Ubiquitin antibody, Ubiquitin [Ubi-1] Antibody, Mouse Monoclonal Antibody

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Ubiquitin [Ubi-1] Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-193033

Buy Ubiquitin antibody -

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Related Product Names:

- Ubiquitin antibody; Ubiquitin; 29979; UBQLN1; 605046; Q9UMX0; DA41; DSK2; FLJ90054; PLIC-1; XDRP1;; Ubiquitin [Ubi-1]
- Mouse monoclonal to Ubiquitin; 29979; UBQLN1; 605046; Q9UMX0; DA41; DSK2; FLJ90054; PLIC-1; XDRP1;; Ubiquitin

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: Ubiquitin	Gene Name Synonym: 29979; UBQLN1; 605046; Q9UMX0; DA41; DSK2; FLJ90054; PLIC-1; XDRP1;
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: P62988
Length (aa): N/A	Mol. Weight (Da): 8565	Chrom Location: N/A

Clone: Ubi-1

Isotype: IgG1

Light chain: kappa

Immunogen: purified ubiquitin conjugated with glutaraldehyde to keyhole limpet hemocyanin.

Specificity: Recognizes ubiquitinated cytoplasmic inclusion bodies.

Target: Ubiquitin

Concentration: Ascites

Storage Buffer: Ascitic fluid with 10 mM sodium azide

Application Note: ELISA: Use at an assay dependent dilution. ICC/IF: 1/500. IHC-P: Use at a dilution of 1/1000. IHC-Fr: Use at a dilution of 1/1000. WB: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Source/Host: Mouse

Purity/Purification: Unpurified

Clonality: Monoclonal

Crossreactivity: Reacts with human, bovine, mouse, chicken, Drosophila, C. elegans, and Arabidopsis thaliana (plant) ubiquitin and ubiquitinated proteins in ELISA reactions. This antibody recognizes polyubiquitin chains much more strongly than monoubiquitinated molecules or free ubiquitin.

Format: Liquid

Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for UBIQUITIN ANTIBODY:

ELISA, ICC, IF, IHC, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

UBIQUITIN ANTIBODY TARGET DESCRIPTION:

Synonym Names for Ubiquitin antibody: Ubiquitin; 29979; UBQLN1; 605046; Q9UMX0; DA41; DSK2; FLJ90054; PLIC-1; XDRP1;; Mouse monoclonal to Ubiquitin; 29979; UBQLN1; 605046; Q9UMX0; DA41; DSK2; FLJ90054; PLIC-1; XDRP1;; Ubiquitin

Ubiquitin is a highly conserved protein of about 8.5 kDa molecular weight, which has a normal role in the targeting of proteins for proteolytic degradation. To perform this function, the protein to be degraded is first covalently attached to the C-terminus of ubiquitin, and the ubiquitinated complex is then recognized by a complex of degradative enzymes. Interestingly, ubiquitin also becomes covalently bonded to many types of pathological inclusions, which appear to be resistant to normal degradation. Therefore, ubiquitin antibodies are very useful for studies of these inclusions. For example, the neurofibrillary tangles and paired helical filaments diagnostic of Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease are all heavily ubiquitinated and can be readily visualized with ubiquitin antibodies.

Function: Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair.

Subcellular Location: Cytoplasm. Nucleus.

Ptm: Several types of polymeric chains can be formed, depending on the lysine used for the assembly.

Miscellaneous: Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat, here in human a Val. Some ubiquitin genes contain a single copy of ubiquitin fused to a ribosomal protein (either L40 or S27a).

Similarity: Belongs to the ubiquitin family.

Ubiquitin [Ubi-1] reacts with reacts with human, bovine, mouse, chicken, drosophila, c. elegans, and arabidopsis thaliana (plant) ubiquitin and ubiquitinated proteins in elisa reactions. this antibody recognizes polyubiquitin chains much more strongly than monoubiquitinated molecules or free ubiquitin..

OMIM: 191321; gene. [NCBI / EBI]
191339; gene. [NCBI / EBI]
191340; gene. [NCBI / EBI]
191343; gene. [NCBI / EBI]

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PRODUCT INTERACTIONS:

Ubiquitin [Ubi-1] interacts with CDC6 cell division cycle 6 homolog (S. cerevisiae) (CDC6), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with CDC-6 Human, Protein (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with Anti-GGA-1 (Rabbit), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MCM7 (minichromosome maintenance complex component 7), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MCM7, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MDM2 [2A10], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MDM2 [SMP14], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with Rabbit anti Mouse MDM2 pS185, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MDM2 [HDM2-323], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MDM2 [MD-219], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MDM2 (ready-to-use), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MYO6, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with MYO6 [MUD-19], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with ORC1 [7F6/1], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with ORC1 [TK 1/2], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with ORC1, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with Cellular tumor antigen p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 Human, Protein (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53M Human, Protein (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [SP5], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 phospho S15, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-13], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-7], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [Pab240], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [D01], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [3F301], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-7] (ready-to-use), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [BP53-12], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with I-kappaB-alpha (Phospho-Ser32/Ser36), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser15), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser46), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser315), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Ab-15), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Ab-46), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Ab-315), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser15) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser46) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (Phospho-Ser315) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with TP53 (tumor protein p53 (Li-Fraumeni syndrome)), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (a.a. 32-79), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (a.a. 88-109), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 (a.a. 306-393), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with Mouse p53, Wild Type, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with Human p53 Oncogene, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [B20.1 (BP 53.122)] antibody (ready-to-use), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 AIP1, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [BP53-12] (FITC), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-2], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-1], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with P53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [B20.1 (BP 53.122)] antibody (FITC), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with P53 [SP5] (ready-to-use), IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-1], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [B449], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [Pab240], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [Pab1801], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [D01], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53 [DO-2], IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with p53, IgG (GenWay Catalog #: 20-272-193033).

Ubiquitin [Ubi-1] interacts with ZNF385 (zinc finger protein 385), IgG (GenWay Catalog #: 20-272-193033).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: Ubiquitin antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of Ubiquitin antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Ubiquitin antibody, all related information, articles, resources about Ubiquitin antibody are being stored on our online database. Let us know if you have questions regarding this product.

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