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| E2F5 Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-272-198250 |
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| Related Product Names:
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E2F5 antibody; E2F5; 1875; E2F5; 600967; Q15329; E2F-5;; E2F5
- Rabbit Polyclonal to E2F - 5 Transcription Factor; 1875; E2F5; 600967; Q15329; E2F-5;; Transcription factor E2F5 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: E2F5 |
Gene Name Synonym: 1875; E2F5; 600967; Q15329; E2F-5; |
Gi #:
N/A |
NCBI Acc #:
NP_001077057.1 |
Swiss Prot Acc #:
Q15329 |
Length (aa): N/A |
Mol. Weight (Da): 37610 |
Chrom Location: N/A |
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 Immunogen: Synthetic peptide from the N-terminus of human E2F-5 protein
Antigen Species: Human
Positive Control: MCF-7, NIH/3T3 Cells
Target: E2F5
Concentration: 1 mg/ml
Storage Buffer: 10mM Phosphate-buffered saline containing 0.2% BSA and 0.1% sodium azide
Application Note: For WB: Use at a dilution of 1:1,000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Source/Host: Rabbit
Purity/Purification: Protein A affinity purified
Clonality: Polyclonal
Crossreactivity: Human, Mouse, and Rat - Not yet tested in other species
Format: Liquid
Storage: Keep as concentrated solution, aliquot and store at 4C. Do not freeze.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for E2F5 ANTIBODY: |
| WB: Tested |
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| E2F5 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for E2F5 antibody: E2F5; 1875; E2F5; 600967; Q15329; E2F-5;; Rabbit Polyclonal to E2F - 5 Transcription Factor; 1875; E2F5; 600967; Q15329; E2F-5;; Transcription factor E2F5
E2F transcription factors are functionally regulated by binding to Rb p110, p107, and p130. E2F family members bind DNA as heterodimers with members of the DP family of polypeptides.
Function: Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation.
Subunit: Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites. Interaction with retinoblastoma protein RB1 or proteins RBL1 and RBL2 inhibits the E2F transactivation domain. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.
Subcellular Location: Nucleus.
Similarity: Belongs to the E2F/DP family.
E2F5 reacts with human, mouse, and rat - not yet tested in other species .
OMIM: 600967; gene. [NCBI / EBI]
Pathways:
KEGG pathway: Cell cycle 04110
KEGG pathway: TGF-beta signaling pathway 04350
Reactome Event:Cell Cycle, Mitotic 69278
Products similar to E2F5 antibody:
IgG
 E2F5 (E2F transcription factor 5. p130-binding), IgG
EIF3S9 (eukaryotic translation initiation factor 3. subunit 9 eta. 116kDa), IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: E2F5 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of E2F5 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about E2F5 antibody, all related information, articles, resources about E2F5 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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