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DNA polymerase delta Antibody, Mouse Polyclonal Antibody Printer Friendly Datasheet
Catalog Number: 18-272-198039
Buy DNA polymerase delta antibody - Volume:   
  Related Product Names:
- DNA polymerase delta antibody; DNA polymerase delta; DNA pol delta, DNA polymerase d; DNA polymerase delta
- Mouse polyclonal antiserum to human DNA polymerase delta; 5424; POLD1; 174761; P28340; POLD;; 5424; POLD1; 174761; P28340; POLD;
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: DNA polymerase delta  Gene Name Synonym: DNA pol delta, DNA polymerase d

 Gi #: N/A

 NCBI Acc #: NP_002682.2

 Swiss Prot Acc #: P28340

 Length (aa): N/A

 Mol. Weight (Da): 123631

 Chrom Location: N/A
 Isotype: IgG

 Immunogen: Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

 Antigen Species: Human

 Positive Control: HeLa

 Target: DNA polymerase delta

 Purification Note: From polyclonal serum.

 Application Note: For WB: Use at a dilution of 1:500. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.

 Expression system: pQE-30

 Source/Host: Mouse

 Purity/Purification: Unpurified

 Clonality: Polyclonal

 Crossreactivity: Human - Not yet tested in other species

 Format: Liquid

 Storage: Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for DNA POLYMERASE DELTA ANTIBODY:
 WB: Tested
 TESTING: (secondary reagents and protocols )
 Not Available
 DNA POLYMERASE DELTA ANTIBODY TARGET DESCRIPTION:
Synonym Names for DNA polymerase delta antibody: DNA polymerase delta; DNA pol delta, DNA polymerase d; Mouse polyclonal antiserum to human DNA polymerase delta; 5424; POLD1; 174761; P28340; POLD;; 5424; POLD1; 174761; P28340; POLD;

DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3' to 5' exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex

Function: Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex.

Catalytic Activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Subunit: Heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. The 125 kDa subunit contains the polymerase active site and most likely the active site for the 3'-5' exonuclease activity. Interacts with WRNIP1. Interacts with POLD4 and PCNA.

Subcellular Location: Nucleus.

Miscellaneous: In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.

Similarity: Belongs to the DNA polymerase type-B family.

DNA polymerase delta reacts with human - not yet tested in other species .

OMIM: 174761; gene. [NCBI / EBI]

Pathways:
KEGG pathway: DNA polymerase 03030
KEGG pathway: Purine metabolism 00230
KEGG pathway: Pyrimidine metabolism 00240
Reactome Event:Cell Cycle, Mitotic 69278
Reactome Event:DNA Repair 73894
Reactome Event:DNA Replication 69306
Reactome Event:Telomere Maintenance 157579

Products similar to DNA polymerase delta antibody:
 IgG
    PCNA, IgG
    DNA polymerase delta [607], IgG
    DNA polymerase delta [6196], IgG
    PCNA [PC10] (ready-to-use), IgG
    PCNA (ready-to-use), IgG
 PRODUCT INTERACTIONS:
 DNA polymerase delta interacts with c-Abl phospho Y245, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl (Phospho-Tyr412), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl (Ab-412), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl (Phospho-Tyr412) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Herpes Type 6 p150, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl (ready-to-use), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl [19-110], IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl [ABL-148], IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl phospho Y412, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with c-Abl, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with FYN, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with FYN [FYN-01], IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Fyn-p59 Human, Protein (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with FYN, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Growth factor receptor-bound protein 2, Protein (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Grb2, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with GRB2 [R11], IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with GRB2 [R13], IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Grb2, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Grb2, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Grb2, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Protein tyrosine phosphatase type IVA protein 3, Protein (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC, Protein (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC phospho Y529, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src (Phospho-Tyr418), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src (Phospho-Tyr529), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src (Ab-418), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src (Ab-529), IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src(Phospho-Tyr418) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src (Phospho-Tyr529) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with Src Mouse, Protein (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC, IgG (GenWay Catalog #: 18-272-198039).
 DNA polymerase delta interacts with SRC phospho Y418, IgG (GenWay Catalog #: 18-272-198039).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Precautions: DNA polymerase delta antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of DNA polymerase delta antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about DNA polymerase delta antibody, all related information, articles, resources about DNA polymerase delta antibody are being stored on our online database. Let us know if you have questions regarding this product.

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