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| LZTS1 (leucine zipper. putative tumor suppressor 1) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-43277 |
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| Related Product Names:
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LZTS1 antibody; LZTS1; F37, FEZ1; LZTS1 (leucine zipper. putative tumor suppressor 1)
- F37/esophageal cancer-related gene-coding leucine-zipper motif; Fez1; Leucine zipper, putative tumor suppressor 1; Leucine zipper putative tumor suppressor 1 |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: LZTS1 |
Gene Name Synonym: F37, FEZ1 |
Gi #:
10440566 |
NCBI Acc #:
NP_066300.1 |
Swiss Prot Acc #:
Q9Y250 |
Length (aa): 596 |
Mol. Weight (Da): 66613 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human LZTS1.
ELISA Titre: 1:1562500
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit IgG purified by protein A chromatography.
Clonality: Polyclonal
Crossreactivity: Human
Format: Suggested dilution at 2.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for LZTS1 ANTIBODY: |
| WB: Tested |
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| LZTS1 ANTIBODY TARGET DESCRIPTION: |
Synonym Names for LZTS1 antibody: LZTS1; F37, FEZ1; F37/esophageal cancer-related gene-coding leucine-zipper motif; Fez1; Leucine zipper, putative tumor suppressor 1; Leucine zipper putative tumor suppressor 1
LZTS1 involved in the regulation of cell growth. LZTS1 may stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. LZTS1 may act as tumor suppressor and
Function: Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as tumor suppressor.
Subunit: Binds EEF1G and CDC2.
Subcellular Location: Cytoplasm (By similarity). Cell membrane (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell junction, synapse (By similarity). Note=Associated with the plasma membrane and with microtubules. Detected in dendritic spines, especially in the postsynaptic density (By similarity).
Tissue Specificity: Highly expressed in testis, prostate, spleen, thymus, ovary and brain. Detected at lower levels in heart, placenta, small intestine, colon, liver, kidney, skeletal muscle and pancreas. Not detectable in primary tumors from breast and prostate and in many cancer cell lines.
Ptm: Phorphorylated on serine residues. Hyperphosphorylated by the cAMP-dependent kinase PKA during cell-cycle progression.
Disease: Defects in LZTS1 are found in many types of tumors.
Similarity: Belongs to the LZTS family.
LZTS1 (leucine zipper. putative tumor suppressor 1) reacts with human.
OMIM: 606551; gene. [NCBI / EBI]
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| PRODUCT INTERACTIONS: |
LZTS1 (leucine zipper. putative tumor suppressor 1) interacts with cell division cycle 25 homolog C (S. cerevisiae) (CDC25C), IgG (GenWay Catalog #: 18-003-43277).
LZTS1 (leucine zipper. putative tumor suppressor 1) interacts with cdc25C (Phospho-Ser216), IgG (GenWay Catalog #: 18-003-43277).
LZTS1 (leucine zipper. putative tumor suppressor 1) interacts with cdc25C (Ab-216), IgG (GenWay Catalog #: 18-003-43277).
LZTS1 (leucine zipper. putative tumor suppressor 1) interacts with cdc25C (Phospho-Ser216) Antibody Blocking Peptide, Peptide (GenWay Catalog #: 18-003-43277).
LZTS1 (leucine zipper. putative tumor suppressor 1) interacts with CDC25C [DCS-193], IgG (GenWay Catalog #: 18-003-43277).
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for LZTS1 ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Hawkins.G.A.. et al.. (2002) Cancer Genet. Cytogenet. 137 (1). 1-7. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: LZTS1 antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of LZTS1 antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about LZTS1 antibody, all related information, articles, resources about LZTS1 antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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