DRD2 antibody, Rabbit anti D2 Dopamine Recept Antibody, Rabbit Polyclonal Antibody

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Rabbit anti D2 Dopamine Recept Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-511-244163

Buy DRD2 antibody -

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Related Product Names:

- DRD2 antibody; DRD2; Rabbit anti D2 Dopamine Recept
- Rabbit anti D2 Dopamine Recept; Dopamine D2 receptor; D(2) dopamine receptor

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: DRD2	Gene Name Synonym: N/A
Gi #: N/A	NCBI Acc #: NP_000786.1	Swiss Prot Acc #: P14416
Length (aa): N/A	Mol. Weight (Da): 50619	Chrom Location: N/A

Host Animal: Rabbit

Immunogen: D2 (272-282) covalently attached to a carrier protein.

Specificity: Dopamine D2 Receptor (a.a. 272-282)

Specificity: Specific for Dopamine D2 Receptor (a.a. 272-282). Detects two bands at ~48kDa and ~51kDa in Western blot. Cross-reactivity: D2 Dopamine Receptor (272-282) 100% D2S Dopamine Receptor 70% D2L Dopamine Receptor 60% D1 Dopamine Receptor (9-21) 0% D1 Dopamine Receptor 0% D3 Dopamine Receptor (2-10) 0% D3 Dopamine Receptor 0% D4 Dopamine Receptor (176-185) 0% D4 Dopamine Receptor 0% D5 Dopamine Receptor (23-35) 0% D5 Dopamine Receptor 0%

Type of Product: Polyclonal Antibodies for Neuroscience

Concentration: Not determined

Buffer: Not applicable

Applications Notes : Suitable for use in immunocytochemistry (1:5,000), Western blot (1:800) and ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Source/Host: Rabbit

Clonality: Polyclonal

Format: Neat, Lyophilized Reconstitute with 0.1ml of PBS which contains 10mg/ml BSA or with additional buffer for more dilute antisera.

Storage: Lyophilized: Store at 2-8 C (preferably in a dessicator). Reconstituted: Aliquot and store at -20 C.

Shipping: Products may be shipped on ice pack or dry ice.

TESTING: (secondary reagents and protocols )

Not Available

DRD2 ANTIBODY TARGET DESCRIPTION:

Synonym Names for DRD2 antibody: DRD2; Rabbit anti D2 Dopamine Recept; Dopamine D2 receptor; D(2) dopamine receptor

Rabbit anti D2 Dopamine Recept.. Rabbit Antibody to Dopamine D2 Receptor (amino acids 272-282)

Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

Subunit: Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2.

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Polymorphism: Genetic variations in DRD2 may determine the genetic susceptibility to alcoholism [MIM:103780]. Genetic variations in DRD2 might be a protective factor against the development of withdrawal symptoms but might also be a risk factor in a highly burdened subgroup of alcoholics with a paternal and grandpaternal history of alcoholism and might contribute to suicide risk in alcoholics.

Disease: It has been suggested that DRD2 is involved in psychiatric disorders; especially in schizophrenia.

Disease: Defects in DRD2 are associated with myoclonus dystonia (MD) [MIM:159900]; also known as myoclonic dystonia, alcohol-responsive dystonia and dystonia-11 (DYT11). MD is a movement disorder characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.

Similarity: Belongs to the G-protein coupled receptor 1 family [view classification].

OMIM: 103780; phenotype. [NCBI / EBI]
126450; gene. [NCBI / EBI]
159900; phenotype. [NCBI / EBI]
608516; phenotype. [NCBI / EBI]

Pathways:
KEGG pathway: Gap junction 04540
KEGG pathway: Neuroactive ligand-receptor interaction 04080

Products similar to DRD2 antibody:

IgG

D(2) dopamine receptor, IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

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Precautions: DRD2 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of DRD2 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about DRD2 antibody, all related information, articles, resources about DRD2 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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