KITLG antibody, Rabbit anti Human SCF Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

Rabbit anti Human SCF Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-511-244644

Buy KITLG antibody -

Size:

Related Product Names:

- KITLG antibody; KITLG; MGF; SCF; Rabbit anti Human SCF
- Rabbit anti Human SCF; C-kit ligand; Stem cell factor; SCF; Mast cell growth factor; MGF; Kit ligand

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: KITLG	Gene Name Synonym: MGF; SCF
Gi #: N/A	NCBI Acc #: NP_000890.1	Swiss Prot Acc #: P21583
Length (aa): N/A	Mol. Weight (Da): 30899	Chrom Location: N/A

Host Animal: Rabbit

Immunogen: Recombinant Human SCF

Specificity: Stem Cell Factor (SCF)

Specificity: Human Stem Cell Factor (SCF)

Type of Product: Polyclonal Antibodies to Cytokines and Growth Factors

Concentration: 1mg/ml (prior to lyophilization)

Buffer: Lyophilized from 0.5X PBS, pH 7.4.

Applications Notes : Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of human SCF (10.0ng/ml), a concentration of 0.008 – 0.012ug/ml of this antibody is required.. ELISA: By direct ELISA (using 100ul/well antibody solution) a concentration of at least 0.5ug/ml of this antibody is required to allow the detection of 0.2 – 0.4ng/well of recombinant human SCF.. Western blot: Can be used at a concentration of 0.1 – 0.2ug/ml to detect 1.5 – 3.0ng/lane recombinant human SCF, under reducing or non-reducing conditions.. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Source/Host: Rabbit

Purity/Purification: Immunoaffinity chromatography using immobilized human SCF matrix. Product is sterile filtered.

Clonality: Polyclonal

Format: Affinity Purified, Lyophilized Reconstitute in sterile water to a concentration of >0.2mg/ml.

Storage: The lyophilized product though stable (up to 1 month) at room temperature, is best stored at -20 C. After reconstitution, store (up to 6 weeks) at 2-8 C.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for KITLG ANTIBODY:

ELISA, Neut, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

KITLG ANTIBODY TARGET DESCRIPTION:

Synonym Names for KITLG antibody: KITLG; MGF; SCF; Rabbit anti Human SCF; C-kit ligand; Stem cell factor; SCF; Mast cell growth factor; MGF; Kit ligand

Rabbit anti Human SCF. Rabbit Antibody to Human Stem Cell Factor (SCF)

Function: Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins.

Subunit: Homodimer, non-covalently linked (Probable).

Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein (By similarity). Secreted (By similarity). Note=Also exists as a secreted soluble form (isoform 1 only) (By similarity).

Subcellular Location: Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasm, cytoskeleton (By similarity).

Developmental Stage: Acts in the early stages of hematopoiesis.

Ptm: A soluble form is produced by proteolytic processing of isoform 1 in the extracellular domain.

Ptm: Found in two differentially glycosylated forms, LMW-SCF and HMW-SCF. LMW-SCF is fully N-glycosylated at Asn-145, partially N-glycosylated at Asn-90, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97 or Asn-118. HMW-SCF is N-glycosylated at Asn-118, Asn-90 and Asn-145, O-glycosylated at Ser-167, Thr-168 and Thr-180, and not glycosylated at Asn-97.

Polymorphism: Genetic variations in KITLG are associated with variation in skin/hair/eye pigmentation type 7 (SHEP7) [MIM:611664]. Hair, eye and skin pigmentation are among the most visible examples of human phenotypic variation, with a broad normal range that is subject to substantial geographic stratification. In the case of skin, individuals tend to have lighter pigmentation with increasing distance from the equator. By contrast, the majority of variation in human eye and hair color is found among individuals of European ancestry, with most other human populations fixed for brown eyes and black hair.

Similarity: Belongs to the SCF family.

OMIM: 184745; gene. [NCBI / EBI]
611664; phenotype. [NCBI / EBI]

Pathways:
KEGG pathway: Cytokine-cytokine receptor interaction 04060
KEGG pathway: Hematopoietic cell lineage 04640
KEGG pathway: Melanogenesis 04916

Products similar to KITLG antibody:

IgG

c-Kit [104D2], IgG

c-Kit phospho Y823, IgG

c-Kit phospho Y568, Y570, IgG

c-Kit (ready-to-use), IgG

STAT5a, IgG

Protein

STEM CELL FACTOR, Protein

SCF Mouse, Protein

SCF (Stem Cell Factor), Protein

Mouse Stem Cell Factor, Protein

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PRODUCT INTERACTIONS:

Rabbit anti Human SCF interacts with CD117, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with cKit HUMAN, Protein (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit (Phospho-Tyr721), IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with CD117, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with Rat Anti-Mouse CD117/c-Kit, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit [104D2] (PE), IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit [104D2], IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with CD117, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit phospho Y730, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit phospho Y823, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit phospho Y936, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit phospho Y568, Y570, IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit (phospho Y721), IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with CD117 [2B8], IgG (GenWay Catalog #: 18-511-244644).

Rabbit anti Human SCF interacts with c-Kit (ready-to-use), IgG (GenWay Catalog #: 18-511-244644).

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: KITLG antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of KITLG antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about KITLG antibody, all related information, articles, resources about KITLG antibody are being stored on our online database. Let us know if you have questions regarding this product.

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