FAS antibody, Fas (Intracell. Frag.) Antibody, Mouse Monoclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Fas (Intracell. Frag.) Antibody, Mouse Monoclonal Antibody

Catalog Number: 20-511-240277

Buy FAS antibody -

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Related Product Names:

- FAS antibody; FAS; APT1; FAS1; TNFRSF6; Fas (Intracell. Frag.)
- MAb to Fas (Intracell. Frag.); FASLG receptor; Apoptosis-mediating surface antigen FAS; Apo-1 antigen; CD95 antigen; Tumor necrosis factor receptor superfamily member 6

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: FAS	Gene Name Synonym: APT1; FAS1; TNFRSF6
Gi #: N/A	NCBI Acc #: N/A	Swiss Prot Acc #: P25445
Length (aa): N/A	Mol. Weight (Da): 37732	Chrom Location: N/A

Isotype: IgG1

Clone: GH-9

Host Animal: Mouse

Specificity: Fas (Intracellular Fragment)

Type of Product: Monoclonal Antibodies to Apoptosis and Signal Transduction Reagents

Concentration: 1mg/ml

Preservatives: NaN3

Buffer: PBS, pH 7.2

Applications Notes : Suitable for use in Immunoprecipitation (2-5ug/106 cells), Western blot (1:1000) and ELISA (1:1000). Not tested in IHC. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Source/Host: Mouse

Purity/Purification: Protein A chromatography

Clonality: Monoclonal

Format: Purified, Liquid

Storage: Short term (up to 2 months) store at 2-8 C. Long term, aliquot and store at -20 C. Avoid multiple freeze/thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for FAS ANTIBODY:

ELISA, IP , WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

FAS ANTIBODY TARGET DESCRIPTION:

Synonym Names for FAS antibody: FAS; APT1; FAS1; TNFRSF6; MAb to Fas (Intracell. Frag.); FASLG receptor; Apoptosis-mediating surface antigen FAS; Apo-1 antigen; CD95 antigen; Tumor necrosis factor receptor superfamily member 6

MAb to Fas (Intracell. Frag.). Monoclonal Antibody to Fas (Intracellular Fragment)

Function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Subunit: Binds DAXX. Interacts with HIPK3. Part of a complex containing HIPK3 and FADD (By similarity). Binds RIPK1 and FAIM2. Interacts with BRE and FEM1B.

Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein.

Subcellular Location: Isoform 2: Secreted.

Subcellular Location: Isoform 3: Secreted.

Subcellular Location: Isoform 4: Secreted.

Subcellular Location: Isoform 5: Secreted.

Subcellular Location: Isoform 6: Secreted.

Tissue Specificity: Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.

Domain: Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adapter proteins.

Disease: Defects in FAS are the cause of autoimmune lymphoproliferative syndrome type 1A (ALPS1A) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.

Similarity: Contains 1 death domain.

Similarity: Contains 3 TNFR-Cys repeats.

OMIM: 134637; gene. [NCBI / EBI]
601859; phenotype. [NCBI / EBI]

Products similar to FAS antibody:

IgG

FAS [101624], IgG

FAS [Alf2.1], IgG

PTPN13, IgG

CD178, IgG

Protein

Fas-activated serine/threonine kinase, Protein

CD95 Human, Protein

PRODUCT INTERACTIONS:

Fas (Intracell. Frag.) interacts with Calmodulin Human, Protein (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Caspase-8, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Caspase 8 [C502S], IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Rabbit anti Caspase 8 (Middle), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Rabbit anti Caspase 8 (CT), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Caspase 8 (ready-to-use), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Caspase 8, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with DAXX, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with DAXX [DAXX-01], IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with DAXX, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with FADD (Fas (TNFRSF6)-associated via death domain), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with FADD, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with FADD [FD19], IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Phospho-Ser83), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Phospho-Ser966), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Ab-83), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Ab-966), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Phospho-Ser83) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with ASK1 (Phospho-Ser966) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Rabbit anti ASK-1 pS83, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Anti-ASK-1 phospho specific pS83, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Tyrosine-protein phosphatase non-receptor type 13, Protein (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with PTPN13, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with SRC, Protein (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with SRC, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with SRC phospho Y529, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src (Phospho-Tyr418), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src (Phospho-Tyr529), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src (Ab-418), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src (Ab-529), IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src(Phospho-Tyr418) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src (Phospho-Tyr529) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with Src Mouse, Protein (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with SRC, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with SRC phospho Y418, IgG (GenWay Catalog #: 20-511-240277).

Fas (Intracell. Frag.) interacts with YES1 Human, Protein (GenWay Catalog #: 20-511-240277).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: FAS antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of FAS antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about FAS antibody, all related information, articles, resources about FAS antibody are being stored on our online database. Let us know if you have questions regarding this product.

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