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| CD115 Antibody, Rat Monoclonal Antibody |
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| Catalog Number: 20-783-310191 |
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| Related Product Names:
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CD115 antibody; CD115; FMS; CD115
- RAT ANTI MOUSE CD115; Macrophage colony-stimulating factor 1 receptor |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: CD115 |
Gene Name Synonym: FMS |
Gi #:
N/A |
NCBI Acc #:
NP_005202.2 |
Swiss Prot Acc #:
P09581 |
Length (aa): N/A |
Mol. Weight (Da): 107984 |
Chrom Location: N/A |
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 Specificity: CD115
NCBI Gene ID: 12978
Isotype: Specificity: CD115
Clone: 604B5 2E11
Immunogen: Raw 264 cells
Fusion Partner: Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653 myeloma cell line.
Preparation: Purified IgG prepared by ion exchange chromatography
Buffer Solution: Phosphate buffered saline pH7.4
Preservative Stabilisers:
Suggested Dilution: Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Suggested Dilution: Flow Cytometry - 1/25 - 1/50
Source/Host: Rat
Clonality: Monoclonal
Crossreactivity: Target Species: Mouse
Reacts with: Rat N.B.
Format: Purified
Storage: Store at +4 degree C or at -20 degree C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability: 18 months from date of despatch.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for CD115 ANTIBODY: |
| FACS/FC: Tested |
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| CD115 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for CD115 antibody: CD115; FMS; RAT ANTI MOUSE CD115; Macrophage colony-stimulating factor 1 receptor
Function: Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
Catalytic Activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subunit: Interacts with INPPL1/SHIP2 and THOC5 (By similarity).
Subcellular Location: Membrane; Single-pass type I membrane protein.
Tissue Specificity: Expressed in bone marrow and in differentiated blood mononuclear cells.
Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Similarity: Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Similarity: Contains 1 protein kinase domain.
CD115 reacts with target species: mouse
reacts with: rat n.b..
OMIM: 164770; gene. [NCBI / EBI]
Pathways:
KEGG pathway: Cytokine-cytokine receptor interaction 04060
KEGG pathway: Hematopoietic cell lineage 04640
Products similar to CD115 antibody:
IgG
 MCSF receptor, IgG
CSF1R [2-4A5-4 (Workshop V)], IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for CD115 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| 1. Shadduck. R.K. et al. (1996) Paradoxical stimulation of normal and leukemic rat hematopoiesis by monoclonal antibody to CSF-I receptor. 2. Gilmore. G.L. et al. (1995) Inhibition of day-12 spleen colony-forming units by a monoclonal antibody to the murine macrophage/monocyte colony-stimulating factor receptor. 3. MacDonald. K.P.A. et al. (2005) The colony stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: CD115 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of CD115 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about CD115 antibody, all related information, articles, resources about CD115 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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