Pyruvate Kinase antibody, Pyruvate Kinase Antibody, Goat Polyclonal Antibody

Alphabetical Listing of Primary Antibodies:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Alphabetical Listing of Proteins:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Peptides \| Secondary Antibodies \| ELISA Kits

Pyruvate Kinase Antibody, Goat Polyclonal Antibody

Catalog Number: 18-272-197501

Buy Pyruvate Kinase antibody -

Volume:

Related Product Names:

- Pyruvate Kinase antibody; Pyruvate Kinase; PK2; PK3; PKM; Pyruvate Kinase
- Goat polyclonal to Pyruvate Kinase; Pyruvate kinase isozymes M1/M2

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: Pyruvate Kinase	Gene Name Synonym: PK2; PK3; PKM
Gi #: N/A	NCBI Acc #: NP_002645.3	Swiss Prot Acc #: P14618
Length (aa): N/A	Mol. Weight (Da): 57937	Chrom Location: N/A

Isotype: IgG

Immunogen: Pyruvate Kinase from rabbit muscle

Antigen Species: Rabbit

Specificity: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Pyruvate Kinase from rabbit muscle.

Target: Pyruvate Kinase

Localization: Cytoplasmic

Concentration: 10 mg/ml

Purification Note: From polyclonal serum

Storage Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, containing 0.01% sodium azide

Application Note: Suggested working dilution(s):Against 1.0 ug of Pyruvate Kinase from rabbit muscle in standard sandwich ELISA - 1:1,000 to 1:7,000 Not yet tested in other applications. Optimal titers for other applications should be determined by the researcher.

Cellular Localization: Cytoplasmic

Source/Host: Goat

Purity/Purification: IgG fraction

Clonality: Polyclonal

Crossreactivity: Cross-reacts with Rabbit, not yet tested in other species.

Format: Liquid

Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for PYRUVATE KINASE ANTIBODY:

Conjugation, ELISA, IP, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

PYRUVATE KINASE ANTIBODY TARGET DESCRIPTION:

Synonym Names for Pyruvate Kinase antibody: Pyruvate Kinase; PK2; PK3; PKM; Goat polyclonal to Pyruvate Kinase; Pyruvate kinase isozymes M1/M2

Function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP.

Catalytic Activity: ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor: Magnesium.

Cofactor: Potassium.

Enzyme Regulation: Isoform M2 is allosterically activated by D-fructose 1,6-biphosphate (FBP). Inhibited by oxalate.

Biophysicochemical Properties:

Pathway: Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit: Homotetramer. Interacts with HERC1.

Ptm: Phosphorylated upon DNA damage, probably by ATM or ATR.

Miscellaneous: There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. L type is major isozyme in the liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells.

Similarity: Belongs to the pyruvate kinase family.

Pyruvate Kinase reacts with cross-reacts with rabbit, not yet tested in other species..

OMIM: 179050; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Carbon fixation 00710
KEGG pathway: Glycolysis / Gluconeogenesis 00010
KEGG pathway: Insulin signaling pathway 04910
KEGG pathway: Purine metabolism 00230
KEGG pathway: Pyruvate metabolism 00620
KEGG pathway: Type II diabetes mellitus 04930
Reactome Event:Metabolism of carbohydrates 71387

Products similar to Pyruvate Kinase antibody:

IgG

PRKCN, IgG

RIPK3 (receptor-interacting serine-threonine kinase 3), IgG

AMPK1/AMPK2 (Ab-485/491), IgG

Tumour Type M2 Pyruvate Kinase (M2PK), IgG

Mitogen-activated protein kinase 1, IgG

Native_Protein

PYRUVATE KINASE, Native_Protein

p44/42 MAP Kinase (Phospho-Tyr204) Antibody Blocking Peptide, Peptide

p44/42 MAP Kinase Phospho-Thr202) Antibody Blocking Peptide, Peptide

ERK1/MAPK3 Human, Protein

UPK3 Human, Protein

PRODUCT INTERACTIONS:

Pyruvate Kinase interacts with beta 1 Arrestin phospho S412, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with NDRG1 (N-myc downstream regulated gene 1), IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with c-Raf phospho Y340, Y341, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with c-Raf phospho S338, Y340, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with c-Raf phospho S259, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with RAF1, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with RAF1 [410], IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with Raf1 (Phospho-Ser259), IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with Raf1 (Ab-259), IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with Raf1 (Phospho-Ser259) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with Raf-1, N-terminal, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with Anti-Raf-1 pS239, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with c-Raf phospho S43 antibody, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with RAF-1, IgG (GenWay Catalog #: 18-272-197501).

Pyruvate Kinase interacts with c-Raf phospho S621, IgG (GenWay Catalog #: 18-272-197501).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: Pyruvate Kinase antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of Pyruvate Kinase antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Pyruvate Kinase antibody, all related information, articles, resources about Pyruvate Kinase antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.

Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays.



GenWay Biotech, Inc. 6777 Nancy Ridge Drive, San Diego, CA 92121 Tel: (858)458-0866 Fax: (858)458-0833 Email: sales@genwaybio.com www.genwaybio.com ©1998 - 2010 GenWay Biotech, Inc. - All Rights Reserved