ALPL secondary antibody, Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgM (mu chain) (GOAT) Secondary Antibody

Alphabetical Listing of Primary Antibodies:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Alphabetical Listing of Proteins:	f\| 0-4 \| 5-9 \| A \| B \| C \| D \| E \| F \| G \| H \| I \| J \| K \| L \| M \| N \| O \| P \| Q \| R \| S \| T \| U \| V \| W \| X \| Y \| Z \|
Peptides \| Secondary Antibodies \| ELISA Kits

Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgM (mu chain) (GOAT) Secondary Antibody

Catalog Number: 25-732-294276

Buy ALPL secondary antibody -

Size:

Related Product Names:

- ALPL secondary antibody; ALPL; Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgM (mu chain) (GOAT)
- Alkaline Phosphatase Conjugated Affinity Purified anti-Mouse IgM ? (mu chain specific) [Goat]; EC 3.1.3.1; AP-TNAP; TNSALP; Alkaline phosphatase liver/bone/kidney isozyme; Alkaline phosphatase, tissue-nonspecific isozyme

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ALPL	Gene Name Synonym: N/A
Gi #: N/A	NCBI Acc #: NP_000469.3	Swiss Prot Acc #: P05186
Length (aa): N/A	Mol. Weight (Da): 57305	Chrom Location: N/A

Antigen: IgM or Mu Heavy Chain

Immunogen: Mouse IgM ? chain

Family: Affinity Purified

Fraction: Affinity Purified IgG

Purity Note: This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgM coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities.Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Alkaline Phosphatase (cal fintestine), anti-Goat Serum, Mouse IgM and Mouse Serum. Specificity was confirmed by ELISA at less than 1% cross-reactivity against other mouse or human heavy or light chain isotypes.

Conjugation: Alklaine Phosphatase

Conjugation Reference: Modified from Avarameas and Ternyrock, Immunochemistry 32; 1175, 1971.

Application: Suitable for immunoblotting (western or dot blot), ELISA and immunohistochemistry as well as other phosphatase-antibody based enzymatic assays requiring lot-to-lot consistency.

Recommended Dilution: ELISA 1:4,500 - 1:6,500
WESTERN BLOT 1:500 - 1:2,500
IMMUNOHISTOCHEMISTRY 1:200 - 1:1,000

Physical State: Liquid (sterile filtered)

Antibody Concentration: 1.0 mg/ml (by UV absorbance at 280 nm)

Label: Alkaline Phosphatase (Calf Intestine) (Molecular Weight 140,000 daltons)`

Buffer: 0.05M Tris Chloride, 0.15M Sodium Chloride, 0.001M Magnesium Chloride, 0.0001M Zinc Chloride,50% (v/v) Glycerol; pH 8.0

Stabilizer: 10 mg/ml Bovine Serum Albumin (BSA), IgG and Protease free

Ship Code: WETICE

Source/Host: Goat

Purity/Purification: Affinity Purified

Crossreactivity: Mouse IgM (mu chain)

Format: Liquid (sterile filtered)

Storage: 4C

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ALPL SECONDARY ANTIBODY:

WB, ELISA, IHC: Tested

TESTING: (secondary reagents and protocols )

Not Available

ALPL SECONDARY ANTIBODY TARGET DESCRIPTION:

Synonym Names for ALPL secondary antibody: ALPL; Alkaline Phosphatase Conjugated Affinity Purified anti-Mouse IgM ? (mu chain specific) [Goat]; EC 3.1.3.1; AP-TNAP; TNSALP; Alkaline phosphatase liver/bone/kidney isozyme; Alkaline phosphatase, tissue-nonspecific isozyme

Function: This isozyme may play a role in skeletal mineralization.

Catalytic Activity: A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor: Binds 1 magnesium ion (By similarity).

Cofactor: Binds 2 zinc ions (By similarity).

Subunit: Homodimer.

Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor.

Ptm: Glycosylated.

Disease: Defects in ALPL are a cause of hypophosphatasia infantile (hypophosphatasia) [MIM:241500]; an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and adult type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia (odonto).

Disease: Defects in ALPL are a cause of hypophosphatasia childhood (hypophosphatasia) [MIM:241510].

Disease: Defects in ALPL are a cause of hypophosphatasia adult type (hypophosphatasia) [MIM:146300].

Miscellaneous: In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).

Similarity: Belongs to the alkaline phosphatase family.

Alkaline Phosphatase Conjugated Affinity Purified Anti-MOUSE IgM (mu chain) (GOAT) reacts with mouse igm (mu chain).

OMIM: 146300; phenotype. [NCBI / EBI]
171760; gene. [NCBI / EBI]
241500; phenotype. [NCBI / EBI]
241510; phenotype. [NCBI / EBI]

Pathways:
KEGG pathway: Folate biosynthesis 00790
KEGG pathway: gamma-Hexachlorocyclohexane degradation 00361

Products similar to ALPL secondary antibody:

IgG

Alkaline Phosphatase *B1G1, IgG

Alkaline Phosphatase, IgG

Bone Alkaline Phosphatase [0.G.2], IgG

Alkaline Phosphatase, IgG

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ALPL secondary antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ALPL secondary antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ALPL secondary antibody, all related information, articles, resources about ALPL secondary antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.



GenWay Biotech, Inc. 6777 Nancy Ridge Drive, San Diego, CA 92121 Tel: (858)458-0866 Fax: (858)458-0833 Email: sales@genwaybio.com www.genwaybio.com ©1998 - 2010 GenWay Biotech, Inc. - All Rights Reserved