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| MAFF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-43358 |
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| Related Product Names:
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MAFF antibody; MAFF; CTA-447C4.1, U-MAF; MAFF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian))
- V-maf musculoaponeurotic fibrosarcoma oncogene homolog F; U-Maf; Transcription factor MAFF; Transcription factor MafF |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: MAFF |
Gene Name Synonym: CTA-447C4.1, U-MAF |
Gi #:
23111003 |
NCBI Acc #:
NP_690617.1 |
Swiss Prot Acc #:
Q9ULX9 |
Length (aa): 164 |
Mol. Weight (Da): 17760 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human MAFF.
ELISA Titre: 1:62500
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit IgG purified by protein A chromatography.
Clonality: Polyclonal
Crossreactivity: Human
Format: Suggested dilution at 5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for MAFF ANTIBODY: |
| WB: Tested |
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| MAFF ANTIBODY TARGET DESCRIPTION: |
Synonym Names for MAFF antibody: MAFF; CTA-447C4.1, U-MAF; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F; U-Maf; Transcription factor MAFF; Transcription factor MafF
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containi
Function: Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. Since it lacks a putative transactivation domain, it may behave as a transcriptional repressor when it dimerize among himself. May also serve as a transcriptional activator by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. May be involved in the cellular stress response.
Subunit: Monomer and homo- or heterodimer.
Subcellular Location: Nucleus.
Tissue Specificity: Expressed in the term myometrium and kidney.
Induction: By oxidative stress.
Similarity: Belongs to the bZIP family. Maf subfamily.
Similarity: Contains 1 bZIP domain.
Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This protein may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
MAFF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)) reacts with human.
OMIM: 604877; gene. [NCBI / EBI]
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for MAFF ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Marini.M.G.. (2002) Blood Cells Mol. Dis. 29 (2). 145-158. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: MAFF antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of MAFF antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about MAFF antibody, all related information, articles, resources about MAFF antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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