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Peptides  |  Secondary Antibodies  |  ELISA Kits
ErbB4 Antibody, Rabbit Polyclonal Antibody Printer Friendly Datasheet
Catalog Number: 18-272-196265
Buy ErbB4 antibody - Volume:   
  Related Product Names:
- ErbB4 antibody; ErbB4; 2066; ERBB4; 600543; Q15303; HER4; MGC138404;; ErbB4
- Rabbit polyclonal to ErbB 4; 2066; ERBB4; 600543; Q15303; HER4; MGC138404;; Receptor tyrosine-protein kinase erbB-4
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: ErbB4  Gene Name Synonym: 2066; ERBB4; 600543; Q15303; HER4; MGC138404;

 Gi #: N/A
 NCBI Acc #: NP_001036064.1
 Swiss Prot Acc #: Q15303

 Length (aa): N/A
 Mol. Weight (Da): 146808
 Chrom Location: N/A
 Isotype: IgG

 Immunogen: Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (C terminal).

 Antigen Species: Human

 Positive Control: Breast carcinoma or skeletal muscle

 Target: ErbB4

 Localization: Type I membrane protein

 Concentration: 0.2 mg/ml

 Storage Buffer: Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

 Application Note: IHC-P: Use at a dilution of 1/50 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 146.8 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

 Cellular Localization: Type I membrane protein

 Source/Host: Rabbit

 Purity/Purification: Immunogen affinity purified

 Clonality: Polyclonal

 Crossreactivity: Cross-reacts with Human and Mouse. Not yet tested in other species.

 Format: Liquid

 Storage: Keep as concentrated solution, aliquot and store at 4C. Do not freeze.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for ERBB4 ANTIBODY:
 IHC-P, IP, WB: Tested
 TESTING: (secondary reagents and protocols )
 Not Available
 ERBB4 ANTIBODY TARGET DESCRIPTION:
Synonym Names for ErbB4 antibody: ErbB4; 2066; ERBB4; 600543; Q15303; HER4; MGC138404;; Rabbit polyclonal to ErbB 4; 2066; ERBB4; 600543; Q15303; HER4; MGC138404;; Receptor tyrosine-protein kinase erbB-4

ErbB 4 is the fourth member of class I receptor kinase family. EbbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum. Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361. Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3.

Function: Specifically binds and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. Interaction with these factors induces cell differentiation. Not activated by EGF, TGF-A, and amphiregulin.

Catalytic Activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Subunit: Homodimer or heterodimer with each of the other ERBB receptors (Potential). Interacts with PDZ domains of DLG2, DLG3, DLG4 and the syntrophin SNTB2. Interacts with CBFA2T3, MUC1 and WWOX.

Subcellular Location: Membrane; Single-pass type I membrane protein.

Tissue Specificity: Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A and isoform JM-B are expressed in cerebellum, but only the isoform JM-B is expressed in the heart.

Domain: The WW-binding motifs mediate interaction with WWOX.

Ptm: Isoform JM-A is processed but not isoform JM-B. So, they respectively represent cleavable and non-cleavable forms of the receptor.

Ptm: Ligand-binding increases phosphorylation on tyrosine residues.

Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.

Similarity: Contains 1 protein kinase domain.

ErbB4 reacts with cross-reacts with human and mouse. not yet tested in other species..

OMIM: 600543; gene. [NCBI / EBI]

Products similar to ErbB4 antibody:
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    ErbB4 (ready-to-use), IgG
    ErbB4 [SPM338] (ready-to-use), IgG
    TNFSF12 (tumor necrosis factor (ligand) superfamily. member 12), IgG
    TRPC4, IgG
    ErbB4, IgG
 PRODUCT INTERACTIONS:
 ErbB4 interacts with PSD95 [7E3-1B8], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF R, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [ICR10], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [Cocktail R19/48 (111.6 + 199.12 + F4 + 11E8)], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [199.12], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [2E9], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Acitve EGF Receptor EIA Kit, ELISA_Kits (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Ser1070), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr1092), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Thr678), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Thr693), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr1172), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr1197), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr869), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (phospho-Tyr1110), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-1070), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-1092), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-678), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-693), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-1172), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-1197), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-869), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Ab-1110), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Ser1070) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr1092) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR(Phospho-Tyr1172) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr1197) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Phospho-Tyr869) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (phospho-Tyr1110) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (External Domain), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (Internal Domain), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR pTyr 845, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR (a.a. 1165-1186), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR dpTyr 1173, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR, Activated pTyr 1173, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR pS1047, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR pThr 654, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR, pTyr 1045, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF Receptor (non-ligand binding site), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF Receptor (ligand binding site), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF Receptor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF Receptor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Rabbit anti EGFR (a.a. 1168-1181), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Rabbit anti EGF Receptor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR Human Sf9, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR Human, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR Human Sf9, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Anti-Epidermal Growth Factor Receptor (EGFR) pY1197, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Anti-Epidermal Growth Factor Receptor (EGFR) pY1197, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [ICR10] (FITC), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [29.1], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y1148, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [SP9] (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [EGFR1], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF R, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y1173, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y1068, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y845, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [F4], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [ICR61], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [R19/48], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [H9B4], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [F4], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y1086, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR phospho Y992, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGFR [F4] (FITC), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with EGF R, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with epidermal growth factor receptor isoform a precursor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with epidermal growth factor receptor isoform a precursor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with epidermal growth factor receptor isoform a precursor, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with c-ErbB2 (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with c-ErbB2 [3B5], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB2 [CB11] (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr877), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr1221/Tyr1222), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr1248), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Ab-877), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Ab-1221/1222), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Ab-1248), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr877) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr1221/Tyr1222) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER2 (Phospho-Tyr1248) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with HER-2/Neu (c-erbB-2), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Human HER2/neu,, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with c-erbB2 Human, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB-2 Human, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB2 (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB2, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB2 phospho Y1248, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB2 [ICR55], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with CD340, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3 (ready-to-use), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3 [RTJ1], IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Rabbit anti HER3 (a.a. 1283-1323), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3 Human, Protein (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Anti-HER3, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with ErbB3, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Glutamate [NMDA] receptor subunit zeta 1, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with Rabbit Anti-NMDA receptor NR2A, IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with NMDAR1 (Phospho-Ser896), IgG (GenWay Catalog #: 18-272-196265).
 ErbB4 interacts with NMDAR1 (Phospho-Ser896) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-196265).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ErbB4 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ErbB4 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ErbB4 antibody, all related information, articles, resources about ErbB4 antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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