ESA antibody, ESA [B29.1 (VU-ID9)] (Biotin) Antibody, Mouse Monoclonal Antibody

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ESA [B29.1 (VU-ID9)] (Biotin) Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-272-193594

Buy ESA antibody -

Volume:

Related Product Names:

- ESA antibody; ESA; 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;; ESA [B29.1 (VU-ID9)] (Biotin)
- Mouse monoclonal [B29.1 VU-ID9] to Epithelial Specific Antigen (Biotin); 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;; Tumor-associated calcium signal transducer 1

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ESA	Gene Name Synonym: 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;
Gi #: N/A	NCBI Acc #: NP_002345.1	Swiss Prot Acc #: P16422
Length (aa): N/A	Mol. Weight (Da): 34932	Chrom Location: N/A

Clone: B29.1 (VU-ID9)

Isotype: IgG1

Immunogen: Small cell lung carcinoma cells

Specificity: This antibody reacts with a 40 kD cell surface glycoprotein called epithelial specific antigen (ESA). It reacts with the same molecule which is also detected by antibodies such as 17-1A, AUA1, KS1/4, Ber-EP4, 323/A3, MOC-31, GA733, HEA125 and others.

Positive Control: Breast, Colon Carcinoma and Tonsil

Target: ESA

Conjugation: Biotin

Concentration: 0.2 mg/ml

Storage Buffer: Phosphate-buffered saline, pH 7.2, containing 0.2%BSA and 0.09% sodium azide.

Application Note: For FACS: Use at 1-5 ug/ml per 10^6 cells. For WB: Use at 1-5µg/ml. For IHC-P: used at a dilution of 1:50-1:60. To differentiate between mesothelioma and carcinoma. Digestion with pepsin at 1mg/ml must be preformed. Prolonged fixation in buffered formalin can destroy the epitope. The optimal conditions should be determined by the individual laboratory.

Source/Host: Mouse

Purity/Purification: Protein G affinity purified

Clonality: Monoclonal

Crossreactivity: Human - Does not cross react with rat - Not yet tested in other species

Format: Liquid

Storage: Keep as concentrated solution, aliquot and store at 4C. Do not freeze.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ESA ANTIBODY:

FACS, IHC-P, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

ESA ANTIBODY TARGET DESCRIPTION:

Synonym Names for ESA antibody: ESA; 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;; Mouse monoclonal [B29.1 VU-ID9] to Epithelial Specific Antigen (Biotin); 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;; Tumor-associated calcium signal transducer 1

EGP40 is a 40kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas.Esa1 acetylates lysine residues of the histone H4 tail in S. cerevisiae. Acetylation of histones gives a specific tag for epigenetic transcription activation - acetylation of histone H4 is essential for DNA double-strand break repair. ESA1 is required for cell cycle progression, it reportedly distinguishes adenocarcinomas from pleural mesotheliomas.

Function: GA733 tumor-associated antigen gene family may function as growth factor receptors.

Subunit: Monomer.

Subcellular Location: Membrane; Single-pass type I membrane protein.

Tissue Specificity: This protein is expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas.

Similarity: Contains 1 thyroglobulin type-1 domain.

ESA [B29.1 (VU-ID9)] (Biotin) reacts with human - does not cross react with rat - not yet tested in other species.

OMIM: 185535; gene. [NCBI / EBI]

Products similar to ESA antibody:

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Flotillin 2 / FLOT2 (C Term), IgG

MYST, IgG

EpCAM [AUA1], IgG

EpCAM [VU-1D9], IgG

CD326, IgG

Native_Protein

Epithelial Cell Extract, Human, Native_Protein

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ESA antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ESA antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ESA antibody, all related information, articles, resources about ESA antibody are being stored on our online database. Let us know if you have questions regarding this product.

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