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ELL (elongation factor RNA polymerase II) Antibody, Rabbit Polyclonal Antibody Printer Friendly Datasheet
Catalog Number: 18-003-43408
Buy ELL antibody - Size:   
  Related Product Names:
- ELL antibody; ELL; C19orf17, DKFZp434I1916, ELL1, ELL_HUMAN, Men; ELL (elongation factor RNA polymerase II)
- Eleven-nineteen lysine-rich leukemia protein; Elongation factor RNA polymerase II; RNA polymerase II elongation factor ELL
- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
 Gene Name: ELL  Gene Name Synonym: C19orf17, DKFZp434I1916, ELL1, ELL_HUMAN, Men

 Gi #: 5729812

 NCBI Acc #: NP_006523.1

 Swiss Prot Acc #: P55199

 Length (aa): 621

 Mol. Weight (Da): 68265

 Chrom Location: N/A
 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ELL.

 ELISA Titre: 1:312500

 Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.

 Source/Host: Rabbit

 Purity/Purification: Rabbit IgG purified by protein A chromatography.

 Clonality: Polyclonal

 Crossreactivity: Human, Dog

 Format: Suggested dilution at 7.5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.

 Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 microl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.

 Stability: Note: Avoid repeat freeze-thaw cycles.

 Shipping: Products may be shipped on ice pack or dry ice.
 APPLICATIONS for ELL ANTIBODY:
 IHC-P. WB: Tested
 TESTING: (secondary reagents and protocols [IHC Protocol])
 IHC: ( anti-ELL )

ELL antibody IHC image
ELL

 WB: ( anti-ELL )

ELL antibody WB image
ELL

 ELL ANTIBODY TARGET DESCRIPTION:
Synonym Names for ELL antibody: ELL; C19orf17, DKFZp434I1916, ELL1, ELL_HUMAN, Men; Eleven-nineteen lysine-rich leukemia protein; Elongation factor RNA polymerase II; RNA polymerase II elongation factor ELL

ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally. ELL resembles Elon

Function: Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.

Subunit: Interacts with EAF1 and EAF2.

Subcellular Location: Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with EAF2 to nuclear speckles. Also localized to Cajal (coiled) bodies.

Tissue Specificity: Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes.

Ptm: Phosphorylated upon DNA damage, probably by ATM or ATR.

Disease: A chromosomal translocation involving ELL is found in acute leukemias. Translocation t(11;19)(q23;p13.1) with MLL/HRX. The result is a rogue activator protein.

Similarity: Belongs to the ELL/occludin family.

ELL (elongation factor RNA polymerase II) reacts with human, dog.

OMIM: 600284; gene. [NCBI / EBI]

Products similar to ELL antibody:
 Cell_Lines
    Human Stabilin-2, Cos-7 Cells, Cell_Lines
    Human Stabilin-2, CHO Cells, Cell_Lines
    PCNA [PC10], IgG
    CDK5 [DC17], IgG
    IL2-R alpha [IL2R.1], IgG
 PRODUCT INTERACTIONS:
SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
 BACKGROUND REFERENCES for ELL ANTIBODY:
Background references for antibody target are not specific to GenWay products
Wiederschain.D.. (2003) Mol. Cell. Biol. 23 (12). 4230-4246.
Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.

Precautions: ELL antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.

Important Notes: During shipment, small volumes of ELL antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.

Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about ELL antibody, all related information, articles, resources about ELL antibody are being stored on our online database. Let us know if you have questions regarding this product.

Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed.

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