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Anti-TGF beta 1 specific Antibody, Rabbit N/A Antibody Printer Friendly Datasheet
Catalog Number: 18-732-292403
Buy TGFB1 antibody - Size:   
  Related Product Names:
- TGFB1 antibody; TGFB1; TGFB; Anti-TGF beta 1 specific
- Affinity Purified Anti-TGF?1 Specific (Human) (Rabbit); TGF-beta-1; Transforming growth factor beta-1
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: TGFB1  Gene Name Synonym: TGFB

 Gi #: N/A

 NCBI Acc #: NP_000651.3

 Swiss Prot Acc #: P01137

 Length (aa): N/A

 Mol. Weight (Da): 44341

 Chrom Location: N/A
 Antigen: TGF beta 1 specific (Human)

 Peptide Sequence: F-S-S-T-E-K-N

 Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 286-293 (of 390) of full-length (including signal peptide) TGF?. This peptide corresponds with aa 8-15 (of 112) of the mature growth factor.

 Family: Cytokines

 Fraction: Affinity Purified IgG

 Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Reactivity in other immunoassays is unknown.

 Recommended Dilution: This product has been assayed by ELISA against 0.1 ug of the immunizing peptide. A 1:1,000 to 1:3,000 dilution of the antibody is recommended for this assay.

 Physical State: Liquid (sterile filtered)

 Purity and Specificity: This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.

 Antibody Concentration: 0.64 mg/ml (by UV absorbance at 280 nm)

 Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

 Stabilizer: None

 Ship Code: DRYICE

 Source/Host: Rabbit

 Purity/Purification: Affinity Purified

 Crossreactivity: Human, Bovine, Mouse, Rat

 Format: Liquid (sterile filtered)

 Storage: -20C or Colder

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for TGFB1 ANTIBODY:
 ELISA, WB, IP: Tested
 TESTING: (secondary reagents and protocols )
 Not Available
 TGFB1 ANTIBODY TARGET DESCRIPTION:
Synonym Names for TGFB1 antibody: TGFB1; TGFB; Affinity Purified Anti-TGF?1 Specific (Human) (Rabbit); TGF-beta-1; Transforming growth factor beta-1

Function: Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Subunit: The inactive form consists of a TGFB1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The inactive complex can contain a latent TGFB1-binding protein. The active form is a homodimer of mature TGFB1; disulfide-linked. Heterodimers of TGFB1/TGFB2 have been found in bone. Interacts with CD109 and DPT.

Subcellular Location: Secreted.

Tissue Specificity: Highly expressed in bone.

Induction: Activated in vitro at pH below 3.5 and over 12.5.

Ptm: Glycosylated.

Ptm: The precursor is cleaved into mature TGF-beta-1 and LAP, which remains non-covalently linked to mature TGF-beta-1 rendering it inactive.

Polymorphism: In post-menopausal Japanese women, the frequency of Leu-10 is higher in subjects with osteoporosis than in controls.

Disease: Defects in TGFB1 are the cause of Camurati-Engelmann disease (CED) [MIM:131300]; also known as progressive diaphyseal dysplasia 1 (DPD1). CED is an autosomal dominant disorder characterized by hyperostosis and sclerosis of the diaphyses of long bones. The disease typically presents in early childhood with pain, muscular weakness and waddling gait, and in some cases other features such as exophthalmos, facial paralysis, hearing difficulties and loss of vision.

Similarity: Belongs to the TGF-beta family.

Anti-TGF beta 1 specific reacts with human, bovine, mouse, rat.

OMIM: 131300; phenotype. [NCBI / EBI]
190180; gene. [NCBI / EBI]

Products similar to TGFB1 antibody:
 IgG
    TGFB1, IgG
    TGF beta 3 (ready-to-use), IgG
    TGF beta 3, IgG
    TGF beta [2C5], IgG
    TGFB1, IgG
 Peptide
    TGF BETA 1, Peptide
    BIGH3 Human, Protein
    BIGH3, Fasciclin domain 4, Protein
    Transforming Growth Factor beta 2 (Human), E coli, Protein
    TGF BETA 1, Protein
 PRODUCT INTERACTIONS:
 Anti-TGF beta 1 specific interacts with Amyloid beta A4 protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid beta A4 protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with AMYLOID BETA, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Anti Human Beta Amyloid Protein 1-40 (Anti-betaAP1-40), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Anti Human Beta Amyloid Protein 17-42 (Anti-betaAP17-42), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Anti-Human Beta Amyloid Protein Monoclonal Antibody (Anti-Human betaAP), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein [3E9], IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with beta Amyloid [2C8], IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein Frameshift Mutant, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with beta Amyloid [3G5], IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with beta Amyloid [BAM-10], IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Beta Amyloid N-term. (a.a. 1-8), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Beta Amyloid N-term. (a.a. 1-8), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Beta Amyloid a.a. 1-17, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit anti Beta Amyloid 1-42, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit anti Beta Amyloid 1-40, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit A' Amyloid Precursor Pro.(a.a.653-662), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit A' Amyloid Precursor Pro.(a.a.737-751), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit anti Amyloid, Beta, N-terminal, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Rabbit anti Rat/Mouse Beta Amyloid (3-16), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Goat A'Amyloid Pre.Pro. Frame (C-term), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein C-term Peptide, Peptide (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Anti-Beta Amyloid, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein (ready-to-use), IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with beta Amyloid [DE2B4], IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Beta Amyloid, IgG (GenWay Catalog #: 18-732-292403).
 Anti-TGF beta 1 specific interacts with Amyloid Precursor Protein, IgG (GenWay Catalog #: 18-732-292403).
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: TGFB1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of TGFB1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about TGFB1 antibody, all related information, articles, resources about TGFB1 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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