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L1 [MAC387] Antibody, Mouse Monoclonal Antibody Printer Friendly Datasheet
Catalog Number: 20-272-193980
Buy L1 antibody - Size:   
  Related Product Names:
- L1 antibody; L1; MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387; L1 [MAC387]
- Mouse Monoclonal to Human Macrophages Sample; MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387; Protein S100-A9
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: L1  Gene Name Synonym: MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387

 Gi #: N/A

 NCBI Acc #: NP_002956.1

 Swiss Prot Acc #: P06702

 Length (aa): N/A

 Mol. Weight (Da): 13242

 Chrom Location: N/A
 Clone: MAC387

 Isotype: IgG1

 Immunogen: Human monocytes

 Antigen Species: Human

 Specificity: Recognises the L1 or Calprotectin molecule, an intracytoplasmic antigen comprised of a 12kD alpha chain and a 14kD beta chain.

 Positive Control: Human spleen

 Target: L1

 Concentration: 1.0 mg/ml

 Purification Note: From hybridoma culture supernatant

 Storage Buffer: Buffer contains 0.09% sodium azide

 Application Note: For Flow Cytometry: Use at a dilution of 1:50 - 1:100. For IHC-Fr and IHC-P: Use at a dilution of 1:100 - 1:200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. ** This product requires protein digestion pre-treatment e.g. trypsin, 0.1% for 10 minutes or antigen retrieval using heat treatment prior to staining of paraffin sections.

 Myeloma: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line

 Source/Host: Mouse

 Purity/Purification: Protein G affinity purified

 Clonality: Monoclonal

 Crossreactivity: Cat, dog, ox, pig horse, rabbit, guinea pig, rat, cynomolgus monkey, baboon, rhesus monkey - Not yet tested in other species

 Format: Liquid

 Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for L1 ANTIBODY:
 FACS, IHC-Fr, IHC-P: Tested
 TESTING: (secondary reagents and protocols )
 Not Available
 L1 ANTIBODY TARGET DESCRIPTION:
Synonym Names for L1 antibody: L1; MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387; Mouse Monoclonal to Human Macrophages Sample; MIF NIF P14 CAGB CFAG CGLB L1AG LIAG MRP14 60B8AG MAC387; Protein S100-A9

The L1 protein is a member of the S100 family of proteins. These proteins are limited to the cytoplasm and/or nucleus of a wide variety of cells. They regulate more than a few cellular processes, including differentiation and cell cycle progression. Cystic fibrosis is linked to altered expression of this protein.

Function: Expressed by macrophages in acutely inflammated tissues and in chronic inflammations. Seem to be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells.

Subunit: Interacts with CEACAM3 in a calcium-dependent manner.

Miscellaneous: Has been shown to bind calcium.

Similarity: Belongs to the S-100 family.

Similarity: Contains 2 EF-hand domains.

L1 [MAC387] reacts with cat, dog, ox, pig horse, rabbit, guinea pig, rat, cynomolgus monkey, baboon, rhesus monkey - not yet tested in other species.

OMIM: 123886; gene. [NCBI / EBI]

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 PRODUCT INTERACTIONS:
 L1 [MAC387] interacts with beta 1 Arrestin phospho S412, IgG (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Integrin-linked kinase(ILK1): Human, Recombinant, E Coli, Protein (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Integrin-linked kinase (ILK1): Human, Recombinant, E Coli, Protein (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Integrin-linked kinase (ILK1): Human, Recombinant, E Coli, Protein (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Integrin-linked kinase (ILK1): Human, Recombinant, E Coli, Protein (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Serine/threonine-protein kinase PAK 7, IgG (GenWay Catalog #: 20-272-193980).
 L1 [MAC387] interacts with Serine/threonine-protein kinase PAK 7, Protein (GenWay Catalog #: 20-272-193980).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: L1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of L1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about L1 antibody, all related information, articles, resources about L1 antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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