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| HBsAg Antibody, Mouse Monoclonal Antibody |
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| Catalog Number: 20-511-241719 |
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| Related Product Names:
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S antibody; S; HBsAg
- MAb to HBsAg; Large surface protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB; Large envelope protein |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: S |
Gene Name Synonym: N/A |
Gi #:
N/A |
NCBI Acc #:
N/A |
Swiss Prot Acc #:
P03145 |
Length (aa): N/A |
Mol. Weight (Da): 36230 |
Chrom Location: N/A |
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 Isotype: IgG1.k
Clone: 090-18511
Host Animal: Mouse
Specificity: Hepatitis B Surface Antigen (HBsAg)
Type of Product: Monoclonal Antibodies to Infectious Agents and Toxins
Concentration: 5.13mg/ml (OD280nm. E0.1% = 1.4)
Preservatives: NaN3
Buffer: 10mM Phosphate. pH 7.4 containing 150mM Sodium chloride
Applications Notes : Suitable for use in ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Source/Host: Mouse
Purity/Purification: >90% pure (SDS-PAGE). Protein A chromatography.
Product is 0.2um filtered.
Clonality: Monoclonal
Format: Purified, Liquid
Storage: Short term (up to 7 days) store at 2-8 C. Long term, aliquot and store at <-40 C. If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used. Avoid repeated freeze/thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for S ANTIBODY: |
| Pr-ELISA: Tested |
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| S ANTIBODY TARGET DESCRIPTION: |
Synonym Names for S antibody: S; MAb to HBsAg; Large surface protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB; Large envelope protein
MAb to HBsAg. Monoclonal Antibody to Hepatitis B Surface Antigen (HBsAg)
Function: The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. It also assume fusion between virion membrane and cellular membrane. In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein (By similarity).
Function: Truncated S protein may be involved in translocation of pre-S domain through the virion membrane.
Subunit: Large internal envelope protein interacts with capsid protein (By similarity).
Subcellular Location: Virion membrane.
Domain: The large envelope protein is synthesized with the pre-S region at the cytosolic side of the endoplasmic reticulum and, hence will be within the virion after budding. Therefore the pre-S region is not N-glycosylated. Later a post-translational translocation of N-terminal pre-S and TM1 domains occur in about 50% of proteins at the virion surface. These molecules change their topology by an unknown mechanism, resulting in exposure of pre-S region at virion surface.
Ptm: Myristoylation contributes importantly to DHBV infectivity. It is most likely required for an early step of the life cycle involving the entry or uncoating of virus particles.
Ptm: Phosphorylated on pre-S domain for about 50% of L proteins, the L chains with internal pre-S region (Li-HBsAg).
Ptm: Isoform S may be cleaved by a cellular protease to produce truncated S protein.
Similarity: Belongs to the avihepadnavirus major surface antigen family.
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: S antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of S antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about S antibody, all related information, articles, resources about S antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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