CXCL12 antibody, CXCL12 Antibody, Rabbit Polyclonal Antibody

Alphabetical Listing of Primary Antibodies:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Alphabetical Listing of Proteins:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Peptides \| Secondary Antibodies \| ELISA Kits

CXCL12 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-272-198013

Buy CXCL12 antibody -

Size:

Related Product Names:

- CXCL12 antibody; CXCL12; Chemokine (C X C motif) ligand 12 antibodyChemokine (CXC motif) ligand 12 antibodyCXCL 12 antibodyCXCL12 antibodyhIRH antibo; CXCL12
- Rabbit polyclonal to CXCL12; Stromal cell-derived factor 1

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: CXCL12	Gene Name Synonym: Chemokine (C X C motif) ligand 12 antibodyChemokine (CXC motif) ligand 12 antibodyCXCL 12 antibodyCXCL12 antibodyhIRH antibo
Gi #: N/A	NCBI Acc #: NP_000600.1	Swiss Prot Acc #: P48061
Length (aa): N/A	Mol. Weight (Da): 10666	Chrom Location: N/A

Isotype: IgG

Immunogen: Recombinant protein - mouse CXCL12

Antigen Species: Rat

Specificity: CXCL12 in transfected cells

Target: CXCL12

Concentration: 1 mg/ml

Purification Note: From polyclonal serum

Storage Buffer: Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide

Application Note: For WB: Use at a dilution of 1:1,000. For IP: Use at a dilution of 1:300 - 1:500. For IHC: Use at a dilution of 1:100 - 1:500. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Source/Host: Rabbit

Purity/Purification: Protein A affinity purified

Clonality: Polyclonal

Crossreactivity: Rat and Mouse - Not yet tested in other species

Format: Liquid

Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for CXCL12 ANTIBODY:

IHC, IP, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

CXCL12 ANTIBODY TARGET DESCRIPTION:

Synonym Names for CXCL12 antibody: CXCL12; Chemokine (C X C motif) ligand 12 antibodyChemokine (CXC motif) ligand 12 antibodyCXCL 12 antibodyCXCL12 antibodyhIRH antibo; Rabbit polyclonal to CXCL12; Stromal cell-derived factor 1

CXCL12, Stromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).

Function: Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites.

Subcellular Location: Secreted.

Ptm: Processed forms SDF-1-beta(3-72) and SDF-1-alpha(3-67) are produced after secretion by proteolytic cleavage of isoforms Beta and Alpha, respectively. The N-terminal processing is probably achieved by DPP4. Isoform Alpha is first cleaved at the C-terminus to yield a SDF-1-alpha(1-67) intermediate before being processsed at the N-terminus. The C-terminal processing of isoform Alpha is reduced by binding to heparin and, probably, cell surface proteoglycans.

Similarity: Belongs to the intercrine alpha (chemokine CxC) family.

CXCL12 reacts with rat and mouse - not yet tested in other species.

OMIM: 600835; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Axon guidance 04360
KEGG pathway: Cytokine-cytokine receptor interaction 04060
KEGG pathway: Leukocyte transendothelial migration 04670

Products similar to CXCL12 antibody:

IgG

CXCL12 (chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)), IgG

SDF-1 BETA, IgG

SDF-1 ALPHA, IgG

SDF1, IgG

SDF-1 ALPHA, IgG

Protein

SDF-1a Mouse, Protein

Human SDF-1b,, Protein

SDF-1 BETA, Protein

SDF-1b Human, Protein

SDF-1a,, Protein

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: CXCL12 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of CXCL12 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CXCL12 antibody, all related information, articles, resources about CXCL12 antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.

Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays.



GenWay Biotech, Inc. 6777 Nancy Ridge Drive, San Diego, CA 92121 Tel: (858)458-0866 Fax: (858)458-0833 Email: sales@genwaybio.com www.genwaybio.com ©1998 - 2010 GenWay Biotech, Inc. - All Rights Reserved