ACSL1 antibody, ACSL1 (acyl-CoA synthetase long-chain family member 1) Antibody, Rabbit Polyclonal Antibody

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Peptides \| Secondary Antibodies \| ELISA Kits

ACSL1 (acyl-CoA synthetase long-chain family member 1) Antibody, Rabbit Polyclonal Antibody

Catalog Number: 18-003-42285

Buy ACSL1 antibody -

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Related Product Names:

- ACSL1 antibody; ACSL1; ACS1, FACL1, FACL2, LACS, LACS1, LACS2; ACSL1 (acyl-CoA synthetase long-chain family member 1)
- EC 6.2.1.3; Long-chain acyl-CoA synthetase 1; LACS 1; Palmitoyl-CoA ligase 1; Long-chain fatty acid-CoA ligase 2; Long-chain acyl-CoA synthetase 2; LACS 2; Acyl-CoA synthetase 1; ACS1; Palmitoyl-CoA ligase 2; Acyl-CoA synthetase long-chain family member 1; Long-chain-fatty-acid--CoA ligase 1

- Gene Information - Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.

Gene Name: ACSL1	Gene Name Synonym: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Gi #: 40807491	NCBI Acc #: NP_001986.2	Swiss Prot Acc #: P33121
Length (aa): 698	Mol. Weight (Da): 77943	Chrom Location: N/A

Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ACSL1.

ELISA Titre: 1:312500

Category: Membrane Protein

Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.

Source/Host: Rabbit

Purity/Purification: Rabbit Ig G is purified by peptide affinity chromatography method.

Clonality: Polyclonal

Crossreactivity: Human

Format: Suggested dilution at 0.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.

Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.

Stability: Note: Avoid repeat freeze-thaw cycles.

Shipping: Products may be shipped on ice pack or dry ice.

APPLICATIONS for ACSL1 ANTIBODY:

IHC-P. WB: Tested

TESTING: (secondary reagents and protocols [IHC Protocol])

IHC: ( anti-ACSL1 )

ACSL1 antibody IHC image
ACSL1

WB: ( anti-ACSL1 )

ACSL1 antibody WB image
ACSL1

ACSL1 ANTIBODY TARGET DESCRIPTION:

Synonym Names for ACSL1 antibody: ACSL1; ACS1, FACL1, FACL2, LACS, LACS1, LACS2; EC 6.2.1.3; Long-chain acyl-CoA synthetase 1; LACS 1; Palmitoyl-CoA ligase 1; Long-chain fatty acid-CoA ligase 2; Long-chain acyl-CoA synthetase 2; LACS 2; Acyl-CoA synthetase 1; ACS1; Palmitoyl-CoA ligase 2; Acyl-CoA synthetase long-chain family member 1; Long-chain-fatty-acid--CoA ligase 1

ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity. subcellular localization. and tissue distribution. all isozymes of this family convert free long-chain fatty acids into fatty acyl

Function: Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.

Catalytic Activity: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.

Cofactor: Magnesium.

Subcellular Location: Mitochondrion outer membrane; Single-pass type III membrane protein (By similarity). Peroxisome membrane; Single-pass type III membrane protein (By similarity). Microsome membrane; Single-pass type III membrane protein (By similarity). Endoplasmic reticulum membrane; Single-pass type III membrane protein (By similarity).

Tissue Specificity: Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.

Developmental Stage: Expressed during the early stages of erythroid development while expression is very low in reticulocytes and young erythrocytes.

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family.

Summary: The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.

ACSL1 (acyl-CoA synthetase long-chain family member 1) reacts with human.

OMIM: 152425; gene. [NCBI / EBI]

SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.

BACKGROUND REFERENCES for ACSL1 ANTIBODY:

Background references for antibody target are not specific to GenWay products

Ghosh.B.. et al.. (1995) Mol. Cell. Biochem. 151 (1). 77-81.

Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ACSL1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ACSL1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ACSL1 antibody, all related information, articles, resources about ACSL1 antibody are being stored on our online database. Let us know if you have questions regarding this product.

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