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| Goat anti HIV-1 p24 Antibody, Goat Polyclonal Antibody |
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| Catalog Number: 18-511-245219 |
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| Related Product Names:
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gag antibody; gag; Goat anti HIV-1 p24
- Goat anti HIV-1 p24; Pr55Gag; Gag polyprotein |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: gag |
Gene Name Synonym: N/A |
Gi #:
N/A |
NCBI Acc #:
N/A |
Swiss Prot Acc #:
O93182 |
Length (aa): N/A |
Mol. Weight (Da): 55674 |
Chrom Location: N/A |
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 Host Animal: Goat
Immunogen: Purified native p24 from strain IIIB
Specificity: HIV-1 p24
Specificity: p24 (predominate p24 band pattern in Western blot). Does not cross-react with human T or B cells. Not reactive with human or bovine sera.
Type of Product: Polyclonal Antibodies to Infectious Agents and Toxins
Concentration: 4-5mg/ml (OD280nm. E0.1% = 1.4)
Preservatives: 0.1% Sodium azide
Buffer: 0.01M PBS. pH 7.2. This product contains no stabilizing proteins.
Applications Notes : Avidin and streptavidin amplification systems for ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.. Recommended antibody pair for sandwich ELISA.. Capture Detection. 20-511-241432 18-511-245219
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Source/Host: Goat
Purity/Purification: Purified IgG fraction covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution
Clonality: Polyclonal
Format: Biotin, Liquid
Storage: Short-term (up to 6 months) store at 2-8 C. Long term, aliquot and store at -20 C.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for GAG ANTIBODY: |
| Pr-ELISA: Tested |
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| GAG ANTIBODY TARGET DESCRIPTION: |
Synonym Names for gag antibody: gag; Goat anti HIV-1 p24; Pr55Gag; Gag polyprotein
Goat anti HIV-1 p24. Goat Antibody to Human Immunodeficiency Virus Type 1 (HIV-1), p24. Biotin conjugated
Function: Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu (By similarity).
Function: Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).
Function: Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).
Function: p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity).
Subunit: Matrix protein p17 is a trimer. Interacts with gp120. p6-gag interacts with human TSG101 and PDCD6IP/AIP1 (By similarity).
Subcellular Location: Matrix protein p17: Virion (Potential). Nucleus (By similarity). Cytoplasm (By similarity). Cell membrane; Lipid-anchor (Potential). Note=Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity).
Subcellular Location: Capsid protein p24: Virion (Potential).
Subcellular Location: Nucleocapsid protein p7: Virion (Potential).
Domain: Late-budding domains (L domains) are short sequence motifs essential for viral particle release. They can occur individually or in close proximity within structural proteins. They interacts with sorting cellular proteins of the multivesicular body (MVB) pathway. Most of these proteins are class E vacuolar protein sorting factors belonging to ESCRT-I, ESCRT-II or ESCRT-III complexes. p6-gag contains two L domains: a PTAP/PSAP motif, which interacts with the UEV domain of TSG101 and a LXXLF motif which interacts with PDCD6IP/AIP1 (By similarity).
Ptm: Capsid protein p24 is phosphorylated (By similarity).
Ptm: Specific enzymatic cleavages by the viral protease yield mature proteins. The polyprotein is cleaved during and after budding, this process is termed maturation (By similarity).
Miscellaneous: HIV-1 lineages are divided in three main groups, M (for Major), O (for Outlier), and N (for New, or Non-M, Non-O). The vast majority of strains found worldwide belong to the group M. Group O seems to be endemic to and largely confined to Cameroon and neighboring countries in West Central Africa where these viruses represent a small minority of HIV-1 strains. The group N is represented by a limited number of isolates from Cameroonian persons. The group M is further subdivided in 9 clades or subtypes (A to D, F to H, J and K).
Similarity: Belongs to the primate lentivirus group gag polyprotein family.
Similarity: Contains 2 CCHC-type zinc fingers.
Products similar to gag antibody:
IgG
 HTLV I p19 [8.A.024], IgG
GAGA-POZ, Protein
GAGA-POZ domain (1-130aa), Drosophila melanogaster Recombinant, Protein
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: gag antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of gag antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about gag antibody, all related information, articles, resources about gag antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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