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Rabbit anti GSK3b pS9 Antibody, Rabbit Polyclonal Antibody Printer Friendly Datasheet
Catalog Number: 18-511-244379
Buy GSK3B antibody - Size:   
  Related Product Names:
- GSK3B antibody; GSK3B; Rabbit anti GSK3b pS9
- Rabbit anti GSK3b pS9; GSK-3 beta; EC 2.7.11.26; Glycogen synthase kinase-3 beta
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: GSK3B  Gene Name Synonym: N/A

 Gi #: N/A

 NCBI Acc #: NP_002084.2

 Swiss Prot Acc #: P49841

 Length (aa): N/A

 Mol. Weight (Da): 46744

 Chrom Location: N/A
 Host Animal: Rabbit

 Immunogen: A synthetic peptide corresponding to a.a. 4-12 of human GSK3 beta. Sequence: RPRTTSFAE

 Specificity: Glycogen Synthase Kinase 3 beta (GSK3b) phosphorylated at Serine 9

 Specificity: Specific for phosphorylated human GSK3B p59 with minimal crossreactivity against non-phosphorylated GSK3B. Shows a strong signal to GSK3b in Western blot at the estimated molecular weight of 49kD. This antibody may show very weak reactivity against GSK3a.

 Type of Product: Polyclonal Antibodies to Apoptosis and Signal Transduction Reagents

 Concentration: Lot specific (OD280nm)

 Preservatives: NaN3

 Buffer: 0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH 7.2

 Applications Notes : Suitable for use in ELISA, Immunoprecipitation and Western blot. Serum starved 293T whole cell lysate is suitable for use as a positive control. Assayed by ELISA against 0.1ug of the immunizing peptide. A dilution range of 1:10,000 to 1:50,000 is recommended for ELISA and 1:1,000 is recommended for Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

 Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

 Source/Host: Rabbit

 Purity/Purification: Immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption against non-phospho peptide and non-specific peptide to remove unwanted reactivities.

 Clonality: Polyclonal

 Format: Affinity Purified, Liquid

 Storage: Aliquot and store at -20 C or below. Avoid multiple freeze/thaw cycles. Prepare working dilution only prior to immediate use.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for GSK3B ANTIBODY:
 ELISA, WB: Tested
 TESTING: (secondary reagents and protocols )
 Not Available
 GSK3B ANTIBODY TARGET DESCRIPTION:
Synonym Names for GSK3B antibody: GSK3B; Rabbit anti GSK3b pS9; GSK-3 beta; EC 2.7.11.26; Glycogen synthase kinase-3 beta

Rabbit anti GSK3b pS9. Rabbit Antibody to Human Glycogen Synthase Kinase 3 beta (GSK3b) phosphorylated at Serine 9

Function: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.

Catalytic Activity: ATP + [tau protein] = ADP + [tau protein] phosphate.

Enzyme Regulation: Inhibited when phosphorylated by AKT1.

Subunit: Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.

Tissue Specificity: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.

Ptm: Phosphorylated by AKT1 and ILK1.

Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

Similarity: Contains 1 protein kinase domain.

OMIM: 605004; gene. [NCBI / EBI]

Pathways:
KEGG pathway: Alzheimer's disease 05010
KEGG pathway: Axon guidance 04360
KEGG pathway: B cell receptor signaling pathway 04662
KEGG pathway: Basal cell carcinoma 05217
KEGG pathway: Cell cycle 04110
KEGG pathway: Colorectal cancer 05210
KEGG pathway: Endometrial cancer 05213
KEGG pathway: ErbB signaling pathway 04012
KEGG pathway: Focal adhesion 04510
KEGG pathway: Hedgehog signaling pathway 04340
KEGG pathway: Insulin signaling pathway 04910
KEGG pathway: Melanogenesis 04916
KEGG pathway: Prostate cancer 05215
KEGG pathway: Wnt signaling pathway 04310
Reactome Event:Signaling by Wnt 195721
Reactome Event:Signalling by NGF 166520

Products similar to GSK3B antibody:
 IgG
    GSK3 alpha & beta (ready-to-use), IgG
    GSK3 alpha & beta, IgG
 PRODUCT INTERACTIONS:
 Rabbit anti GSK3b pS9 interacts with RAC-alpha serine/threonine-protein kinase, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1 Human, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKAkt1/PKBa Human, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with RAC-alpha serine/threonine-protein kinase, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with RAC-alpha serine/threonine-protein kinase, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt1 (inactive) HUMAN, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKBa (Akt1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Phospho-Ser473), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Ab-473), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Phospho-Thr308), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Ab-308), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Phospho-Ser473) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt (Phospho-Thr308) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKB, dephospho-Ser 473, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKB, pS 473, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKB/Akt, C-terminal, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Rabbit anti PKB (AKT) pS473, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Rabbit anti PKB (AKT) pT308, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Rabbit anti PKB (AKT) (460-480), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKB (AKT) (460-480) Peptide, Native_Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKAkt1/PKBa Human, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-AKT (Human/Mouse/Rat /Chicken specific), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-AKT phospho specific pS473, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-AKT phospho specific pT308, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-IL-7 Receptor alpha chain pY449, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT1, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with RAC-beta serine/threonine-protein kinase, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt2 (inactive) HUMAN, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with PKBb (Akt2), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt2 (Phospho-Ser474), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt2 (Ab-474), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Akt2 (Phospho-Ser474) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Rabbit anti PKB beta (AKT2), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-AKT2, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with AKT2, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Gemin 3, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Gemin3, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Gemin 3 [12H12], IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Glyco.Synthase Kin.3b, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Anti-Human Muscle Glycogen Synthase pS640, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Glycogen synthase phospho S640, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SF3B1 (splicing factor 3b. subunit 1. 155kDa), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SMN (Gemin1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SMN (Gemin1), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with Human anti Human RNP Antigen, IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with U1snRNP-68 Human, Protein (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG (GenWay Catalog #: 18-511-244379).
 Rabbit anti GSK3b pS9 interacts with STRAP (serine/threonine kinase receptor associated protein), IgG (GenWay Catalog #: 18-511-244379).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: GSK3B antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of GSK3B antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GSK3B antibody, all related information, articles, resources about GSK3B antibody are being stored on our online database. Let us know if you have questions regarding this product.

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