XRCC3 antibody, XRCC3 Antibody, Rabbit Polyclonal Antibody

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XRCC3 Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-783-313044

Buy XRCC3 antibody -

Size:

Related Product Names:

- XRCC3 antibody; XRCC3; XRCC3
- RABBIT ANTI HUMAN XRCC3; DNA repair protein XRCC3

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: XRCC3	Gene Name Synonym: N/A
Gi #: N/A	NCBI Acc #: NP_001093588.1	Swiss Prot Acc #: O43542
Length (aa): N/A	Mol. Weight (Da): 37850	Chrom Location: N/A

Specificity: XRCC3

NCBI Gene ID: 7517

Isotype: Specificity: XRCC3

Immunogen: Synthetic partial peptide of human XRCC3.

Specificity Note: This product recognises human X-ray repair cross-complementing protein 3 (XRCC3), a 37.9 kDa nuclear DNA repair protein belonging to the RecA/Rad51 related protein family.

The XRCC3 protein functions in homologous recombination to maintain chromosome stability and facilitate DNA damage repair. XRCC3 is also required for correct chromosomal segregation and for the repair of DNA cross links.

Studies indicate that XRCC3 is involved at an early stage in the repair process. XRCC3 interacts with RAD51C to form a complex which is recruited to the site of DNA damage. Defects in vertebrate XRCC3 result in elevated levels of spontaneous DNA damage induced chromosomal abnormalities and increased sensitivity to DNA damaging agents.

Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Histology: Human prostate

Antiserum Preparation: Antiserum to human XRCC3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer Solution: Phosphate buffered saline

Preservative Stabilisers: 0.05% Sodium Azide (NaN₃)

Suggested Dilution: Suggested Dilution: Immunohistology - Paraffin - 5ug/ml
Western Blotting - 1:5000

Source/Host: Rabbit

Clonality: Polyclonal

Crossreactivity: Human

Format: Purified

Storage: Store at +4 degree C or at -20 degree C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Stability: 18 months from date of despatch.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for XRCC3 ANTIBODY:

IHC-F, WB: Tested

TESTING: (secondary reagents and protocols )

Not Available

XRCC3 ANTIBODY TARGET DESCRIPTION:

Synonym Names for XRCC3 antibody: XRCC3; RABBIT ANTI HUMAN XRCC3; DNA repair protein XRCC3

Function: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.

Subunit: Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.

Subcellular Location: Nucleus (Probable).

Ptm: Phosphorylated upon DNA damage, probably by ATM or ATR.

Disease: Met-241 is associated with the development of cutaneous malignant melanoma.

Similarity: Belongs to the recA family. RAD51 subfamily.

XRCC3 reacts with human.

OMIM: 600675; gene. [NCBI / EBI]

Products similar to XRCC3 antibody:

IgG

XRCC3 (ready-to-use), IgG

XRCC3, IgG

XRCC3 [XRCC3 10F1/6], IgG

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: XRCC3 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of XRCC3 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about XRCC3 antibody, all related information, articles, resources about XRCC3 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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