GSK3 antibody, GSK3-beta (Phospho-Ser9) Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

GSK3-beta (Phospho-Ser9) Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-785-210181

Buy GSK3 antibody -

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Related Product Names:

- GSK3 antibody; GSK3; GSK3-beta (Phospho-Ser9)
- EC 2.7.11.26; GSK-3 beta; Glycogen synthase kinase-3 beta

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: GSK3	Gene Name Synonym: N/A
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: P49841
Length (aa): N/A	Mol. Weight (Da): 46744	Chrom Location: N/A

Binding Site: Ser9

WB Dilution: 500~1000

IHC Dilution: 50~100

Specificity/Sensitivity: GSK3-beta (phospho-Ser9) antibody detects endogenous levels of GSK3-beta only when phosphorylated at serine 9.

Applications: WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human GSK3-beta around the phosphorylation site of serine 9 (T-T-S^P-F-A).

Source/Host: Rabbit

Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation

Clonality: Polyclonal

Crossreactivity: Human, Mouse, Rat

Format: Rabbit IgG in phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage: 4C for short term (weeks) and -20C for long term. Avoid frequent freeze and thaw.

Stability: 1 year at -20C

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for GSK3 ANTIBODY:

IHC, WB: Tested

TESTING: (secondary reagents and protocols )

Western Blot ( anti-GSK3 )

GSK3 antibody tern B image
GSK3

IHC ( anti-GSK3 )

GSK3 antibody image
GSK3

IF ( anti-GSK3 )

GSK3 antibody image
GSK3

GSK3 ANTIBODY TARGET DESCRIPTION:

Synonym Names for GSK3 antibody: GSK3; EC 2.7.11.26; GSK-3 beta; Glycogen synthase kinase-3 beta

Function: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.

Catalytic Activity: ATP + [tau protein] = ADP + [tau protein] phosphate.

Enzyme Regulation: Inhibited when phosphorylated by AKT1.

Subunit: Monomer (By similarity). Interacts with NIN and CABYR.

Tissue Specificity: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.

Ptm: Phosphorylated by AKT1 and ILK1.

Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

Similarity: Contains 1 protein kinase domain.

GSK3-beta (Phospho-Ser9) reacts with human, mouse, rat.

OMIM: 605004; gene. [NCBI / EBI]

Products similar to GSK3 antibody:

IgG

GSK3A (glycogen synthase kinase 3 alpha), IgG

GSK3 alpha & beta (ready-to-use), IgG

GSK3 alpha & beta, IgG

PRODUCT INTERACTIONS:

GSK3-beta (Phospho-Ser9) interacts with RAC-alpha serine/threonine-protein kinase, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1 Human, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKAkt1/PKBa Human, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with RAC-alpha serine/threonine-protein kinase, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt1 (inactive) HUMAN, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKBa (Akt1), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Phospho-Ser473), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Ab-473), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Phospho-Thr308), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Ab-308), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Phospho-Ser473) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt (Phospho-Thr308) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKB, dephospho-Ser 473, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKB, pS 473, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKB/Akt, C-terminal, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Rabbit anti PKB (AKT) pS473, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Rabbit anti PKB (AKT) pT308, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Rabbit anti PKB (AKT) (460-480), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKB (AKT) (460-480) Peptide, Native_Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKAkt1/PKBa Human, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-AKT (Human/Mouse/Rat /Chicken specific), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-AKT phospho specific pS473, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-AKT phospho specific pT308, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-IL-7 Receptor alpha chain pY449, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT1, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with RAC-beta serine/threonine-protein kinase, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt2 (inactive) HUMAN, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with PKBb (Akt2), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt2 (Phospho-Ser474), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt2 (Ab-474), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Akt2 (Phospho-Ser474) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Rabbit anti PKB beta (AKT2), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-AKT2, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with AKT2, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Gemin 3, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Gemin3, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Gemin 3 [12H12], IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Glyco.Synthase Kin.3b, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Anti-Human Muscle Glycogen Synthase pS640, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Glycogen synthase phospho S640, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with SF3B1 (splicing factor 3b. subunit 1. 155kDa), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with Human anti Human RNP Antigen, IgG (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with U1snRNP-68 Human, Protein (GenWay Catalog #: 18-785-210181).

GSK3-beta (Phospho-Ser9) interacts with SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG (GenWay Catalog #: 18-785-210181).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for GSK3 ANTIBODY:

Background references for antibody target are not specific to GenWay products

[1] Stambolic V., Woodgett J.R.
     Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.
[2] Rhoads A.R., Karkera J.D., Detera-Wadleigh S.D.
     Radiation hybrid mapping of genes in the lithium-sensitive wnt signaling pathway.
[3] Lau K.F., Miller C.C.J., Anderton B.H., Shaw P.C.
     Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter.
[4] Delcommenne M., Tan C., Gray V., Rue L., Woodgett J.R., Dedhar S.
     Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.
[5] Hong Y.-R., Chen C.-H., Chang J.-H., Wang S.-K., Sy W.-D., Chou C.-K., Howng S.-L.
     Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta.
[6] Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J., Li J., Cohn M.A., Cantley L.C., Gygi S.P.
     Large-scale characterization of HeLa cell nuclear phosphoproteins.
[7] Hsu H.-C., Lee Y.-L., Cheng T.-S., Howng S.-L., Chang L.-K., Lu P.-J., Hong Y.-R.
     Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.
[8] Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J., Lauffenburger D.A., White F.M.
     Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.
[9] Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J., et al.
     Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
[10] Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
     Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: GSK3 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of GSK3 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GSK3 antibody, all related information, articles, resources about GSK3 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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