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| b-Catenin (CTNNB1) Dephospho Antibody, Sheep Polyclonal Antibody |
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| Catalog Number: 18-006-222018 |
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| Related Product Names:
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b-Catenin (CTNNB1) Dephospho antibody; b-Catenin (CTNNB1) Dephospho |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: N/A |
Gene Name Synonym: N/A |
Gi #:
N/A |
NCBI Acc #:
N/A |
Swiss Prot Acc #:
P35222 |
Length (aa): N/A |
Mol. Weight (Da): 92 kDa |
Chrom Location: N/A |
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 GenWay Biotech supplies human recombinant proteins expressed from human cells (hcx). This protein is expressed from modified human 293 cells, which has the cellular machinery necessary to attach human post-translational modifications (PTMs) to itself. As such, this protein is different from its recombinant form expressed from other species. GenWay utilizes conventional chromatography purification techniques to purify the proteins. No tag-based affinity chromatography techniques are used for ligands. Each protein has purity greater than 95% by silver stain, with most proteins >97% pure. |
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Immunogen: CQSYLDSGIHSGATTTAPSL
MW: 92 kDa
App Notes: For Western blot analysis, block membrane with 5 % w/v milk, 1x TBS and 0.1% Tween-20 (TBST) for 30 min at room temperature and incubate with diluted antibody (in 1 % w/v milk, TBST) at 4 °C overnight with gentle rocking.
Recommended Ab Dilution: Western blotting 2 ug/ml
Source/Host: Sheep
Purity/Purification: Affinity purified sheep polyclonal antibody
Clonality: Polyclonal
Crossreactivity: Human, Mouse
Storage: 100 ug supplied as lyophilised protein in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, and 0.05 % sodium azide. Store at 4 C. Reconstitute in 100 ul of sterile water. This product is for in vitro use only
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for B-CATENIN (CTNNB1) DEPHOSPHO ANTIBODY: |
| WB: Tested |
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| TESTING: (secondary reagents and protocols
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Western Blot: Western blot analysis of extracts from HepG2 cells, untreated (lane 1) or treated with GSK3 inhibitor (lane 2). ( anti-b-Catenin (CTNNB1) Dephospho )b-Catenin (CTNNB1) Dephospho antibody Western Blot image
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| B-CATENIN (CTNNB1) DEPHOSPHO ANTIBODY TARGET DESCRIPTION: |
Synonym Names for b-Catenin (CTNNB1) Dephospho antibody: N/A; N/A
This antibody was designed to detect the active form of beta-Catenin as it recognizes the dephosphorylated form of the protein.
Beta-catenin is part of the cadherin cell adhesion complex and central to the Wingless/Wnt signaling pathway, resulting in beta-catenin accumulation and transcriptional activation of specific target genes. In the absence of Wnt signaling, APC, beta-catenin, and axin are phosphorylated by GSK-3, leading to ubiquitination of beta-catenin and its degradation by the proteasome. Thus, at steady state in the absence of Wnt signaling, b-catenin is rapidly degraded in the cytoplasm. Nuclear levels of bcatenin are kept low by APC and axin interactions, both of which have a nuclear export activity that shuttles beta-catenin back to the cytoplasm.
b-Catenin (CTNNB1) Dephospho reacts with human, mouse.
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: b-Catenin (CTNNB1) Dephospho antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of b-Catenin (CTNNB1) Dephospho antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about b-Catenin (CTNNB1) Dephospho antibody, all related information, articles, resources about b-Catenin (CTNNB1) Dephospho antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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