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| GFI1 (growth factor independent 1) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-42241 |
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| Trial Size Available. Please expect delivery of trial size products to be 4 weeks. |
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| Related Product Names:
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GFI1 antibody; GFI1; ZNF163; GFI1 (growth factor independent 1)
- Growth factor independent protein 1; Zinc finger protein 163; Growth factor independent 1; Zinc finger protein Gfi-1 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: GFI1 |
Gene Name Synonym: ZNF163 |
Gi #:
71037377 |
NCBI Acc #:
NP_005254.2 |
Swiss Prot Acc #:
Q99684 |
Length (aa): 422 |
Mol. Weight (Da): 45297 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human GFI1.
ELISA Titre: 1:12500
Category: Transcription Factor Antibodies
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit Ig G is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Crossreactivity: Human
Format: Suggested dilution at 0.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for GFI1 ANTIBODY: |
| WB: Tested |
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| GFI1 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for GFI1 antibody: GFI1; ZNF163; Growth factor independent protein 1; Zinc finger protein 163; Growth factor independent 1; Zinc finger protein Gfi-1
GFI1 in prostate cancer cells acts as a repressor of 25-hydroxyvitamin D 1-alpha hydroxylase gene.
Function: May be a transcription factor involved in regulating the expression of genes active in the S phase during cell cycle progression in T-cells. May be involved in tumor progression (By similarity). Represses ELA2 transcription.
Subunit: Interacts with U2AF1L4 (By similarity).
Subcellular Location: Nucleus.
Domain: The Gly/Ala-rich region may indicate that Gfi-1 is a repressor of its target genes.
Disease: Defects in GFI1 are a cause of autosomal dominant severe congenital neutropenia (SCN) [MIM:202700].
Disease: Defects in GFI1 are a cause of dominant nonimmune chronic idiopathic neutropenia of adults (NI-CINA) [MIM:607847]. NI-CINA is a relatively mild form of neutropenia diagnosed in adults, but predisposing to leukemia in a subset of patients.
Similarity: Contains 6 C2H2-type zinc fingers.
GFI1 (growth factor independent 1) reacts with human.
OMIM: 202700; phenotype. [NCBI / EBI]
600871; gene. [NCBI / EBI]
607847; phenotype. [NCBI / EBI]
Products similar to GFI1 antibody:
IgG
 GFI1 (growth factor independent 1), IgG
GFI1B (growth factor independent 1B (potential regulator of CDKN1A. translocated in CML)), IgG
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| PRODUCT INTERACTIONS: |
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for GFI1 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Doan.L.L.. et al.. (2004) Nucleic Acids Res. 32 (8). 2508-2519. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: GFI1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of GFI1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about GFI1 antibody, all related information, articles, resources about GFI1 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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