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| alpha 2 Catenin Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-272-195398 |
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| Related Product Names:
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alpha 2 Catenin antibody; alpha 2 Catenin; 1496; CTNNA2; 114025; P26232; CAP-R; CAPR; CTNR;; alpha 2 Catenin
- Rabbit polyclonal to alpha 2 Catenin; 1496; CTNNA2; 114025; P26232; CAP-R; CAPR; CTNR;; Catenin alpha-1 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: alpha 2 Catenin |
Gene Name Synonym: 1496; CTNNA2; 114025; P26232; CAP-R; CAPR; CTNR; |
Gi #:
N/A |
NCBI Acc #:
N/A |
Swiss Prot Acc #:
Q59I72 |
Length (aa): N/A |
Mol. Weight (Da): 100173 |
Chrom Location: N/A |
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 Isotype: IgG
Immunogen: Synthetic peptide: DLANRFKEFGKKMVKL conjugated to KLH, corresponding to amino acids 171-186 of Human alpha 2 Catenin.
Antigen Species: Human
Specificity: Anti-alpha-N-Catenin recognizes alpha-N-catenin (102 kDa) by immunoblotting.Staining of the alpha-N-catenin band in immunoblotting is specifically inhibited with the alpha-N-catenin immunizing peptide (human, amino acids 171-186).
Target: alpha 2 Catenin
Storage Buffer: Preservative: 15mM Sodium Azide; Constituents: 0.01M PBS. pH 7.4
Application Note: WB: Use at a dilution of 1/1000. Detects a band of approximately 102 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Source/Host: Rabbit
Purity/Purification: IgG fraction
Clonality: Polyclonal
Crossreactivity: Cross-reacts with Human. Expected to cross-react with Mouse (93% identity with immunogen) and Chicken (93% identity with immunogen) due to sequence homology. Not yet tested in other species.
Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for ALPHA 2 CATENIN ANTIBODY: |
| WB: Tested |
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| ALPHA 2 CATENIN ANTIBODY TARGET DESCRIPTION: |
Synonym Names for alpha 2 Catenin antibody: alpha 2 Catenin; 1496; CTNNA2; 114025; P26232; CAP-R; CAPR; CTNR;; Rabbit polyclonal to alpha 2 Catenin; 1496; CTNNA2; 114025; P26232; CAP-R; CAPR; CTNR;; Catenin alpha-1
The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.
Function: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. May play a crucial role in cell differentiation (By similarity).
Subunit: Binds MLLT4 and F-actin. Interacts directly with CTNNB1 and PSEN1 to form part of the PSEN1/cadherin/catenin adhesion complex. Interacts with ARHGAP21 and with JUB (By similarity).
Subcellular Location: Cytoplasm, cytoskeleton (By similarity). Cell junction, adherens junction (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cell junction (By similarity). Note=Found at cell-cell boundaries and probably at cell-matrix boundaries (By similarity).
Ptm: Sumoylated (By similarity).
Similarity: Belongs to the vinculin/alpha-catenin family.
alpha 2 Catenin reacts with cross-reacts with human. expected to cross-react with mouse (93% identity with immunogen) and chicken (93% identity with immunogen) due to sequence homology. not yet tested in other species..
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: alpha 2 Catenin antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of alpha 2 Catenin antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about alpha 2 Catenin antibody, all related information, articles, resources about alpha 2 Catenin antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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