Alphabetical Listing of Primary Antibodies:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Alphabetical Listing of Proteins:
f
|
0-4
|
5-9
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
X
|
Y
|
Z
|
Peptides
|
Secondary Antibodies
|
ELISA Kits
Rabbit anti GSK3b pS9 Antibody, Rabbit Polyclonal Antibody
Catalog Number: 18-511-244379
Buy GSK3B antibody -
Size:
0.1 mg ($660.00)
Related Product Names:
- GSK3B antibody; GSK3B; Rabbit anti GSK3b pS9
- Rabbit anti GSK3b pS9; GSK-3 beta; EC 2.7.11.26; Glycogen synthase kinase-3 beta
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact
sales@genwaybio.com
.
Gene Name:
GSK3B
Gene Name Synonym:
N/A
Gi #:
N/A
NCBI Acc #:
NP_002084.2
Swiss Prot Acc #:
P49841
Length (aa):
N/A
Mol. Weight (Da):
46744
Chrom Location:
N/A
Host Animal:
Rabbit
Immunogen:
A synthetic peptide corresponding to a.a. 4-12 of human GSK3 beta. Sequence: RPRTTSFAE
Specificity:
Glycogen Synthase Kinase 3 beta (GSK3b) phosphorylated at Serine 9
Specificity:
Specific for phosphorylated human GSK3B p59 with minimal crossreactivity against non-phosphorylated GSK3B. Shows a strong signal to GSK3b in Western blot at the estimated molecular weight of 49kD. This antibody may show very weak reactivity against GSK3a.
Type of Product:
Polyclonal Antibodies to Apoptosis and Signal Transduction Reagents
Concentration:
Lot specific (OD280nm)
Preservatives:
NaN3
Buffer:
0.02M Potassium Phosphate, 0.15M Sodium Chloride, pH 7.2
Applications Notes :
Suitable for use in ELISA, Immunoprecipitation and Western blot. Serum starved 293T whole cell lysate is suitable for use as a positive control. Assayed by ELISA against 0.1ug of the immunizing peptide. A dilution range of 1:10,000 to 1:50,000 is recommended for ELISA and 1:1,000 is recommended for Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Warning:
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Source/Host:
Rabbit
Purity/Purification:
Immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption against non-phospho peptide and non-specific peptide to remove unwanted reactivities.
Clonality:
Polyclonal
Format:
Affinity Purified, Liquid
Storage:
Aliquot and store at -20 C or below. Avoid multiple freeze/thaw cycles. Prepare working dilution only prior to immediate use.
Shipping:
Products may be shipped on ice pack or dry ice.
APPLICATIONS for GSK3B ANTIBODY:
ELISA, WB: Tested
TESTING: (
secondary reagents
and
protocols
)
Not Available
GSK3B ANTIBODY TARGET DESCRIPTION:
Synonym Names for GSK3B antibody:
GSK3B; Rabbit anti GSK3b pS9; GSK-3 beta; EC 2.7.11.26; Glycogen synthase kinase-3 beta
Rabbit anti GSK3b pS9. Rabbit Antibody to Human Glycogen Synthase Kinase 3 beta (GSK3b) phosphorylated at Serine 9
Function:
Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin.
Catalytic Activity:
ATP + [tau protein] = ADP + [tau protein] phosphate.
Enzyme Regulation:
Inhibited when phosphorylated by AKT1.
Subunit:
Monomer (By similarity). Interacts with CABYR, MUC1, NIN and PRUNE.
Tissue Specificity:
Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.
Ptm:
Phosphorylated by AKT1 and ILK1.
Similarity:
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Similarity:
Contains 1 protein kinase domain.
OMIM:
605004; gene. [
NCBI
/
EBI
]
Pathways:
KEGG pathway: Alzheimer's disease
05010
KEGG pathway: Axon guidance
04360
KEGG pathway: B cell receptor signaling pathway
04662
KEGG pathway: Basal cell carcinoma
05217
KEGG pathway: Cell cycle
04110
KEGG pathway: Colorectal cancer
05210
KEGG pathway: Endometrial cancer
05213
KEGG pathway: ErbB signaling pathway
04012
KEGG pathway:
Focal adhesion
04510
KEGG pathway: Hedgehog signaling pathway
04340
KEGG pathway: Insulin signaling pathway
04910
KEGG pathway: Melanogenesis
04916
KEGG pathway: Prostate cancer
05215
KEGG pathway: Wnt signaling pathway
04310
Reactome Event:Signaling by Wnt
195721
Reactome Event:Signalling by NGF
166520
Products similar to GSK3B antibody:
IgG
GSK3 alpha & beta (ready-to-use), IgG
GSK3 alpha & beta, IgG
PRODUCT INTERACTIONS:
Rabbit anti GSK3b pS9
interacts
with
RAC-alpha serine/threonine-protein kinase, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1 Human, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKAkt1/PKBa Human, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
RAC-alpha serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
RAC-alpha serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt1 (inactive) HUMAN, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKBa (Akt1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Phospho-Ser473), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Ab-473), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Phospho-Thr308), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Ab-308), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Phospho-Ser473) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt (Phospho-Thr308) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKB, dephospho-Ser 473, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKB, pS 473, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKB/Akt, C-terminal, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Rabbit anti PKB (AKT) pS473, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Rabbit anti PKB (AKT) pT308, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Rabbit anti PKB (AKT) (460-480), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKB (AKT) (460-480) Peptide, Native_Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKAkt1/PKBa Human, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1 (v-akt murine thymoma viral oncogene homolog 1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-AKT (Human/Mouse/Rat /Chicken specific), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-AKT phospho specific pS473, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-AKT phospho specific pT308, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-IL-7 Receptor alpha chain pY449, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT1, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
RAC-beta serine/threonine-protein kinase, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt2 (inactive) HUMAN, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
PKBb (Akt2), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt2 (Phospho-Ser474), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt2 (Ab-474), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Akt2 (Phospho-Ser474) Antibody Blocking Peptide, Peptide
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Rabbit anti PKB beta (AKT2), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-AKT2, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
AKT2, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Gemin 3, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Gemin3, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Gemin 3 [12H12], IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Glyco.Synthase Kin.3b, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Anti-Human Muscle Glycogen Synthase pS640, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Glycogen synthase phospho S640, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SF3B1 (splicing factor 3b. subunit 1. 155kDa), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SMN (Gemin1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SMN (Gemin1), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
Human anti Human RNP Antigen, IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
U1snRNP-68 Human, Protein
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
SNRP70 (small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)), IgG
(GenWay Catalog #: 18-511-244379)
.
Rabbit anti GSK3b pS9
interacts
with
STRAP (serine/threonine kinase receptor associated protein), IgG
(GenWay Catalog #: 18-511-244379)
.
SUGGESTED ANITBODY REAGENTS
- GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
Order Confirmation:
Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions:
GSK3B antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes:
During shipment, small volumes of GSK3B antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright:
This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GSK3B antibody, all related information, articles, resources about GSK3B antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer:
For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.
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