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| VDAC1 (voltage-dependent anion channel 1) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-42624 |
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| Related Product Names:
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VDAC1 antibody; VDAC1; MGC111064, PORIN, PORIN-31-HL; VDAC1 (voltage-dependent anion channel 1)
- VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; Voltage-dependent anion channel 1; Voltage-dependent anion-selective channel protein 1 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: VDAC1 |
Gene Name Synonym: MGC111064, PORIN, PORIN-31-HL |
Gi #:
4507879 |
NCBI Acc #:
NP_003365.1 |
Swiss Prot Acc #:
Q5FVE7 |
Length (aa): 283 |
Mol. Weight (Da): 30773 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human VDAC1.
ELISA Titre: 1:312500
Category: Tumor Suppressor Genes & Apoptosis
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit IgG purified by protein A chromatography.
Clonality: Polyclonal
Crossreactivity: Human
Format: Suggested dilution at 1.25 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for VDAC1 ANTIBODY: |
| IHC-P. WB: Tested |
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| VDAC1 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for VDAC1 antibody: VDAC1; MGC111064, PORIN, PORIN-31-HL; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; Voltage-dependent anion channel 1; Voltage-dependent anion-selective channel protein 1
The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane. the cell membrane. endosomes. caveolae. the sarcoplasmatic reticulum. synaptosomes. and post-synaptic density fra
Function: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Subunit: Interacts with hexokinases (By similarity). Interacts with influenza A virus PB1-F2 protein.
Subcellular Location: Mitochondrion outer membrane. Cell membrane.
Tissue Specificity: Heart, liver and skeletal muscle.
Domain: Consists mainly of membrane-spanning sided beta-sheets.
Similarity: Belongs to the eukaryotic mitochondrial porin family.
VDAC1 (voltage-dependent anion channel 1) reacts with human.
OMIM: 604492; gene+phenotype. [NCBI / EBI]
Products similar to VDAC1 antibody:
IgG
 VDAC1, IgG
Rabbit anti Porin/VDAC, IgG
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| PRODUCT INTERACTIONS: |
VDAC1 (voltage-dependent anion channel 1) interacts with Gamma-aminobutyric acid receptor-associated protein-like 2, Protein (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with KIF5B (kinesin family member 5B), IgG (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with KIF5B (kinesin family member 5B), IgG (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with MCC (88-103), Peptide (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with TNF receptor-associated factor 6, IgG (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with TRAF6, IgG (GenWay Catalog #: 18-003-42624).
VDAC1 (voltage-dependent anion channel 1) interacts with TRAF6, IgG (GenWay Catalog #: 18-003-42624).
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for VDAC1 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Zheng.Y.. et al.. (2004) Oncogene 23 (6). 1239-1247. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: VDAC1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of VDAC1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about VDAC1 antibody, all related information, articles, resources about VDAC1 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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