14-3-3 beta + zeta antibody, 14-3-3 beta + zeta [22-IID8B] Antibody, Mouse Monoclonal Antibody

Alphabetical Listing of Primary Antibodies:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Alphabetical Listing of Proteins:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Peptides \| Secondary Antibodies \| ELISA Kits

14-3-3 beta + zeta [22-IID8B] Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-190773

Buy 14-3-3 beta + zeta antibody -

Size:

Related Product Names:

- 14-3-3 beta + zeta antibody; 14-3-3 beta + zeta; 14-3-3 beta + zeta [22-IID8B]
- Mouse monoclonal [22 - IID8B] to 14 - 3 - 3 beta + zeta; 14-3-3 protein beta/alpha

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: 14-3-3 beta + zeta	Gene Name Synonym: N/A
Gi #: N/A	NCBI Acc #: NP_003395.1	Swiss Prot Acc #: P31946
Length (aa): N/A	Mol. Weight (Da): 28082	Chrom Location: N/A

Clone: 22-IID8B

Isotype: IgG

Immunogen: Lysed transformed amnion cells (AMA) (Human).

Antigen Species: Human

Positive Control: HeLa cell lysate

Target: 14-3-3 beta + zeta

Localization: Cytoplasmic

Storage Buffer: Preservative: NoneConstituents: 50% Glycerol, PBS, 0.1mM PMSF. pH 7.2

Application Note: ICC: Use at an assay dependent dilution. IHC: Use at a dilution of 1/50. WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 29 and 30 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Cellular Localization: Cytoplasmic

Source/Host: Mouse

Purity/Purification: Protein G purified

Clonality: Monoclonal

Crossreactivity: Cross-reacts with Human, Mouse, Rat, Cow, Dog, Monkey, Pig, Rabbit and Sheep. Not yet tested in other species.

Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for 14-3-3 BETA + ZETA ANTIBODY:

ICC, IHC, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

14-3-3 BETA + ZETA ANTIBODY TARGET DESCRIPTION:

Synonym Names for 14-3-3 beta + zeta antibody: 14-3-3 beta + zeta; Mouse monoclonal [22 - IID8B] to 14 - 3 - 3 beta + zeta; 14-3-3 protein beta/alpha

14-3-3 proteins are highly conserved proteins which play a role in both signal transduction and progression through the cell cycle by binding to and regulating several different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms: alpha, beta, gamma, delta, epsilon, zeta, and eta. An eighth subtype, termed theta has been found in rat brain. The 14-3-3 proteins exist in vitro and in vivo as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. 14-3-3 proteins are localized in the cytoplasm of neurons in the cerebral cortex and are axonally transported to the nerve terminals. They may be present at lower levels in various other eukaryotic tissues. Northern blot analysis has shown expression of the eta chain in cultured cell lines derived from various tumors.

Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Subunit: Homodimer, and heterodimer with YWHAG, YWHAE and YWHAQ. Interacts with SSH1 and TORC2/CRTC2.

Subcellular Location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Ptm: Isoform alpha differs from isoform beta in being phosphorylated (By similarity).

Ptm: Isoform Short contains a N-acetylmethionine at position 1 (By similarity).

Similarity: Belongs to the 14-3-3 family.

14-3-3 beta + zeta [22-IID8B] reacts with cross-reacts with human, mouse, rat, cow, dog, monkey, pig, rabbit and sheep. not yet tested in other species..

OMIM: 601289; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Cell cycle 04110
Reactome Event:Apoptosis 109581
Reactome Event:Signaling by EGFR 177929
Reactome Event:Signaling by Insulin receptor 74752
Reactome Event:Signalling by NGF 166520

Products similar to 14-3-3 beta + zeta antibody:

IgG

14-3-3 beta + zeta [4E2], IgG

PRODUCT INTERACTIONS:

14-3-3 beta + zeta [22-IID8B] interacts with Bcl-2-like protein 11, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with BIM, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with BIM (Phospho-Ser65), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with BIM (Ab-65), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with BIM(Phospho-Ser69/65) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Bim (ready-to-use), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Bim, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with p27/kip1, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with p27 KIP1 [DCS-72.F6], IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with p27Kip1 (Phospho-Thr187), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with p27Kip1 (Ab-10) Antibody, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with p27Kip1 (Phospho-Thr187) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with PKCK2 (clone 3G1), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CK2a Zea Mays, Protein (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CK2a Human, Protein (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Casein kinase II subunit alpha, Protein (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CKII ALPHA, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CASEIN KINASE 2 ALPHA 1, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CK2a His Human, Protein (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Protein kinase Casein Kinase 2 alpha, Protein (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with CKII alpha, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with KIF23 (kinesin family member 23), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with KIF5B (kinesin family member 5B), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with RAC [23A8], IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with RACGAP1 (Rac GTPase activating protein 1), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with c-Raf phospho Y340, Y341, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with c-Raf phospho S338, Y340, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with c-Raf phospho S259, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with RAF1, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with RAF1 [410], IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Raf1 (Phospho-Ser259), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Raf1 (Ab-259), IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Raf1 (Phospho-Ser259) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Raf-1, N-terminal, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with Anti-Raf-1 pS239, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with c-Raf phospho S43 antibody, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with RAF-1, IgG (GenWay Catalog #: 20-272-190773).

14-3-3 beta + zeta [22-IID8B] interacts with c-Raf phospho S621, IgG (GenWay Catalog #: 20-272-190773).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: 14-3-3 beta + zeta antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of 14-3-3 beta + zeta antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about 14-3-3 beta + zeta antibody, all related information, articles, resources about 14-3-3 beta + zeta antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.

Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays.



GenWay Biotech, Inc. 6777 Nancy Ridge Drive, San Diego, CA 92121 Tel: (858)458-0866 Fax: (858)458-0833 Email: sales@genwaybio.com www.genwaybio.com ©1998 - 2010 GenWay Biotech, Inc. - All Rights Reserved