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| Visfatin recombinant protein |
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| Catalog Number: 10-002-38139 |
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| Related Product Names:
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Visfatin protein; Visfatin
- Visfatin, 1-491aa, Human, His-tagged, Recombinant, E Coli; N/A; Nicotinamide phosphoribosyltransferase; N/A |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: N/A |
Gene Name Synonym: N/A |
Gi #:
5031977 |
NCBI Acc #:
NP_005737.1 |
Swiss Prot Acc #:
N/A |
Length (aa): 491 |
Mol. Weight (Da): N/A |
Chrom Location: N/A |
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 Synonyms: NAMPT, MGC117256
Molecular Weight: 57 kDa (511 aa)
Sequence: MGSSHHHHHH SSGLVPRGSH MNPAAEAEFN ILLATDSYKV THYKQYPPNT SKVYSYFECR EKKTENSKLR KVKYEETVFY GLQYILNKYL KGKVVTKEKI QEAKDVYKEH FQDDVFNEKG WNYILEKYDG HLPIEIKAVP EGFVIPRGNV LFTVENTDPE CYWLTNWIET ILVQSWYPIT VATNSREQKK ILAKYLLETS GNLDGLEYKL HDFGYRGVSS QETAGIGASA HLVNFKGTDT VAGLALIKKY YGTKDPVPGY SVPAAEHSTI TAWGKDHEKD AFEHIVTQFS SVPVSVVSDS YDIYNACEKI WGEDLRHLIV SRSTQAPLII RPDSGNPLDT VLKVLEILGK KFPVTENSKG YKLLPPYLRV IQGDGVDINT LQEIVEGMKQ KMWSIENIAF GSGGGLLQKL TRDLLNCSFK CSYVVTNGLG INVFKDPVAD PNKRSKKGRL SLHRTPAGNF VTLEEGKGDL EEYGQDLLHT VFKNGKVTKS YSFDEIRKNA QLNIELEAAH H
Concentration: 1mg/ml
Purity/Purification: >= 95% by SDS PAGE
Format: Liquid in 20mM Tris pH 8.0, 0.1mM DTT, 10% glycerol
Storage: Store at -20C. Avoid freeze/thaw cycle.
Shipping: Products may be shipped on ice pack or dry ice. |
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| VISFATIN PROTEIN TARGET DESCRIPTION: |
Synonym Names for Visfatin protein: N/A; Visfatin, 1-491aa, Human, His-tagged, Recombinant, E Coli; N/A; Nicotinamide phosphoribosyltransferase; N/A
Visfatin is pre-B cell colony-enhancing factor 1 (PBEF), which is predominantly secreted from visceral adipose tissue both in humans and mice. This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis, or a visceral-fat derived hormone that acts by binding and activating the insulin receptor. Recombinant human visfatin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Summary: This protein is a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This protein has a pseudogene on chromosome 10. [provided by RefSeq].
OMIM: NCBI [608764]
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SUGGESTED PROTEIN REAGENTS - GenWay offers reagents to facilitate your research with cell-based assays, Mass Spectrometry, standards, calibrators, Western blot, cell culture, antibiotics, microwell substrates, and more!
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| BACKGROUND
REFERENCES for VISFATIN PROTEIN: |
| Background references for antibody target are not specific to GenWay products |
1. Stephens JM., et al. (2006) Curr Opin Lipidol. 17:128-31.
1. Hug C, Lodish HF., et al (2005) Science. 307:36-97. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: Visfatin protein is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of Visfatin protein vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about Visfatin protein, all related information, articles, resources about Visfatin protein are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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GenWay is a Protein and Antibody Solutions Provider. Customer Satisfaction is Our Top Priority.
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GenWay has a diverse line of recombinant protein expression platforms, including E. coli expression, Bacliovirus expression, yeast expression, and mammalian expression. Combining the technologies of bioinformatics, protein domain analysis, gene codon optimization, protein fusion, and protein expression in different host cells, GenWay can produce soluble and functional proteins. In particular, GenWay has the capability and vector systems for expression of difficult proteins such as proteases, kinases, glycosylated and membrane proteins. We have a very high success rate (almost 100%) and can deliver the proteins in a timely fashion. This is a core competency necessary for efficient and effective production of immunogens and affinity ligands for antibody production and purification. GenWay has over 300 recombinant proteins offered in our catalog. |
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