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| MAFB (v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)) Antibody, Rabbit Polyclonal Antibody |
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| Catalog Number: 18-003-43434 |
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| Trial Size Available. Please expect delivery of trial size products to be 4 weeks. |
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| Related Product Names:
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MAFB antibody; MAFB; KRML; MAFB (v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian))
- V-maf musculoaponeurotic fibrosarcoma oncogene homolog B; Transcription factor MAFB; Transcription factor MafB |
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- Gene Information -
Information in yellow represents specific gene information and does not necessarily represent specific product details. For more information please contact sales@genwaybio.com.
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| Gene Name: MAFB |
Gene Name Synonym: KRML |
Gi #:
23308699 |
NCBI Acc #:
NP_005452.2 |
Swiss Prot Acc #:
Q9Y5Q3 |
Length (aa): 323 |
Mol. Weight (Da): 35792 |
Chrom Location: N/A |
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 Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human MAFB.
Western Blot: Suggested dilution at 0.25 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
ELISA Titre: 1:62500
Category: Transcription Factor Antibodies
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Source/Host: Rabbit
Purity/Purification: Rabbit Ig G is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Crossreactivity: Human, Rat, Zebra Fish
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Shipping: Products may be shipped on ice pack or dry ice. |
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| APPLICATIONS for MAFB ANTIBODY: |
| IHC-P. WB: Tested |
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| MAFB ANTIBODY TARGET DESCRIPTION: |
Synonym Names for MAFB antibody: MAFB; KRML; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B; Transcription factor MAFB; Transcription factor MafB
MAFB is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns.
Function: Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells (By similarity).
Subunit: Interacts with the intracellular cytoplasmic domain of LRP1 (LRPICD). This interaction results in a moderate reduction of MAFB transcriptional potential.
Subcellular Location: Nucleus (By similarity).
Domain: The leucine-zipper domain is involved in the interaction with LRPICD.
Similarity: Belongs to the bZIP family. Maf subfamily.
Similarity: Contains 1 bZIP domain.
Summary: The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This protein contains no introns.
MAFB (v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)) reacts with human, rat, zebra fish.
OMIM: 608968; gene. [NCBI / EBI]
Products similar to MAFB antibody:
IgG
 MAFB (v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)), IgG
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SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. Find blocking buffers, stop reagents, chemiluminescent substrates, diluents, Immunohistochemistry reagents & more.
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| BACKGROUND
REFERENCES for MAFB ANTIBODY: |
| Background references for antibody target are not specific to GenWay products |
| Bakri.Y.. (2005) Blood 105 (7). 2707-2716. |
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Order Confirmation: Sales order confirmations are sent out upon the receipt of all orders. Please contact GenWay if you do not receive a confirmation within 1 business day of submitting your order.
Precautions: MAFB antibody is for in vitro research use only. Not for use in diagnostics or therapeutic procedures.
Important Notes: During shipment, small volumes of MAFB antibody vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. Actual concentration, volume and quantity will be printed on the vial's label. Please refer to the vials label for this information.
Copyright: This GenWay TDS is copyrighted. This datasheet is produced based partially on data from Swiss-Prot/TrEMBL and NCBI. To better serve our clients with everything we know about MAFB antibody, all related information, articles, resources about MAFB antibody are being stored on our online database. Let us know if you have questions regarding this product.
Disclaimer: For documents and software available from this server, GenWay neither warrants nor assumes any legal liability or responsibility for the accuracy, completeness or utility of any information, product or process disclosed. |
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Thank you for visiting GenWay Biotech's Datasheet. GenWay is the world's leader in chicken, IgY antibody production, producing over 900 quality polyclonal IgY antibodies to date. From our unique recombinant protein production, utilizing a variety of protein expression systems, GenWay's polyclonal IgY antibodies incorporate more epitopes, increasing the success rate for ELISA, western blot, immunohistochemistry (IHC), immunocytochemistry (ICC), and many more immunoassays. |
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