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| VEGFR2 (Phospho-Tyr1214) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-785-210473 |
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| Related Product Names:
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VEGFR2 antibody; VEGFR2; FLK1; VEGFR2 (Phospho-Tyr1214)
- EC 2.7.10.1; VEGFR-2; Kinase insert domain receptor; Protein-tyrosine kinase receptor Flk-1; CD309 antigen; Vascular endothelial growth factor receptor 2 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: VEGFR2 |
Gene Name Synonym: FLK1 |
Gi #:
N/A |
NCBI Acc #:
N/A |
Swiss Prot Acc #:
P35968 |
Length (aa): N/A |
Mol. Weight (Da): 151527 |
Chrom Location: N/A |
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 Binding Site: Tyr1214
WB Dilution: 500~1000
IHC Dilution: 50~100
Source/Host: Rabbit
Purity/Purification: Affinity Purified
Clonality: Polyclonal
Crossreactivity: Human, Mouse
Format: In PBS, 0.02% sodium azide and 50% glycerol.
Storage: 4C for short term (weeks) and -20C for long term. Avoid frequent freeze and thaw.
Stability: 1 year at -20C
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for VEGFR2 ANTIBODY: |
| IHC: Tested |
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| VEGFR2 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for VEGFR2 antibody: VEGFR2; FLK1; EC 2.7.10.1; VEGFR-2; Kinase insert domain receptor; Protein-tyrosine kinase receptor Flk-1; CD309 antigen; Vascular endothelial growth factor receptor 2
Function: Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Catalytic Activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat.
Subcellular Location: Membrane; Single-pass type I membrane protein.
Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Similarity: Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Similarity: Contains 1 protein kinase domain.
VEGFR2 (Phospho-Tyr1214) reacts with human, mouse.
OMIM: 191306; gene. [NCBI / EBI]
Pathways:
KEGG pathway: Cytokine-cytokine receptor interaction 04060
KEGG pathway: Focal adhesion 04510
KEGG pathway: VEGF signaling pathway 04370
Products similar to VEGFR2 antibody:
IgG
 VEGFR2 (Ab-1214), IgG
VEGFR2 (Phospho-Tyr1175), IgG
VEGF receptor 2, IgG
VEGFR2, IgG
VEGF receptor 2 phospho Y1054, IgG
Peptide
VEGFR2 (Phospho-Tyr1214) Antibody Blocking Peptide, Peptide
VEGFR2 (Phospho-Tyr1175) Antibody Blocking Peptide, Peptide
VEGFR2 (Phospho-Tyr951) Antibody Blocking Peptide, Peptide
VEGFR-2 Human, Protein
VEGFR-2 Fc Human, Protein
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| PRODUCT INTERACTIONS: |
VEGFR2 (Phospho-Tyr1214) interacts with VEGF receptor 3, IgG (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with VEGFR-3 Human, Protein (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with VEGFR-3 Fc Human, Protein (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with FLT4, IgG (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with VEGF receptor 3 (ready-to-use), IgG (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with VEGF receptor 3, IgG (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with Neuropilin 1, IgG (GenWay Catalog #: 18-785-210473).
VEGFR2 (Phospho-Tyr1214) interacts with Neuropilin-1, IgG (GenWay Catalog #: 18-785-210473).
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for VEGFR2 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
[1] Yin L.Y., Wu Y., Patterson C.
Full length human KDR/flk-1 sequence.
[2] Yu Y., Whitney R.G., Sato J.D.
Coding region for human VEGF receptor KDR (VEGFR-2).
[3] Terman B.I., Carrion M.E., Kovacs E., Rasmussen B.A., Eddy R.L., Shows T.B.
Identification of a new endothelial cell growth factor receptor tyrosine kinase.
[4] Patterson C., Perrella M.A., Hsieh C.-M., Yoshizumi M., Lee M.-E., Harber E.
Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor.
[5] Terman B.I., Dougher-Vermazen M., Carrion M.E., Dimitrov D., Armellino D.C., Gospodarowicz D., Boehlen P.
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor.
[6] Mitola S., Soldi R., Zanon I., Barra L., Gutierrez M.I., Berkhout B., Giacca M., Bussolino F.
Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells.
[7] Holmqvist K., Cross M.J., Rolny C., Haegerkvist R., Rahimi N., Matsumoto T., Claesson-Welsh L., Welsh M.
The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: VEGFR2 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of VEGFR2 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about VEGFR2 antibody, all related information, articles, resources about VEGFR2 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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