Alphabetical Listing of Primary Antibodies:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Alphabetical Listing of Proteins:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Peptides
|
Secondary Antibodies
|
ELISA Kits
GSK3-beta (Ab-9) Antibody, Rabbit Polyclonal Antibody
Catalog Number: 18-785-210183
Buy GSK3 antibody -
Size:
0.05 mg ($225.00)
0.1 mg ($315.00)
Related Product Names:
- GSK3 antibody; GSK3; GSK3-beta (Ab-9)
- EC 2.7.11.26; GSK-3 beta; Glycogen synthase kinase-3 beta
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
GSK3
Gene Name Synonym:
N/A
Gi #:
N/A
NCBI Acc #:
N/A
Swiss Prot Acc #:
P49841
Length (aa):
N/A
Mol. Weight (Da):
46744
Chrom Location:
N/A
Binding Site:
around Ser9
WB Dilution:
500~1000
IHC Dilution:
50~100
Form of Antibody:
Rabbit IgG in phosphate buffered saline (without Mg
2+
and Ca
2+
), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from human GSK3-beta around the phosphorylation site of serine 9 (T-T-S
P
-F-A).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:
GSK3-beta (Ab-9) antibody detects endogenous levels of total GSK3-beta protein, this antibody may cross-react with the GSK-3-alpha due to high sequence homology.
Applications:
WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200
Source/Host:
Rabbit
Purity/Purification:
Affinity Purified
Clonality:
Polyclonal
Crossreactivity:
Human, Mouse, Rat
Format:
In PBS, 0.02% sodium azide and 50% glycerol.
Storage:
Store at -20C / 1year. Avoid frequent freeze and thaw.
Stability:
1 year at -20C
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for GSK3 ANTIBODY:
IHC, WB: Tested
TESTING: (
secondary reagents
and
protocols
)
Western Blot: Western blot analysis of extracts from 293 cells treated with 10% serum (30min), using GSK3? (Ab-9) antibody ( anti-GSK3 )
GSK3 antibody tern Blot image
IHC: Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using GSK3? (Ab-9) antibody ( anti-GSK3 )
GSK3 antibody image
IF ( anti-GSK3 )
GSK3 antibody image
GSK3 ANTIBODY TARGET DESCRIPTION:
Synonym Names for GSK3 antibody:
GSK3; EC 2.7.11.26; GSK-3 beta; Glycogen synthase kinase-3 beta
Function:
Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.
Catalytic Activity:
ATP + [tau protein] = ADP + [tau protein] phosphate.
Enzyme Regulation:
Inhibited when phosphorylated by AKT1.
Subunit:
Monomer (By similarity). Interacts with NIN and CABYR.
Tissue Specificity:
Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.
Ptm:
Phosphorylated by AKT1 and ILK1.
Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Similarity:
Contains 1 protein kinase domain.
GSK3-beta (Ab-9) reacts with human, mouse, rat.
OMIM:
605004; gene. [
NCBI
/
EBI
]
Products similar to GSK3 antibody:
IgG
GSK3 alpha & beta, IgG
GSK3A (glycogen synthase kinase 3 alpha), IgG
GSK3 alpha & beta (ready-to-use), IgG
PRODUCT INTERACTIONS:
GSK3-beta (Ab-9)
interacts
with
RAC-alpha serine/threonine-protein kinase, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1 Human, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKAkt1/PKBa Human, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
RAC-alpha serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
RAC-alpha serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt1 (inactive) HUMAN, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKBa (Akt1), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Phospho-Ser473), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Ab-473), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Phospho-Thr308), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Ab-308), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Phospho-Ser473) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt (Phospho-Thr308) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKB, dephospho-Ser 473, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKB, pS 473, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKB/Akt, C-terminal, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Rabbit anti PKB (AKT) pS473, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Rabbit anti PKB (AKT) pT308, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Rabbit anti PKB (AKT) (460-480), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKB (AKT) (460-480) Peptide, Native_Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKAkt1/PKBa Human, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-AKT (Human/Mouse/Rat /Chicken specific), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-AKT phospho specific pS473, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-AKT phospho specific pT308, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-IL-7 Receptor alpha chain pY449, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
RAC-beta serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt2 (inactive) HUMAN, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
PKBb (Akt2), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt2 (Phospho-Ser474), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt2 (Ab-474), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Akt2 (Phospho-Ser474) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Rabbit anti PKB beta (AKT2), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-AKT2, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
AKT2, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Gemin 3, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Gemin3, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Gemin 3 [12H12], IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Glyco.Synthase Kin.3b, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Anti-Human Muscle Glycogen Synthase pS640, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Glycogen synthase phospho S640, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
SF3B1 (splicing factor 3b. subunit 1. 155kDa), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
Human anti Human RNP Antigen, IgG
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
U1snRNP-68 Human, Protein
(GenWay Catalog #: 18-785-210183)
.
GSK3-beta (Ab-9)
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-785-210183)
.
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
BACKGROUND REFERENCES for GSK3 ANTIBODY:
Background references for antibody target are not specific to GenWay products
[1]
Stambolic V., Woodgett J.R.
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.
[2]
Rhoads A.R., Karkera J.D., Detera-Wadleigh S.D.
Radiation hybrid mapping of genes in the lithium-sensitive wnt signaling pathway.
[3]
Lau K.F., Miller C.C.J., Anderton B.H., Shaw P.C.
Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter.
[4]
Delcommenne M., Tan C., Gray V., Rue L., Woodgett J.R., Dedhar S.
Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase.
[5]
Hong Y.-R., Chen C.-H., Chang J.-H., Wang S.-K., Sy W.-D., Chou C.-K., Howng S.-L.
Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3beta.
[6]
Beausoleil S.A., Jedrychowski M., Schwartz D., Elias J.E., Villen J., Li J., Cohn M.A., Cantley L.C., Gygi S.P.
Large-scale characterization of HeLa cell nuclear phosphoproteins.
[7]
Hsu H.-C., Lee Y.-L., Cheng T.-S., Howng S.-L., Chang L.-K., Lu P.-J., Hong Y.-R.
Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain.
[8]
Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J., Lauffenburger D.A., White F.M.
Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.
[9]
Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J., et al.
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
[10]
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
GSK3 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of GSK3 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GSK3 antibody, all related information, articles, resources about GSK3 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
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