC-Fr, Inhib, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

P CADHERIN ANTIBODY TARGET DESCRIPTION:

Synonym Names for P Cadherin antibody: P Cadherin; Cadherin 3 Cadherin-3 precursor Cadp Calcium-dependent adhesion protein placental CDHP HJMD P-cadherin (placental) PCAD Placenta; Mouse monoclonal [NCC-CAD-299] to P cadherin; Cadherin 3 Cadherin-3 precursor Cadp Calcium-dependent adhesion protein placental CDHP HJMD P-cadherin (placental) PCAD Placental cadherin; Cadherin-3

Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subunit: Interacts with CDCP1.

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines.

Disease: Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.

Disease: Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.

Similarity: Contains 5 cadherin domains.

P Cadherin [NCC-CAD-299] reacts with human - not yet tested in other species..

OMIM: 114021; gene. [NCBI / EBI]
225280; phenotype. [NCBI / EBI]
601553; phenotype. [NCBI / EBI]

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: P Cadherin antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of P Cadherin antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about P Cadherin antibody, all related information, articles, resources about P Cadherin antibody are being stored on our online database. Let us know if you have questions regarding this product.

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